A naturally occurring, soluble antagonist of human IL-23 inhibits the development and in vitro function of human Th17 cells

Journal of Immunology

Volumn 185, Issue 12, 2010, Pages 7302-7308

  Yu, Raymond Y ^a   Gallagher, Grant ^a  

^a HUMIGEN LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 21; INTERLEUKIN 23 RECEPTOR ANTAGONIST; INTERLEUKIN 4; INTERLEUKIN 6; MESSENGER RNA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG INHIBITION; DRUG RECEPTOR BINDING; ENTERITIS; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; IN VITRO STUDY; INFLAMMATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TH17 CELL;

CELL DIFFERENTIATION; CELL LINE; CYTOKINES; EXONS; HUMANS; INTERLEUKIN-23; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, INTERLEUKIN; RNA, MESSENGER; STAT3 TRANSCRIPTION FACTOR; TH17 CELLS;

EID: 78650675876     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1002410     Document Type: Article

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