-
1
-
-
0023520170
-
A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and high-dose leucovorin versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma
-
Petrelli N, Herrera L, Rustum Y, Burke P, Creaven P, Stulc J, et al. A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and high-dose leucovorin versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma. J Clin Oncol 1987;5:1559-65.
-
(1987)
J Clin Oncol
, vol.5
, pp. 1559-1565
-
-
Petrelli, N.1
Herrera, L.2
Rustum, Y.3
Burke, P.4
Creaven, P.5
Stulc, J.6
-
2
-
-
0031019918
-
Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: a French intergroup study
-
de Gramont A, Bosset JF, Milan C, Rougier P, Bouché O, Etienne PL, et al. Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: a French intergroup study. J Clin Oncol 1997;15:808-15.
-
(1997)
J Clin Oncol
, vol.15
, pp. 808-815
-
-
de Gramont, A.1
Bosset, J.F.2
Milan, C.3
Rougier, P.4
Bouché, O.5
Etienne, P.L.6
-
3
-
-
0029813416
-
Weekly high-dose leucovorin versus low-dose leucovorin combined with fluorouracil in advanced colorectal cancer: results of a randomized multicenter trial. Study Group for Palliative Treatment of Metastatic Colorectal Cancer Study Protocol
-
Jäger E, Heike M, Bernhard H, Klein O, Bernhard G, Lautz D, et al. Weekly high-dose leucovorin versus low-dose leucovorin combined with fluorouracil in advanced colorectal cancer: results of a randomized multicenter trial. Study Group for Palliative Treatment of Metastatic Colorectal Cancer Study Protocol. J Clin Oncol 1996;14:2274-9.
-
(1996)
J Clin Oncol
, vol.14
, pp. 2274-2279
-
-
Jäger, E.1
Heike, M.2
Bernhard, H.3
Klein, O.4
Bernhard, G.5
Lautz, D.6
-
4
-
-
0027436244
-
The benefit of lucovorin-modulated fluorouracil as postoperative adjuvant therapy for primary colon cancer: results from National Surgical Adjuvant Breast and Bowel Project protocol C-03
-
Wolmark N, Rockette H, Fisher B, Wickerham DL, Redmond C, Fisher ER, et al. The benefit of lucovorin-modulated fluorouracil as postoperative adjuvant therapy for primary colon cancer: results from National Surgical Adjuvant Breast and Bowel Project protocol C-03. J Clin Oncol 1993;11:1879-87.
-
(1993)
J Clin Oncol
, vol.11
, pp. 1879-1887
-
-
Wolmark, N.1
Rockette, H.2
Fisher, B.3
Wickerham, D.L.4
Redmond, C.5
Fisher, E.R.6
-
5
-
-
33746805967
-
Randomized controlled trial of reduced-dose bolus fluorouracil plus leucovorin and irinotecan or infused fluorouracil plus leucovorin and oxaliplatin in patients with previously untreated metastatic colorectal cancer: a North American Intergroup Trial
-
Goldberg RM, Sargent DJ, Morton RF, Fuchs CS, Ramanathan RK, Williamson SK, et al. Randomized controlled trial of reduced-dose bolus fluorouracil plus leucovorin and irinotecan or infused fluorouracil plus leucovorin and oxaliplatin in patients with previously untreated metastatic colorectal cancer: a North American Intergroup Trial. J Clin Oncol 2006;24:3347-53.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3347-3353
-
-
Goldberg, R.M.1
Sargent, D.J.2
Morton, R.F.3
Fuchs, C.S.4
Ramanathan, R.K.5
Williamson, S.K.6
-
6
-
-
0033198085
-
Oxaliplatin added to the simplified bimonthly leucovorin and 5-fluorouracil regimen as second-line therapy for metastatic colorectal cancer (FOLFOX6). GERCOR
-
Maindrault-Goebel F, Louvet C, André T, Carola E, Lotz JP, Molitor JL, et al. Oxaliplatin added to the simplified bimonthly leucovorin and 5-fluorouracil regimen as second-line therapy for metastatic colorectal cancer (FOLFOX6). GERCOR. Eur J Cancer 1999;35:1338-42.
-
(1999)
Eur J Cancer
, vol.35
, pp. 1338-1342
-
-
Maindrault-Goebel, F.1
Louvet, C.2
André, T.3
Carola, E.4
Lotz, J.P.5
Molitor, J.L.6
-
7
-
-
1842569206
-
A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer
-
Goldberg RM, Sargent DJ, Morton RF, Fuchs CS, Ramanathan RK, Williamson SK, et al. A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 2004;22:23-30.
-
(2004)
J Clin Oncol
, vol.22
, pp. 23-30
-
-
Goldberg, R.M.1
Sargent, D.J.2
Morton, R.F.3
Fuchs, C.S.4
Ramanathan, R.K.5
Williamson, S.K.6
-
8
-
-
7644244310
-
Mortality associated with daily bolus 5-fluorouracil/leucovorin administered in combination with either irinotecan or oxaliplatin: results from Intergroup Trail N9741
-
Delaunoit T, Goldberg RM, Sargent DJ, Morton RF, Fuchs CS, Findlay BP, et al. Mortality associated with daily bolus 5-fluorouracil/leucovorin administered in combination with either irinotecan or oxaliplatin: results from Intergroup Trail N9741. Cancer 2004;101:2170-6.
