Administration of 400 μg of misoprostol to augment routine active management of the third stage of labor

International Journal of Gynecology and Obstetrics

Volumn 112, Issue 2, 2011, Pages 98-102

  Hofmeyr, G Justus ^a,b,c   Fawole, Bukola ^d   Mugerwa, Kidza ^e   Godi, N Patrick ^f   Blignaut, Quentin ^g   Mangesi, Lindeka ^a,b,c   Singata, Mandisa ^a,b,c   Brady, Leanne ^a,b,c   Blum, Jennifer ^h  

^a ROYAL LONDON HOSPITAL   (United Kingdom)

^b UNIVERSITY OF FORT HARE   (South Africa)

^c UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^d UNIVERSITY OF IBADAN   (Nigeria)

^e MULAGO HOSPITAL   (Uganda)

^f Rob Ferreira Hospital Nelspruit   (South Africa)

^g Dora Nginza Hospital   (South Africa)

^h GYNUITY HEALTH PROJECTS   (United States)

Author keywords

Misoprostol; Postpartum hemorrhage; Uterotonics

Indexed keywords

ERGOMETRINE; MISOPROSTOL; OXYTOCIN; PLACEBO;

ADULT; ARTICLE; CLINICAL TRIAL; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG SAFETY; FEMALE; FEVER; HUMAN; LABOR INDUCTION; LABOR STAGE 3; MAJOR CLINICAL STUDY; MATERNAL MORTALITY; MULTICENTER STUDY; NIGERIA; POSTPARTUM HEMORRHAGE; PRIORITY JOURNAL; PROPHYLAXIS; RANDOMIZED CONTROLLED TRIAL; RISK BENEFIT ANALYSIS; SHIVERING; SOUTH AFRICA; TREATMENT OUTCOME; UGANDA; VAGINAL DELIVERY;

EID: 78650726484     PISSN: 00207292     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijgo.2010.08.019     Document Type: Article

References (21)

1. D.O. Selo-Ojeme Primary postpartum haemorrhage J Obstet Gynecol 22 5 2002 463 469
2. B. Kodio, L. de Bernis, M. Ba, C. Ronsmans, G. Pison, and J.F. Etard Levels and causes of maternal mortality in Senegal Trop Med Int Health 7 6 2002 499 505
3. Department of Health, Welsh Office, Scottish Home and Health Department, and Department of Health and Social Security Report of confidential enquiries into maternal deaths in the United Kingdom 1991-1993 1996 HMSO London
4. Begley C.M., Gyte G.M., Murphy D.J., Devane D., McDonald S.J., and W. McGuire Active versus expectant management for women in the third stage of labour Cochrane Database Syst Rev 7 2010 CD007412
5. Cotter A.M., Ness A., and Tolosa J.E. Prophylactic oxytocin for the third stage of labour Cochrane Database Syst Rev 4 2001 CD001808
6. Liabsuetrakul T., Choobun T., Peeyananjarassri K., and Islam Q.M. Prophylactic use of ergot alkaloids in the third stage of labour Cochrane Database Syst Rev 2 2007 CD005456
7. McDonald S.J., Abbott J.M., and Higgins S.P. Prophylactic ergometrine-oxytocin versus oxytocin for the third stage of labour Cochrane Database Syst Rev 1 2004 CD000201
8. P. Lumbiganon, J. Hofmeyr, A.M. Gulmezoglu, A. Pinol, and J. Villar Misoprostol dose-related shivering and pyrexia in the third stage of labour Br J Obstet Gynecol 106 4 1999 304 308
9. A.M. Gülmezoglu, J. Villar, N.N. Ngoc, G. Piaggio, G. Carroli, and L. Adetoro The WHO multicentre double-blind randomized controlled trial to evaluate the use of misoprostol in the management of the third stage of labour Lancet 358 9283 2001 689 695
10. H. Abdel-Aleem, J. Villar, A.M. Gulmezoglu, S.A. Mostafa, A.A. Youssef, and M. Shokry The pharmacokinetics of the prostaglandin E1 analogue misoprostol in plasma and colostrum after postpartum oral administration Eur J Obstet Gynecol Reprod Biol 108 1 2003 25 28
11. Y.S. Chong, S. Chua, H. El-Refaey, W.L. Choo, B. Chanrachakul, and B.C. Tai Postpartum intrauterine pressure studies of the uterotonic effect of oral misoprostol and intramuscular syntometrine Br J Obstet Gynecol 108 1 2001 41 47
12. G.J. Hofmeyr, G. Walraven, A.M. Gulmezoglu, B. Maholwana, Z. Alfirevic, and J. Villar Misoprostol to treat postpartum haemorrhage: a systematic review Br J Obstet Gynecol 112 5 2005 547 553
13. G.J. Hofmeyr, A.M. Gülmezoglu, N. Novikova, V. Linder, S. Ferreira, and G. Piaggio Misoprostol to prevent and treat postpartum haemorrhage: a systematic review and meta-analysis of maternal deaths and dose-related effects Bull World Health Organ 87 9 2009 666 677
14. M.L. McCormick, H.C. Sanghvi, B. Kinzie, and N. McIntosh Preventing postpartum haemorrhage in low-resource settings Int J Gynecol Obstet 77 3 2002 267 275
15. World Health Organisation WHO recommendations for the prevention of postpartum haemorrhage http://www.who.int/making-pregnancy-safer/publications/ WHORecommendationsforPPHaemorrhage.pdf Published 2007. Accessed 2010
16. C. Begg, M. Cho, S. Eastwood, R. Horton, D. Moher, and I. Olkin Improving the quality of reporting of randomized controlled trials. The CONSORT statement JAMA 276 8 1996 637 639
17. E. Calişkan, M.M. Meydanli, B. Dilbaz, B. Aykan, M. Sonmezer, and A. Haberal Is rectal misoprostol really effective in the treatment of third stage of labor? A randomized controlled trial Am J Obstet Gynecol 187 4 2002 1038 1045
18. E. Calişkan, B. Dilbaz, M.M. Meydanli, N. Ozturk, M.A. Narin, and A. Haberal Oral misoprostol for the third stage of labor: a randomized controlled trial Obstet Gynecol 101 5 Pt 1 2003 921 928
19. Fawole AO, Sotiloye OS, Hunyinbo KI, Umezulike AC, Okunlola MA, Adekanle DA, et al. Misoprostol and routine uterotonics for prevention of postpartum hemorrhage: A double-blind, randomized, placebo controlled trial. Int J Gynecol Obstet (in press).
20. B. Winikoff, R. Dabash, J. Durocher, E. Darwish, T.N. Nguyen, and W. León Treatment of post-partum haemorrhage with sublingual misoprostol versus oxytocin in women not exposed to oxytocin during labour: a double-blind, randomised, non-inferiority trial Lancet 375 9710 2010 210 216
21. J. Durocher, J. Blum, W. León, G. Barrera, and B. Winikoff High fever following postpartum administration of sublingual misoprostol Br J Obstet Gynecol 117 7 2010 845 852