Myocardial perfusion alterations observed months after radiotherapy are related to the cellular damage

NuklearMedizin

Volumn 49, Issue 6, 2010, Pages 209-215

  Dogan, I ^a   Sezen, O ^a   Sonmez, B ^a   Zengin, A Y ^a   Yenilmez, E ^a   Yulug, E ^a   Abidin, I ^a   Bahat, Z ^a  

^a KARADENIZ TECHNICAL UNIVERSITY   (Turkey)

Author keywords

99mTc sestamibi; Cardiac damage; Cardiac toxicity; Myocardial perfusion scintigraphy; Radiation induced heart disease; Radiotheraphy

Indexed keywords

CARDIOSPECT; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; PERTECHNETIC ACID TC 99M; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD VESSEL INJURY; CANCER RADIOTHERAPY; CAPILLARY ENDOTHELIUM; CELL DAMAGE; CELL DEGENERATION; CONTROLLED STUDY; DOSIMETRY; DRUG DISTRIBUTION; DRUG UPTAKE; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART MUSCLE INJURY; HISTOPATHOLOGY; INJURY SEVERITY; MALE; MYOCARDIAL PERFUSION IMAGING; NICK END LABELING; NONHUMAN; RADIATION DOSE DISTRIBUTION; RADIATION INDUCED HEART DISEASE; RADIATION INJURY; RADIOACTIVITY; RAT; ULTRASTRUCTURE;

ANIMALS; CAPILLARIES; ENDOMYOCARDIAL FIBROSIS; HEART DISEASES; HEART VENTRICLES; MALE; RATS; RATS, WISTAR; TECHNETIUM TC 99M SESTAMIBI;

EID: 78650771123     PISSN: 00295566     EISSN: None     Source Type: Journal    
DOI: 10.3413/nukmed-0315-10-05     Document Type: Article

References (34)

