메뉴 건너뛰기




Volumn 20, Issue 1, 2011, Pages 210-215

Structure of Mycobacterium tuberculosis thioredoxin in complex with quinol inhibitor PMX464

Author keywords

Inhibitor complex; Mycobacterium tuberculosis; Quinol; Thioredoxin

Indexed keywords

HOMODIMER; PMX 464; PROTEIN INHIBITOR; THIOREDOXIN; UNCLASSIFIED DRUG;

EID: 78650783356     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.533     Document Type: Article
Times cited : (11)

References (28)
  • 1
    • 0033581124 scopus 로고    scopus 로고
    • Consensus statement. Global burden of tuberculosis: Estimated incidence, prevalence, and mortality by country
    • WHO Global Surveillance and Monitoring Project
    • Dye C, Scheele S, Dolin P, Pathania V, Raviglione MC (1999) Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project. JAMA 282: 677-686.
    • (1999) JAMA , vol.282 , pp. 677-686
    • Dye, C.1    Scheele, S.2    Dolin, P.3    Pathania, V.4    Raviglione, M.C.5
  • 2
    • 0035936760 scopus 로고    scopus 로고
    • Microbial pathogenesis of Mycobacterium tuberculosis: Dawn of a discipline
    • Glickman MS, Jacobs WR, Jr (2001) Microbial pathogenesis of Mycobacterium tuberculosis: dawn of a discipline. Cell 104: 477-485.
    • (2001) Cell , vol.104 , pp. 477-485
    • Glickman, M.S.1    Jacobs Jr., W.R.2
  • 3
    • 0027963346 scopus 로고
    • Stimulation or inhibition of the respiratory burst in cultured macrophages in a mycobacterium model: Initial stimulation is followed by inhibition after phagocytosis
    • Gordon AH, Hart PD (1994) Stimulation or inhibition of the respiratory burst in cultured macrophages in a mycobacterium model: initial stimulation is followed by inhibition after phagocytosis. Infect Immun 62: 4650-4651.
    • (1994) Infect Immun , vol.62 , pp. 4650-4651
    • Gordon, A.H.1    Hart, P.D.2
  • 4
    • 0032060482 scopus 로고    scopus 로고
    • Alkyl hydroperoxide reductase subunit C (AhpC) protects bacterial and human cells against reactive nitrogen intermediates
    • Chen L, Xie QW, Nathan C (1998) Alkyl hydroperoxide reductase subunit C (AhpC) protects bacterial and human cells against reactive nitrogen intermediates. Mol Cell 1: 795-805.
    • (1998) Mol Cell , vol.1 , pp. 795-805
    • Chen, L.1    Xie, Q.W.2    Nathan, C.3
  • 5
    • 0028836762 scopus 로고
    • Molecular biology, virulence, and pathogenicity of mycobacteria
    • Shinnick TM, King CH, Quinn FD (1995) Molecular biology, virulence, and pathogenicity of mycobacteria. Am J Med Sci 309: 92-98.
    • (1995) Am J Med Sci , vol.309 , pp. 92-98
    • Shinnick, T.M.1    King, C.H.2    Quinn, F.D.3
  • 6
    • 0028930320 scopus 로고
    • Molecular mechanisms of isoniazid resistance in Mycobacterium tuberculosis and Mycobacterium bovis
    • Rouse DA, Morris SL (1995) Molecular mechanisms of isoniazid resistance in Mycobacterium tuberculosis and Mycobacterium bovis. Infect Immun 63: 1427-1433.
    • (1995) Infect Immun , vol.63 , pp. 1427-1433
    • Rouse, D.A.1    Morris, S.L.2
  • 7
    • 0001293738 scopus 로고
    • Sterilization of tubercle bacilli by isonicotinic acid hydrazide and the incidence of variants resistant to the drug in vitro
    • Middlebrook G (1952) Sterilization of tubercle bacilli by isonicotinic acid hydrazide and the incidence of variants resistant to the drug in vitro. Am Rev Tuberc 65: 765-767.
    • (1952) Am Rev Tuberc , vol.65 , pp. 765-767
    • Middlebrook, G.1
  • 8
    • 0035979346 scopus 로고    scopus 로고
    • Evidence for isoniazid-dependent free radical generation catalyzed by Mycobacterium tuberculosis KatG and the isoniazidresistant mutant KatG(S315T)
    • Wengenack NL, Rusnak F (2001) Evidence for isoniazid-dependent free radical generation catalyzed by Mycobacterium tuberculosis KatG and the isoniazidresistant mutant KatG(S315T). Biochemistry 40: 8990-8996.
    • (2001) Biochemistry , vol.40 , pp. 8990-8996
    • Wengenack, N.L.1    Rusnak, F.2
  • 9
    • 21844442599 scopus 로고    scopus 로고
    • Structure and mechanism of the alkyl hydroperoxidase AhpC, a key element of the Mycobacterium tuberculosis defense system against oxidative stress
    • Guimaraes BG, Souchon H, Honore N, Saint-Joanis B, Brosch R, Shepard W, Cole ST, Alzari PM (2005) Structure and mechanism of the alkyl hydroperoxidase AhpC, a key element of the Mycobacterium tuberculosis defense system against oxidative stress. J Biol Chem 280: 25735-25742.
