Jerdonuxin, a novel snaclec (snake C-type lectin) with platelet aggregation activity from Trimeresurus jerdonii venom

Toxicon

Volumn 57, Issue 1, 2011, Pages 109-116

  Chen, Zhong Ming ^a,b   Wu, Jian Bo ^a   Zhang, Yong ^a   Yu, Guo Yu ^a   Lee, Wen Hui ^a   Lu, Qiu Min ^a   Zhang, Yun ^a  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Glycoprotein Ib; Jerdonuxin; Molecular cloning; Platelet aggregation; Purification

Indexed keywords

COMPLEMENTARY DNA; JERDONUXIN; LECTIN; SNAKE VENOM; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SEQUENCE; HUMAN; HUMAN CELL; MOLECULAR CLONING; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ISOLATION; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; SEQUENCE ANALYSIS; THROMBOCYTE AGGREGATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; COAGULANTS; CROTALID VENOMS; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ANTAGONISM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; LECTINS, C-TYPE; MOLECULAR SEQUENCE DATA; PLATELET AGGREGATION; SEQUENCE ALIGNMENT; TRIMERESURUS;

TRIMERESURUS JERDONII;

EID: 78650679581     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2010.10.011     Document Type: Article

References (27)

1. Andrews R.K., Berndt M.C. Snake venom modulators of platelet adhesion receptors and their ligands. Toxicon 2000, 38:775-791.
2. Chan J.C., Kwok M.M., Cockram C.S., Prematilleke M.N., Tomlinson B., Critchley J.A. Blood coagulation abnormalities associated with envenoming by Trimeresurus albolabris in Hong Kong. Singapore Med. J. 1993, 34:145-147.
3. Chen R.Q., Jin Y., Wu J.B., Zhou X.D., Li D.S., Lu Q.M., Wang W.Y., Xiong Y.L. A novel high molecular weight metalloproteinase cleaves fragment F1 of activated human prothrombin. Toxicon 2004, 44:281-287.
4. Chen R.Q., Jin Y., Wu J.B., Zhou X.D., Lu Q.M., Wang W.Y., Xiong Y.L. A new protein structure of P-II class snake venom metalloproteinases: it comprises metalloproteinase and disintegrin domains. Biochem. Biophys. Res. Commun. 2003, 310:182-187.
5. Chung C.H., Au L.C., Huang T.F. Molecular cloning and sequence analysis of aggretin, a collagen-like platelet aggregation inducer. Biochem. Biophys. Res. Commun. 1999, 263:723-727.
6. Clemetson J.M., Polgar J., Magnenat E., Wells T.N., Clemetson K.J. The platelet collagen receptor glycoprotein VI is a member of the immunoglobulin superfamily closely related to FcalphaR and the natural killer receptors. J. Biol. Chem. 1999, 274:29019-29024.
7. Clemetson K.J., Lu Q., Clemetson J.M. Snake C-type lectin-like proteins and platelet receptors. Pathophysiol. Haemost. Thromb. 2005, 34:150-155.
8. Clemetson K.J., Morita T., Manjunatha Kini R. Scientific and standardization committee communications: classification and nomenclature of snake venom C-type lectins and related proteins. J. Thromb. Haemost. 2009, 7:360.
9. Clemetson K.J., Navdaev A., Dormann D., Du X.Y., Clemetson J.M. Multifunctional snake C-type lectins affecting platelets. Haemostasis 2001, 31:148-154.
10. Clemetson K.J., Polgar J., Clemetson J.M. Snake venom C-type lectins as tools in platelet research. Platelets 1998, 9:165-169.
11. Fukuda K., Mizuno H., Atoda H., Morita T. Crystal structure of flavocetin-A, a platelet glycoprotein Ib-binding protein, reveals a novel cyclic tetramer of C-type lectin-like heterodimers. Biochemistry 2000, 39:1915-1923.
