Pathogenicity of swine influenza viruses possessing an avian or swine-origin PB2 polymerase gene evaluated in mouse and pig models

Virology

Volumn 410, Issue 1, 2011, Pages 1-6

  Ma, Wenjun ^a,b,c   Lager, Kelly M ^b   Li, Xi ^a,e   Janke, Bruce H ^c   Mosier, Derek A ^a   Painter, Laura E ^c   Ulery, Eva S ^c   Ma, Jingqun ^a   Lekcharoensuk, Porntippa ^c,f   Webby, Richard J ^d   Richt, Jürgen A ^a,b  

^a KANSAS STATE UNIVERSITY   (United States)

^b NATIONAL ANIMAL DISEASE CENTER   (United States)

^c IOWA STATE UNIVERSITY   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^e Harbin Veterinary Research Institute   (China)

^f KASETSART UNIVERSITY   (Thailand)

Author keywords

Pathogenicity; PB2; Swine influenza virus

Indexed keywords

GLUTAMIC ACID; LYSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AVIAN INFLUENZA VIRUS; CODON; CONTROLLED STUDY; EMBRYO; GENE MUTATION; GENETIC REASSORTMENT; HUMAN; HUMAN CELL; INFLUENZA VIRUS A H1N1; MOUSE; NONHUMAN; PRIORITY JOURNAL; SWINE; SWINE INFLUENZA; SWINE INFLUENZA VIRUS; VIRUS GENE; VIRUS VIRULENCE;

ANIMALS; CELL LINE; DISEASE MODELS, ANIMAL; DOGS; GENE EXPRESSION REGULATION, VIRAL; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; LUNG; MICE; MICE, INBRED BALB C; MUTATION; ORTHOMYXOVIRIDAE INFECTIONS; REASSORTANT VIRUSES; RNA REPLICASE; SWINE; VIRAL PROTEINS; VIRULENCE; VIRUS REPLICATION;

AVES; MUS; ORTHOMYXOVIRIDAE; SIMIAN IMMUNODEFICIENCY VIRUS; SUIDAE; SWINE INFLUENZA VIRUS;

EID: 78650755241     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2010.10.027     Document Type: Article

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