    • (2005) J Biol Chem , vol.280 , pp. 25735-25742
    • Guimaraes, B.G.1    Souchon, H.2    Honore, N.3    Saint-Joanis, B.4    Brosch, R.5    Shepard, W.6    Cole, S.T.7    Alzari, P.M.8
  • 10
    • 55749110937 scopus 로고    scopus 로고
    • Functional studies of multiple thioredoxins from Mycobacterium tuberculosis
    • Akif M, Khare G, Tyagi AK, Mande SC, Sardesai AA (2008) Functional studies of multiple thioredoxins from Mycobacterium tuberculosis. J Bacteriol 190: 7087-7095.
    • (2008) J Bacteriol , vol.190 , pp. 7087-7095
    • Akif, M.1    Khare, G.2    Tyagi, A.K.3    Mande, S.C.4    Sardesai, A.A.5
  • 11
    • 0033102656 scopus 로고    scopus 로고
    • Reduction of peroxides and dinitrobenzenes by Mycobacterium tuberculosis thioredoxin and thioredoxin reductase
    • Zhang Z, Hillas PJ, Ortiz de Montellano PR (1999) Reduction of peroxides and dinitrobenzenes by Mycobacterium tuberculosis thioredoxin and thioredoxin reductase. Arch Biochem Biophys 363: 19-26.
    • (1999) Arch Biochem Biophys , vol.363 , pp. 19-26
    • Zhang, Z.1    Hillas, P.J.2    Ortiz De Montellano, P.R.3
  • 12
    • 1042278885 scopus 로고    scopus 로고
    • Multiple thioredoxin-mediated routes to detoxify hydroperoxides in Mycobacterium tuberculosis
    • Jaeger T, Budde H, Flohe L, Menge U, Singh M, Trujillo M, Radi R (2004) Multiple thioredoxin-mediated routes to detoxify hydroperoxides in Mycobacterium tuberculosis. Arch Biochem Biophys 423: 182-191.
    • (2004) Arch Biochem Biophys , vol.423 , pp. 182-191
    • Jaeger, T.1    Budde, H.2    Flohe, L.3    Menge, U.4    Singh, M.5    Trujillo, M.6    Radi, R.7
  • 14
    • 0025883245 scopus 로고
    • Structural and functional relations among thioredoxins of different species
    • Eklund H, Gleason FK, Holmgren A (1991) Structural and functional relations among thioredoxins of different species. Proteins 11: 13-28.
    • (1991) Proteins , vol.11 , pp. 13-28
    • Eklund, H.1    Gleason, F.K.2    Holmgren, A.3
  • 16
    • 0024393963 scopus 로고
    • Thioredoxin and glutaredoxin systems
    • Holmgren A (1989) Thioredoxin and glutaredoxin systems. J Biol Chem 264: 13963-13966.
    • (1989) J Biol Chem , vol.264 , pp. 13963-13966
    • Holmgren, A.1
  • 19
    • 34047204205 scopus 로고    scopus 로고
    • 3́-Phosphoadenosine-5́-phosphosulfate reductase in complex with thioredoxin: A structural snapshot in the catalytic cycle
    • Chartron J, Shiau C, Stout CD, Carroll KS (2007) 3́- Phosphoadenosine-5́-phosphosulfate reductase in complex with thioredoxin: a structural snapshot in the catalytic cycle. Biochemistry 46: 3942-3951.
    • (2007) Biochemistry , vol.46 , pp. 3942-3951
    • Chartron, J.1    Shiau, C.2    Stout, C.D.3    Carroll, K.S.4
  • 20
    • 0029644240 scopus 로고
    • Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B
    • Qin J, Clore GM, Kennedy WM, Huth JR, Gronenborn AM (1995) Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B. Structure 3: 289-297.
    • (1995) Structure , vol.3 , pp. 289-297
    • Qin, J.1    Clore, G.M.2    Kennedy, W.M.3    Huth, J.R.4    Gronenborn, A.M.5
  • 21
    • 0030585150 scopus 로고    scopus 로고
    • The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal
    • Qin J, Clore GM, Kennedy WP, Kuszewski J, Gronenborn AM (1996) The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal. Structure 4: 613-620.
    • (1996) Structure , vol.4 , pp. 613-620
    • Qin, J.1    Clore, G.M.2    Kennedy, W.P.3    Kuszewski, J.4    Gronenborn, A.M.5
  • 22
    • 0028922586 scopus 로고
    • LIGPLOT: A program to generate schematic diagrams of protein-ligand interactions
    • Wallace AC, Laskowski RA, Thornton JM (1995) LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions. Protein Eng 8: 127-134.
    • (1995) Protein Eng , vol.8 , pp. 127-134
    • Wallace, A.C.1    Laskowski, R.A.2    Thornton, J.M.3
  • 24
    • 0003997743 scopus 로고    scopus 로고
    • MRC Laboratory of Molecular Chemistry, Cambridge
    • Leslie AGW (1998) MOSFLM v.6.0., MRC Laboratory of Molecular Chemistry, Cambridge.
    • (1998) MOSFLM v.6.0
    • Leslie, A.G.W.1
  • 26


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.