Fragment Docking to Proteins with the Multi-copy Simultaneous Search Methodology

Fragment-based Approaches in Drug Discovery

Volumn 34, Issue , 2006, Pages 125-146

  Stultz, Collin M ^a,b   Karplus, Martin ^c  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b USA   (United States)

^c HARVARD UNIVERSITY   (United States)

Author keywords

Comparison with GRID; Computional approaches; Drug discovery; Fragment docking to proteins; Fragment library design; Ligand Design with MCSS; MCSS in Practice; Multi copy simultaneous search methodology (MCSS method); Protein Flexibility and MCSS

Indexed keywords

FACSIMILE; PEPTIDES;

COMPARISON WITH GRID; COMPUTIONAL APPROACHES; DRUG DISCOVERY; LIBRARY DESIGNS; LIGAND DESIGN; MCSS IN PRACTICE; MULTI COPIES; PROTEIN FLEXIBILITY;

LIGANDS;

EID: 78650734429     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/3527608761.ch7     Document Type: Chapter

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