-
(2004)
Cancer
, vol.101
, pp. 2170-2176
-
-
Delaunoit, T.1
Goldberg, R.M.2
Sargent, D.J.3
Morton, R.F.4
Fuchs, C.S.5
Findlay, B.P.6
-
9
-
-
0037068330
-
A 'modified de Gramont' regimen of fluorouracil, alone and with oxaliplatin, for advanced colorectal cancer
-
Cheeseman SL, Joel SP, Chester JD, Wilson G, Dent JT, Richards FJ, et al. A 'modified de Gramont' regimen of fluorouracil, alone and with oxaliplatin, for advanced colorectal cancer. Br J Cancer 2002;87:393-9.
-
(2002)
Br J Cancer
, vol.87
, pp. 393-399
-
-
Cheeseman, S.L.1
Joel, S.P.2
Chester, J.D.3
Wilson, G.4
Dent, J.T.5
Richards, F.J.6
-
10
-
-
0033874892
-
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
-
de Gramont A, Figer A, Seymour M, Homerin M, Hmissi A, Cassidy J, et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 2000;18:2938-47.
-
(2000)
J Clin Oncol
, vol.18
, pp. 2938-2947
-
-
de Gramont, A.1
Figer, A.2
Seymour, M.3
Homerin, M.4
Hmissi, A.5
Cassidy, J.6
-
11
-
-
42949149159
-
Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study
-
Saltz LB, Clarke S, Díaz-Rubio E, Scheithauer W, Figer A, Wong R, et al. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 2008;26:2013-9.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2013-2019
-
-
Saltz, L.B.1
Clarke, S.2
Díaz-Rubio, E.3
Scheithauer, W.4
Figer, A.5
Wong, R.6
-
12
-
-
1342290189
-
FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study
-
Tournigand C, André T, Achille E, Lledo G, Flesh M, Mery-Mignard D, et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol 2004;22:229-37.
-
(2004)
J Clin Oncol
, vol.22
, pp. 229-237
-
-
Tournigand, C.1
André, T.2
Achille, E.3
Lledo, G.4
Flesh, M.5
Mery-Mignard, D.6
-
13
-
-
24644457747
-
Phase III randmized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicentre study of the Gruppo Oncologico Dell'Italia Meridionale
-
Colucci G, Gebbia V, Paoletti G, Giuliani F, Caruso M, Gebbia N, et al. Phase III randmized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicentre study of the Gruppo Oncologico Dell'Italia Meridionale. J Clin Oncol 2005;23:4866-75.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4866-4875
-
-
Colucci, G.1
Gebbia, V.2
Paoletti, G.3
Giuliani, F.4
Caruso, M.5
Gebbia, N.6
-
14
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomized trial
-
Douillard JY, Cunningham D, Roth AD, Navarro M, James RD, Karasek P, et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomized trial. Lancet 2000;355:1041-7.
-
(2000)
Lancet
, vol.355
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
Navarro, M.4
James, R.D.5
Karasek, P.6
-
15
-
-
0033198035
-
CPT-11 (irinotecan) addition to bimonthly, high-dose leucovorin and bolus and continuous-infusion 5-fluorouracil (FOLFIRI) for pretreated metastatic colorectal cancer. GERCOR
-
André T, Louvet C, Maindrault-Goebel F, Couteau C, Mabro M, Lotz JP, et al. CPT-11 (irinotecan) addition to bimonthly, high-dose leucovorin and bolus and continuous-infusion 5-fluorouracil (FOLFIRI) for pretreated metastatic colorectal cancer. GERCOR. Eur J Cancer 1999;35:1343-7.
-
(1999)
Eur J Cancer
, vol.35
, pp. 1343-1347
-
-
André, T.1
Louvet, C.2
Maindrault-Goebel, F.3
Couteau, C.4
Mabro, M.5
Lotz, J.P.6
-
16
-
-
20644432867
-
Bevacizumab in combination with fluorouracil and leucovorin: an active regimen for first-line metastatic colorectal cancer
-
Hurwitz HI, Fehrenbacher L, Hainsworth JD, Heim W, Berlin J, Holmgren E, et al. Bevacizumab in combination with fluorouracil and leucovorin: an active regimen for first-line metastatic colorectal cancer. J Clin Oncol 2005;23:3502-8.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3502-3508
-
-
Hurwitz, H.I.1
Fehrenbacher, L.2
Hainsworth, J.D.3
Heim, W.4
Berlin, J.5
Holmgren, E.6
-
17
-
-
20544471876
-
Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival of patients with metastatic colorectal cancer
-
Kabbinavar FF, Hambleton J, Mass RD, Hurwitz HI, Bergsland E, Sarkar S. Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival of patients with metastatic colorectal cancer. J Clin Oncol 2005;23:3706-12.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3706-3712
-
-
Kabbinavar, F.F.1
Hambleton, J.2
Mass, R.D.3
Hurwitz, H.I.4
Bergsland, E.5
Sarkar, S.6
-
18
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J, Heim W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004;350:2335-42.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
-
19
-
-
77149166354
-
XELOX-1/NO16966, a randomized phase III trial of first-line XELOX compared with FOLFOX4 for patients with metastatic colorectal cancer (MCRC): updated survival and tolerability results
-
Abst
-
Cassidy J, Clarke S, Diaz-Rubio E, Scheithauer W, Figer A, Wong R, et al. XELOX-1/NO16966, a randomized phase III trial of first-line XELOX compared with FOLFOX4 for patients with metastatic colorectal cancer (MCRC): updated survival and tolerability results. American Society of Clinical Oncology Gastrointestional Symposium 2009; Abst: 382.
