메뉴 건너뛰기




Volumn 117, Issue 1, 2011, Pages 143-151

Clinical impact of amphiregulin expression in patients with epidermal growth factor receptor (EGFR) wild-type nonsmall cell lung cancer treated with EGFR-tyrosine kinase inhibitors

Author keywords

amphiregulin; epidermal growth factor receptor; nonsmall cell lung cancer; predictor; tyrosine kinase inhibitors; wild type

Indexed keywords

AMPHIREGULIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; GEFITINIB;

EID: 78650685308     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.25560     Document Type: Article
Times cited : (35)

References (30)
  • 1
    • 0037050352 scopus 로고    scopus 로고
    • Comparison of 4 chemotherapy regimens for advanced nonsmall-cell lung cancer
    • Schiller JH, Harrington D, Belani CP, et al. Comparison of 4 chemotherapy regimens for advanced nonsmall-cell lung cancer. N Engl J Med. 2002; 346: 92-98.
    • (2002) N Engl J Med. , vol.346 , pp. 92-98
    • Schiller, J.H.1    Harrington, D.2    Belani, C.P.3
  • 2
    • 45149084723 scopus 로고    scopus 로고
    • First-line gefitinib in patients with advanced nonsmall-cell lung cancer harboring somatic EGFR mutations
    • Sequist LV, Martins RG, Spigel D, et al. First-line gefitinib in patients with advanced nonsmall-cell lung cancer harboring somatic EGFR mutations. J Clin Oncol. 2008; 26: 2442-2449.
    • (2008) J Clin Oncol. , vol.26 , pp. 2442-2449
    • Sequist, L.V.1    Martins, R.G.2    Spigel, D.3
  • 3
    • 33947504732 scopus 로고    scopus 로고
    • Phase II clinical trial of chemotherapy-naive patients a≥70 years of age treated with erlotinib for advanced nonsmall-cell lung cancer
    • Jackman DM, Yeap BY, Lindeman NI, et al. Phase II clinical trial of chemotherapy-naive patients a≥70 years of age treated with erlotinib for advanced nonsmall-cell lung cancer. J Clin Oncol. 2007; 25: 760-766.
    • (2007) J Clin Oncol. , vol.25 , pp. 760-766
    • Jackman, D.M.1    Yeap, B.Y.2    Lindeman, N.I.3
  • 4
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated nonsmall-cell lung cancer
    • Shepherd FA, Rodrigues Pereira J, Ciuleanu T, et al. Erlotinib in previously treated nonsmall-cell lung cancer. N Engl J Med. 2005; 353: 123-132.
    • (2005) N Engl J Med. , vol.353 , pp. 123-132
    • Shepherd, F.A.1    Rodrigues Pereira, J.2    Ciuleanu, T.3
  • 5
    • 58149099349 scopus 로고    scopus 로고
    • Erlotinib for metastatic nonsmall-cell lung cancer: First-, second- or third-line setting - Does it matter? A single-institution experience
    • Ailawadhi S, Derby L, Natarajan R, Fetterly G, Reid M, Ramnath N., Erlotinib for metastatic nonsmall-cell lung cancer: first-, second- or third-line setting - does it matter? A single-institution experience. Oncology. 2009; 76: 85-90.
    • (2009) Oncology. , vol.76 , pp. 85-90
    • Ailawadhi, S.1    Derby, L.2    Natarajan, R.3    Fetterly, G.4    Reid, M.5    Ramnath, N.6
  • 6
    • 63049132774 scopus 로고    scopus 로고
    • First-line gefitinib for patients with advanced nonsmall-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy
    • Inoue A, Kobayashi K, Usui K, et al. First-line gefitinib for patients with advanced nonsmall-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy. J Clin Oncol. 2009; 27: 1394-1400.
    • (2009) J Clin Oncol. , vol.27 , pp. 1394-1400
    • Inoue, A.1    Kobayashi, K.2    Usui, K.3
  • 7
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science. 2004; 304: 1497-1500.
    • (2004) Science. , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3
  • 8
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of nonsmall-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of nonsmall-cell lung cancer to gefitinib. N Engl J Med. 2004; 350: 2129-2139.
    • (2004) N Engl J Med. , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 10
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M, et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A. 2004; 101: 13306-13311.
    • (2004) Proc Natl Acad Sci U S A. , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3
  • 11
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med. 2009; 361: 947-957.
    • (2009) N Engl J Med. , vol.361 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3
  • 12
    • 52449091935 scopus 로고    scopus 로고
    • Are there any ethnic differences in molecular predictors of erlotinib efficacy in advanced nonsmall cell lung cancer?