12. Huang K.F., Ko T.P., Hung C.C., Chu J., Wang A.H., Chiou S.H. Crystal structure of a platelet-agglutinating factor isolated from the venom of Taiwan habu (Trimeresurus mucrosquamatus). Biochem. J. 2004, 378:399-407.
13. Jasti J., Paramasivam M., Srinivasan A., Singh T.P. Crystal structure of echicetin from Echis carinatus (Indian saw-scaled viper) at 2.4 A resolution. J. Mol. Biol. 2004, 335:167-176.
14. Kawasaki T., Fujimura Y., Usami Y., Suzuki M., Miura S., Sakurai Y., Makita K., Taniuchi Y., Hirano K., Titani K. Complete amino acid sequence and identification of the platelet glycoprotein Ib-binding site of jararaca GPIb-BP, a snake venom protein isolated from Bothrops jararaca. J. Biol. Chem. 1996, 271:10635-10639.
15. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685.
16. Lee W.H., Du X.Y., Lu Q.M., Clemetson K.J., Zhang Y. Stejnulxin, a novel snake C-type lectin-like protein from Trimeresurus stejnegeri venom is a potent platelet agonist acting specifically via GPVI. Thromb. Haemost. 2003, 90:662-671.
17. Lu Q., Navdaev A., Clemetson J.M., Clemetson K.J. GPIb is involved in platelet aggregation induced by mucetin, a snake C-type lectin protein from Chinese habu (Trimeresurus mucrosquamatus) venom. Thromb. Haemost. 2004, 91:1168-1176.
18. Lu Q.M., Jin Y., Li D.S., Wang W.Y., Xiong Y.L. Characterization of a thrombin-like enzyme from the venom of Trimeresurus jerdonii. Toxicon 2000, 38:1225-1236.
19. Morrissey J.H. Silver stain for proteins in polyacrylamide gels: a modified procedure with enhanced uniform sensitivity. Anal. Biochem. 1981, 117:307-310.
20. Peng M., Holt J.C., Niewiarowski S. Isolation, characterization and amino acid sequence of echicetin beta subunit, a specific inhibitor of von Willebrand factor and thrombin interaction with glycoprotein Ib. Biochem. Biophys. Res. Commun. 1994, 205:68-72.
21. Polgar J., Magnenat E.M., Peitsch M.C., Wells T.N., Saqi M.S., Clemetson K.J. Amino acid sequence of the alpha subunit and computer modelling of the alpha and beta subunits of echicetin from the venom of Echis carinatus (saw-scaled viper). Biochem. J. 1997, 323(Pt 2):533-537.
22. Shin Y., Okuyama I., Hasegawa J., Morita T. Molecular cloning of glycoprotein Ib-binding protein, flavocetin-A, which inhibits platelet aggregation. Thromb. Res. 2000, 99:239-247.
23. Suzuki-Inoue K., Fuller G.L., Garcia A., Eble J.A., Pohlmann S., Inoue O., Gartner T.K., Hughan S.C., Pearce A.C., Laing G.D., Theakston R.D., Schweighoffer E., Zitzmann N., Morita T., Tybulewicz V.L., Ozaki Y., Watson S.P. A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2. Blood 2006, 107:542-549.
24. Taniuchi Y., Kawasaki T., Fujimura Y. The high molecular mass, glycoprotein Ib-binding protein flavocetin-A induces only small platelet aggregates in vitro. Thromb. Res. 2000, 97:69-75.
25. Wei Q., Lu Q.M., Jin Y., Li R., Wei J.F., Wang W.Y., Xiong Y.L. Purification and cloning of a novel C-type lectin-like protein with platelet aggregation activity from Trimeresurus mucrosquamatus venom. Toxicon 2002, 40:1331-1338.
26. Zha H.G., Lee W.H., Zhang Y. Cloning of cDNAs encoding C-type lectins from Elapidae snakes Bungarus fasciatus and Bungarus multicinctus. Toxicon 2001, 39:1887-1892.
27. Zhou X.D., Jin Y., Chen R.Q., Lu Q.M., Wu J.B., Wang W.Y., Xiong Y.L. Purification, cloning and biological characterization of a novel disintegrin from Trimeresurus jerdonii venom. Toxicon 2004, 43:69-75.