1. Adams MJ, Hardenbergh PH, Constine LS et al. Radiation-associated cardiovascular disease. Crit Rev Oncol Hematol 2003; 45: 55-75.
2. Berry GJ, Jorden M. Pathology of radiation and anthracycline cardiotoxicity. Pediatr Blood Cancer 2005; 44: 630-637.
3. Kirac S. Radyasyon ve Kalp. Anadolu Kardiyoloji Derg 2001; 1: 276-282.
4. Goethals I, De Winter O, De Bondt P et al. The clinical value of nuclear medicine in the assessment of irradiation-induced and anthracycline-associated cardiac damage. Ann Oncol 2002; 13: 1331-1339.
5. Goethals I, Dierckx R, De Meerleer G et al. The role of nuclear medicine in the prediction and detection of radiation-associated normal pulmonary and cardiac damage. J Nucl Med 2003; 44: 1531-1539. (Pubitemid 39663371)
6. Gyenes G, Fornander T, Carlens P et al. Detection of radiation-induced myocardial damage by technetium-99m sestamibi scintigraphy. Eur J Nucl Med 1997; 24: 286-292. (Pubitemid 27165857)
7. Hardenbergh PH, Munley MT, Bentel GC et al. Cardiac perfusion changes in patients treated for breast cancer with radiation therapy and doxorubicin: preliminary results. Int J Radiat Oncol Biol Phys 2001; 49: 1023-1028. (Pubitemid 32184608)
8. Seddon B, Cook A, Gothard L et al. Detection of defects in myocardial perfusion imaging in patients with early breast cancer treated with radiotherapy. Radiother Oncol 2002; 64: 53-63. (Pubitemid 35223154)
9. Pierga JY, Maunoury C, Valette H et al. Follow-up thallium-201 scintigraphy after mantle field radiotherapy for Hodgkin's disease. Int J Radiat Oncol Biol Phys 1993; 25: 871-876. (Pubitemid 23123392)
10. Prosnitz RG, Marks LB. Radiation-induced heart disease: vigilance is still required. J Clin Oncol 2005; 23: 7391-7394. (Pubitemid 46291797)
11. Girinsky T, Cordova A, Rey A et al. Thallium-201 scintigraphy is not predictive of late cardiac complications in patients with Hodgkin's disease treated with mediastinal radiation. Int J Radiat Oncol Biol Phys 2000; 48: 1503-1506.
12. Tokatli F, Uzal C, Doganay L et al. The potential cardioprotective effects of amifostine in irradiated rats. Int J Radiat Oncol Biol Phys 2004; 58: 1228-1234. (Pubitemid 38314808)
13. 99mTc-MIBI to evaluate amifostine protection against doxorubicin cardiotoxicity in rats. Ann Nucl Med 2005; 19: 197-200.
14. 125I-BMIPP and 18F-FDG uptake in a transgenic mouse model of stunned myocardium. Eur J Nucl Med Mol Imaging 2003; 30: 431-439.
15. Kruse JJ, Strootman EG, Wondergem J. Effects of amifostine on radiation-induced cardiac damage. Acta Oncol 2003; 42: 4-9. (Pubitemid 36307878)
16. Yulug E, Tekinbas C, Ulusoy H et al. The effects of oxidative stress on the liver and ileum in rats caused by one-lung ventilation. J Surg Res 2007; 139: 253-260. (Pubitemid 46551160)
17. Kato K, Yin H, Agata J et al. Adrenomedullin gene delivery attenuates myocardial infarction and apoptosis after ischemia and reperfusion. Am J Physiol Heart Circ Physiol 2003; 285: H1506-1514. (Pubitemid 37169504)
18. Khan MY. Radiation-induced cardiomyopathy. I. An electron microscopic study of cardiac muscle cells. Am J Pathol 1973; 73: 131-146.
19. Gao M, Shirato H, Miyasaka K et al. Induction of growth factors in rat cardiac tissue by X irradiation. Radiat Res 2000; 153: 540-547. (Pubitemid 30252602)
20. Blankenberg F, Narula J, Strauss HW. In vivo detection of apoptotic cell death: a necessary measurement for evaluating therapy for myocarditis, ischemia, and heart failure. J Nucl Cardiol 1999; 6: 531-539.
21. Yaoita H, Maruyama Y. Intervention for apoptosis in cardiomyopathy. Heart Fail Rev 2008; 13: 181-191.
22. Eichhorn EJ, Bristow MR. Medical therapy can improve the biological properties of the chronically failing heart. A new era in the treatment of heart failure. Circulation 1996; 94: 2285-2296
23. Hancock SL, Tucker MA, Hoppe RT. Factors affecting late mortality from heart disease after treatment of Hodgkin's disease. JAMA 1993; 270: 1949-1955. (Pubitemid 23312611)
24. Gyenes G, Fornander T, Carlens P et al. Morbidity of ischemic heart disease in early breast cancer 15-20 years after adjuvant radiotherapy. Int J Radiat Oncol Biol Phys 1994; 28: 1235-1241. (Pubitemid 24118062)
25. Schultz-Hector S, Trott KR. Radiation-induced cardiovascular diseases: is the epidemiologic evidence compatible with the radiobiologic data? Int J Radiat Oncol Biol Phys 2007; 67: 10-18.
26. Schultz-Hector S, Kallfass E, Sund M. Radiation sequelae in the large arteries. A review of clinical and experimental data. Strahlenther Onkol. 1995; 171: 427-436.
27. Lauk S, Trott KR. Endothelial cell proliferation in the rat heart following local heart irradiation. Int J Radiat Biol 1990; 57: 1017-1030. (Pubitemid 20169423)
28. Schultz-Hector S. Experimental studies on the pathogenesis of damage in the heart. Recent Results Cancer Res 1993; 130: 145-156.
29. Wondergem J, van der Laarse A, van Ravels FJ et al. In vitro assessment of cardiac performance after irradiation using an isolated working rat heart preparation. Int J Radiat Biol 1991; 59: 1053-1068.
30. Cowen D, Gonzague-Casabianca L, Brenot-Rossi I et al. Thallium-201 perfusion scintigraphy in the evaluation of late myocardial damage in left-side breast cancer treated with adjuvant radiotherapy. Int J Radiat Oncol Biol Phys 1998; 41: 809-815. (Pubitemid 28285958)
31. Lauk S, Kiszel Z, Buschmann J et al. Radiation-induced heart disease in rats. Int J Radiat Oncol Biol Phys 1985; 11: 801-808.
32. Schultz-Hector S, Sund M, Thames HD. Fractionation response and repair kinetics of radiation-induced heart failure in the rat. Radiother Oncol 1992; 23: 33-40.
33. Fajardo LF, Stewart JR. Experimental radiation-induced heart disease. Am J Pathol 1970; 59: 299-316.
34. Lauk S, Ruth S, Trott KR. The effects of dose-fractionation on radiation-induced heart disease in rats. Radiother Oncol 1987; 8: 363-367. (Pubitemid 17115582)