    • Ahn MJ, Park BB, Ahn JS, et al. Are there any ethnic differences in molecular predictors of erlotinib efficacy in advanced nonsmall cell lung cancer? Clin Cancer Res. 2008; 14: 3860-3866.
    • (2008) Clin Cancer Res. , vol.14 , pp. 3860-3866
    • Ahn, M.J.1    Park, B.B.2    Ahn, J.S.3
  • 13
    • 27244443759 scopus 로고    scopus 로고
    • Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: A Southwest Oncology Group study
    • Hirsch FR, Varella-Garcia M, McCoy J, et al. Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: a Southwest Oncology Group study. J Clin Oncol. 2005; 23: 6838-6845.
    • (2005) J Clin Oncol. , vol.23 , pp. 6838-6845
    • Hirsch, F.R.1    Varella-Garcia, M.2    McCoy, J.3
  • 14
    • 24644445676 scopus 로고    scopus 로고
    • Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive nonsmall-cell lung cancer patients
    • Cappuzzo F, Varella-Garcia M, Shigematsu H, et al. Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive nonsmall-cell lung cancer patients. J Clin Oncol. 2005; 23: 5007-5018.
    • (2005) J Clin Oncol. , vol.23 , pp. 5007-5018
    • Cappuzzo, F.1    Varella-Garcia, M.2    Shigematsu, H.3
  • 15
    • 14844366111 scopus 로고    scopus 로고
    • ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive nonsmall cell lung cancer cell lines
    • Engelman JA, Janne PA, Mermel C, et al. ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive nonsmall cell lung cancer cell lines. Proc Natl Acad Sci U S A. 2005; 102: 3788-3793.
    • (2005) Proc Natl Acad Sci U S A. , vol.102 , pp. 3788-3793
    • Engelman, J.A.1    Janne, P.A.2    Mermel, C.3
  • 16
    • 34548238762 scopus 로고    scopus 로고
    • Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab
    • Khambata-Ford S, Garrett CR, Meropol NJ, et al. Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab. J Clin Oncol. 2007; 25: 3230-3237.
    • (2007) J Clin Oncol. , vol.25 , pp. 3230-3237
    • Khambata-Ford, S.1    Garrett, C.R.2    Meropol, N.J.3
  • 17
    • 33745714256 scopus 로고    scopus 로고
    • Amphiregulin contributes to the transformed phenotype of human hepatocellular carcinoma cells
    • Castillo J, Erroba E, Perugorria MJ, et al. Amphiregulin contributes to the transformed phenotype of human hepatocellular carcinoma cells. Cancer Res. 2006; 66: 6129-6138.
    • (2006) Cancer Res. , vol.66 , pp. 6129-6138
    • Castillo, J.1    Erroba, E.2    Perugorria, M.J.3
  • 18
    • 58149265465 scopus 로고    scopus 로고
    • Autocrine production of amphiregulin predicts sensitivity to both gefitinib and cetuximab in EGFR wild-type cancers
    • Yonesaka K, Zejnullahu K, Lindeman N, et al. Autocrine production of amphiregulin predicts sensitivity to both gefitinib and cetuximab in EGFR wild-type cancers. Clin Cancer Res. 2008; 14: 6963-6973.
    • (2008) Clin Cancer Res. , vol.14 , pp. 6963-6973
    • Yonesaka, K.1    Zejnullahu, K.2    Lindeman, N.3
  • 19
    • 71649102943 scopus 로고    scopus 로고
    • The increasing role of amphiregulin in nonsmall cell lung cancer
    • Busser B, Coll JL, Hurbin A., The increasing role of amphiregulin in nonsmall cell lung cancer. Pathol Biol (Paris). 2009; 57: 511-512.
    • (2009) Pathol Biol (Paris). , vol.57 , pp. 511-512
    • Busser, B.1    Coll, J.L.2    Hurbin, A.3
  • 20
    • 27144483349 scopus 로고    scopus 로고
    • Increases of amphiregulin and transforming growth factor-alpha in serum as predictors of poor response to gefitinib among patients with advanced nonsmall cell lung cancers
    • Ishikawa N, Daigo Y, Takano A, et al. Increases of amphiregulin and transforming growth factor-alpha in serum as predictors of poor response to gefitinib among patients with advanced nonsmall cell lung cancers. Cancer Res. 2005; 65: 9176-9184.
    • (2005) Cancer Res. , vol.65 , pp. 9176-9184
    • Ishikawa, N.1    Daigo, Y.2    Takano, A.3
  • 21
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse P, Arbuck SG, Eisenhauer EA, et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst. 2000; 92: 205-216.
    • (2000) J Natl Cancer Inst. , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 22
    • 72449160988 scopus 로고    scopus 로고
    • A randominzed phase III study of gefitinib versus standard chemotherapy (gemcitabine plus cisplatin) as a first-line treatment for never-smokers with advanced or metastatic adenocarcinoma of the lung [abstract]
    • July 21-August 4,; San Francisco, California.
