Transmembrane pH-gradient liposomes to treat cardiovascular drug intoxication

ACS Nano

Volumn 4, Issue 12, 2010, Pages 7552-7558

  Bertrand, Nicolas ^a   Bouvet, Céline ^a   Moreau, Pierre ^a   Leroux, Jean Christophe ^a,b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b ETH ZURICH   (Switzerland)

Author keywords

detoxification; diltiazem; lipid resuscitation; nanomedicine; pharmacokinetics; scavenging nanocarriers

Indexed keywords

ACTIVE METABOLITES; DETOXIFYING AGENTS; DILTIAZEM; IN-SITU; IN-VITRO; IN-VIVO; IONIZABLE COMPOUNDS; LIPID EMULSIONS; LONG-CIRCULATING LIPOSOMES; NANOCARRIERS; NANOMEDICINES; PH GRADIENTS; PHARMACOKINETICS AND PHARMACODYNAMICS; PHARMACOLOGICAL EFFECTS; PLASMA CONCENTRATION; SCAVENGING PROPERTIES; TIME CURVES; TISSUE DISTRIBUTIONS; TRANSMEMBRANES; TRAPPING PROPERTIES; UPTAKE CAPACITY;

ANIMALS; BIOMOLECULES; BLOOD PRESSURE; DETOXIFICATION; LIPOSOMES; MEDICAL NANOTECHNOLOGY; METABOLISM; METABOLITES; PH; PHARMACOKINETICS; PHOSPHOLIPIDS; RATS; RESUSCITATION;

DRUG DOSAGE;

CALCIUM CHANNEL BLOCKING AGENT; DEACETYLDILTIAZEM; DILTIAZEM; DRUG DERIVATIVE; LIPOSOME; MACROGOL DERIVATIVE;

ANIMAL; ARTICLE; CELL MEMBRANE; CHEMICALLY INDUCED DISORDER; CHEMISTRY; HYPOTENSION; MALE; METABOLISM; PH; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; CALCIUM CHANNEL BLOCKERS; CELL MEMBRANE; CHEMISTRY, PHARMACEUTICAL; DILTIAZEM; HYDROGEN-ION CONCENTRATION; HYPOTENSION; LIPOSOMES; MALE; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 78650737398     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn101924a     Document Type: Article

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