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Volumn 53, Issue 13, 2010, Pages 787-792
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Syntheses of the tricyclic cores of clozapine, dibenzo[b,f][1,4]thiazepin- 11(10H)-one, and dibenzo[b,f][1,4]oxazepin-11(10H)-one in C-14 labeled form by [14C]carbonylation
a
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Author keywords
amoxapine; clozapine; loxapine; tricyclic ring
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Indexed keywords
METABOLISM;
PROTEINS;
AMOXAPINE;
CARBONYLATIONS;
CLOZAPINE;
COVALENT BINDING;
COVALENT MODIFICATIONS;
DRUG METABOLISMS;
LOXAPINE;
METABOLIC ACTIVATION;
SIDE EFFECT;
TRICYCLIC RING;
CARBONYLATION;
2 MERCAPTO BENZOIC ACID C 14;
8 CHLORO 5H DIBENZO[B,E][1,4]DIAZEPIN 11 (10H)ONE C 14;
CLOZAPINE;
CLOZAPINE C 14;
DIBENZOTHIAZEPINE C 14;
DIBENZOXAPINE C 14;
DIBENZO[B,F][1,4]OXAZEPIN 11 (10H)ONE C 14;
DIBENZO[B,F][14]THIAZEPIN 11 (10H)ONE C 14;
DRUG METABOLITE;
METHYL 2 (2 AMINOPHENYLTHIO)BENZOATE C 14;
METHYL 2 (2 NITROPHENYLTHIO)BENZOATE C 14;
UNCLASSIFIED DRUG;
ARTICLE;
BINDING ASSAY;
CARBON NUCLEAR MAGNETIC RESONANCE;
CARBONYLATION;
CARBOXYLATION;
CONTROLLED STUDY;
COVALENT BOND;
DRUG METABOLISM;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
ISOTOPE LABELING;
PROTON NUCLEAR MAGNETIC RESONANCE;
RADIOCHEMISTRY;
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EID: 78650658514
PISSN: 03624803
EISSN: 10991344
Source Type: Journal
DOI: 10.1002/jlcr.1802 Document Type: Article |
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Times cited : (15)
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References (12)
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