    • Lee JS, Park K, Kim SW, et al. A randominzed phase III study of gefitinib versus standard chemotherapy (gemcitabine plus cisplatin) as a first-line treatment for never-smokers with advanced or metastatic adenocarcinoma of the lung [abstract]. Paper presented at: 13th World Conference on Lung Cancer; July 21-August 4, 2009; San Francisco, California.
    • (2009) 13th World Conference on Lung Cancer
    • Lee, J.S.1    Park, K.2    Kim, S.W.3
  • 23
    • 66749121947 scopus 로고    scopus 로고
    • Determinants of response to epidermal growth factor receptor tyrosine kinase inhibition in squamous cell carcinoma of the head and neck
    • Rogers SJ, Box C, Chambers P, et al. Determinants of response to epidermal growth factor receptor tyrosine kinase inhibition in squamous cell carcinoma of the head and neck. J Pathol. 2009; 218: 122-130.
    • (2009) J Pathol. , vol.218 , pp. 122-130
    • Rogers, S.J.1    Box, C.2    Chambers, P.3
  • 24
    • 0031907022 scopus 로고    scopus 로고
    • Evaluation of epidermal growth factor-related growth factors and receptors and of neoangiogenesis in completely resected stage I-IIIA nonsmall-cell lung cancer: Amphiregulin and microvessel count are independent prognostic indicators of survival
    • Fontanini G, De Laurentiis M, Vignati S, et al. Evaluation of epidermal growth factor-related growth factors and receptors and of neoangiogenesis in completely resected stage I-IIIA nonsmall-cell lung cancer: amphiregulin and microvessel count are independent prognostic indicators of survival. Clin Cancer Res. 1998; 4: 241-249.
    • (1998) Clin Cancer Res. , vol.4 , pp. 241-249
    • Fontanini, G.1    De Laurentiis, M.2    Vignati, S.3
  • 25
    • 66249091930 scopus 로고    scopus 로고
    • The HER-2 receptor and breast cancer: Ten years of targeted anti-HER-2 therapy and personalized medicine
    • Ross JS, Slodkowska EA, Symmans WF, Pusztai L, Ravdin PM, Hortobagyi GN., The HER-2 receptor and breast cancer: ten years of targeted anti-HER-2 therapy and personalized medicine. Oncologist. 2009; 14: 320-368.
    • (2009) Oncologist. , vol.14 , pp. 320-368
    • Ross, J.S.1    Slodkowska, E.A.2    Symmans, W.F.3    Pusztai, L.4    Ravdin, P.M.5    Hortobagyi, G.N.6
  • 26
    • 19944427851 scopus 로고    scopus 로고
    • Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer
    • Amann J, Kalyankrishna S, Massion PP, et al. Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer. Cancer Res. 2005; 65: 226-235.
    • (2005) Cancer Res. , vol.65 , pp. 226-235
    • Amann, J.1    Kalyankrishna, S.2    Massion, P.P.3
  • 27
    • 73349098041 scopus 로고    scopus 로고
    • Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab
    • Jacobs B, De Roock W, Piessevaux H, et al. Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab. J Clin Oncol. 2009; 27: 5068-5074.
    • (2009) J Clin Oncol. , vol.27 , pp. 5068-5074
    • Jacobs, B.1    De Roock, W.2    Piessevaux, H.3
  • 28
    • 39749085844 scopus 로고    scopus 로고
    • TACE/ADAM-17: A component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer
    • Merchant NB, Voskresensky I, Rogers CM, et al. TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer. Clin Cancer Res. 2008; 14: 1182-1191.
    • (2008) Clin Cancer Res. , vol.14 , pp. 1182-1191
    • Merchant, N.B.1    Voskresensky, I.2    Rogers, C.M.3
  • 29
    • 55449123441 scopus 로고    scopus 로고
    • Clinical significance of pretreatment serum amphiregulin and transforming growth factor-alpha, and an epidermal growth factor receptor somatic mutation in patients with advanced nonsquamous, nonsmall cell lung cancer
    • Masago K, Fujita S, Hatachi Y, et al. Clinical significance of pretreatment serum amphiregulin and transforming growth factor-alpha, and an epidermal growth factor receptor somatic mutation in patients with advanced nonsquamous, nonsmall cell lung cancer. Cancer Sci. 2008; 99: 2295-2301.
    • (2008) Cancer Sci. , vol.99 , pp. 2295-2301
    • Masago, K.1    Fujita, S.2    Hatachi, Y.3
  • 30
    • 77649270674 scopus 로고    scopus 로고
    • Amphiregulin promotes BAX inhibition and resistance to gefitinib in nonsmall-cell lung cancers
    • Busser B, Sancey L, Josserand V, et al. Amphiregulin promotes BAX inhibition and resistance to gefitinib in nonsmall-cell lung cancers. Mol Ther. 2010; 18: 528-535.
    • (2010) Mol Ther. , vol.18 , pp. 528-535
    • Busser, B.1    Sancey, L.2    Josserand, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.