-
(2009)
American Society of Clinical Oncology Gastrointestional Symposium
, pp. 382
-
-
Cassidy, J.1
Clarke, S.2
Diaz-Rubio, E.3
Scheithauer, W.4
Figer, A.5
Wong, R.6
-
20
-
-
53049092394
-
Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/folinic acid plus oxaliplatin (FOLFOX-4) as second-line therapy in metastatic colorectal cancer: a randomized phase III noninferiority study
-
Rothenberg ML, Cox JV, Butts C, Navarro M, Bang YJ, Goel R, et al. Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/folinic acid plus oxaliplatin (FOLFOX-4) as second-line therapy in metastatic colorectal cancer: a randomized phase III noninferiority study. Ann Oncol 2008;19:1720-6.
-
(2008)
Ann Oncol
, vol.19
, pp. 1720-1726
-
-
Rothenberg, M.L.1
Cox, J.V.2
Butts, C.3
Navarro, M.4
Bang, Y.J.5
Goel, R.6
-
21
-
-
77950494294
-
Effect of bevacizumab in older patients with metastatic colorectal cancer: pooled analysis of four randomized studies
-
Cassidy J, Saltz LB, Giantonio BJ, Kabbinavar FF, Hurwitz HI, Rohr UP. Effect of bevacizumab in older patients with metastatic colorectal cancer: pooled analysis of four randomized studies. J Cancer Res Clin Oncol 2010;136:737-43.
-
(2010)
J Cancer Res Clin Oncol
, vol.136
, pp. 737-743
-
-
Cassidy, J.1
Saltz, L.B.2
Giantonio, B.J.3
Kabbinavar, F.F.4
Hurwitz, H.I.5
Rohr, U.P.6
-
22
-
-
49049105525
-
Safety and efficacy of oxaliplatin and fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer (mCRC): results of the TREE study
-
Hochster HS, Hart LL, Ramanathan RK, Childs BH, Hainsworth JD, Cohn AL, et al. Safety and efficacy of oxaliplatin and fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer (mCRC): results of the TREE study. J Clin Oncol 2008;26:3523-9.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3523-3529
-
-
Hochster, H.S.1
Hart, L.L.2
Ramanathan, R.K.3
Childs, B.H.4
Hainsworth, J.D.5
Cohn, A.L.6
-
23
-
-
57849117384
-
New response evaluation criteria in solid tumours: revised RECIST guideline
-
(version 1.1)
-
Eisenhauer EA, Therasse P, Bogaerts J, Schwartzd LH, Sargent D, Ford R, et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer 2009;45:228-47.
-
(2009)
Eur J Cancer
, vol.45
, pp. 228-247
-
-
Eisenhauer, E.A.1
Therasse, P.2
Bogaerts, J.3
Schwartzd, L.H.4
Sargent, D.5
Ford, R.6
-
24
-
-
78650781050
-
Final results of bevacizumab (BV) plus capecitabine plus oxaliplatin (XELOX) as first-line therapy in Japanese patients (pts) with metastatic colorectal cancer (MCRC)
-
Abst
-
Muro K, Doi T, Boku N, Kato K, Komatsu Y, Yamaguchi K, et al. Final results of bevacizumab (BV) plus capecitabine plus oxaliplatin (XELOX) as first-line therapy in Japanese patients (pts) with metastatic colorectal cancer (MCRC). American Society of Clinical Oncology Gastrointestional Symposium 2010; Abst: 466.
-
(2010)
American Society of Clinical Oncology Gastrointestional Symposium
, pp. 466
-
-
Muro, K.1
Doi, T.2
Boku, N.3
Kato, K.4
Komatsu, Y.5
Yamaguchi, K.6
-
26
-
-
33845382806
-
Nonparametric estimation form incomplete observations
-
Kaplan EL, Meier P. Nonparametric estimation form incomplete observations. J Am Stat Assoc 1958;53:457-81.
-
(1958)
J Am Stat Assoc
, vol.53
, pp. 457-481
-
-
Kaplan, E.L.1
Meier, P.2
|