-
1
-
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0242713784
-
The synthesis of radioactive cholesterol and fatty acids in vitro
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Brady, R. O., and Gurin, S. (1951) The synthesis of radioactive cholesterol and fatty acids in vitro. J. Biol. Chem. 189, 371-377
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(1951)
J. Biol. Chem.
, vol.189
, pp. 371-377
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-
Brady, R.O.1
Gurin, S.2
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2
-
-
0012829747
-
The biosynthesis of radioactive fatty acids and cholesterol
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Brady, R. O., and Gurin, S. (1950) The biosynthesis of radioactive fatty acids and cholesterol. J. Biol. Chem. 186, 461-469
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(1950)
J. Biol. Chem.
, vol.186
, pp. 461-469
-
-
Brady, R.O.1
Gurin, S.2
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3
-
-
0000544075
-
The biosynthesis of labeled fatty acids and cholesterol in experimental diabetes
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Brady, R. O., and Gurin, S. (1950) The biosynthesis of labeled fatty acids and cholesterol in experimental diabetes. J. Biol. Chem. 187, 589-596
-
(1950)
J. Biol. Chem.
, vol.187
, pp. 589-596
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-
Brady, R.O.1
Gurin, S.2
-
4
-
-
78650672707
-
Synthesis of radioactive fatty acids in vitro and its hormonal control
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Brady, R. O., Lukens, F. D. W., and Gurin, S. (1951) Synthesis of radioactive fatty acids in vitro and its hormonal control. J. Biol. Chem. 193, 459-464
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(1951)
J. Biol. Chem.
, vol.193
, pp. 459-464
-
-
Brady, R.O.1
Lukens, F.D.W.2
Gurin, S.3
-
5
-
-
58149443711
-
The biosynthesis of radioactive long chain fatty acids by homogenized pigeon liver tissue
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Brady, R. O., and Gurin, S. (1951) The biosynthesis of radioactive long chain fatty acids by homogenized pigeon liver tissue. Arch. Biochem. Biophys. 34, 221-222
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(1951)
Arch. Biochem. Biophys.
, vol.34
, pp. 221-222
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-
Brady, R.O.1
Gurin, S.2
-
6
-
-
0000239848
-
The biosynthesis of fatty acids by cell-free or water-soluble enzyme systems
-
Brady, R. O., and Gurin, S. (1952) The biosynthesis of fatty acids by cell-free or water-soluble enzyme systems. J. Biol. Chem. 199, 421-431
-
(1952)
J. Biol. Chem.
, vol.199
, pp. 421-431
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-
Brady, R.O.1
Gurin, S.2
-
7
-
-
77049157594
-
The biosynthesis of fatty acids in cell-free systems
-
Brady, R. O., and Gurin, S. (1952) The biosynthesis of fatty acids in cell-free systems. Brookhaven Symp. Biol. 5, 162-175
-
(1952)
Brookhaven Symp. Biol.
, vol.5
, pp. 162-175
-
-
Brady, R.O.1
Gurin, S.2
-
8
-
-
78650658807
-
Elaboration of steroid hormones by surviving adrenal tissue slices obtained from thermally stressed dogs
-
Brady, R. O., Walser, J., and Agranoff, B. W. (1953) Elaboration of steroid hormones by surviving adrenal tissue slices obtained from thermally stressed dogs. Proc. Soc. Exp. Biol. Med. 84, 634-636
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(1953)
Proc. Soc. Exp. Biol. Med.
, vol.84
, pp. 634-636
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-
Brady, R.O.1
Walser, J.2
Agranoff, B.W.3
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10
-
-
0041193557
-
Enzymatic thioltransacetylation
-
Brady, R. O., and Stadtman, E. R. (1954) Enzymatic thioltransacetylation. J. Biol. Chem. 211, 621-629
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(1954)
J. Biol. Chem.
, vol.211
, pp. 621-629
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-
Brady, R.O.1
Stadtman, E.R.2
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11
-
-
34547129927
-
The enzymatic synthesis of fatty acids by aldol condensation
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Brady, R. O. (1958) The enzymatic synthesis of fatty acids by aldol condensation. Proc. Natl. Acad. Sci. U.S.A. 44, 993-998
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(1958)
Proc. Natl. Acad. Sci. U.S.A.
, vol.44
, pp. 993-998
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-
Brady, R.O.1
-
12
-
-
78650652192
-
Biosynthesis of fatty acids. II. Studies with enzymes obtained from brain
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Brady, R. O. (1960) Biosynthesis of fatty acids. II. Studies with enzymes obtained from brain. J. Biol. Chem. 235, 3099-3103
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(1960)
J. Biol. Chem.
, vol.235
, pp. 3099-3103
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-
Brady, R.O.1
-
14
-
-
0006154876
-
Biosynthesis of sphingosine in vitro
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Brady, R. O., and Koval, G. J. (1957) Biosynthesis of sphingosine in vitro. J. Am. Chem. Soc. 79, 2648-2649
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(1957)
J. Am. Chem. Soc.
, vol.79
, pp. 2648-2649
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-
Brady, R.O.1
Koval, G.J.2
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15
-
-
0007458527
-
The incorporation of galactose into galactolipids
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Buton, R. M., Sodd, M. A., and Brady, R. O. (1958) The incorporation of galactose into galactolipids. J. Biol. Chem. 233, 1053-1060
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(1958)
J. Biol. Chem.
, vol.233
, pp. 1053-1060
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-
Buton, R.M.1
Sodd, M.A.2
Brady, R.O.3
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16
-
-
84918777562
-
Cerebrosidespeicherung bei Splenomegalie Typus Gaucher
-
Lieb, H. (1924) Cerebrosidespeicherung bei Splenomegalie Typus Gaucher. Ztschr. Physiol. Chem. 140, 305-313
-
(1924)
Ztschr. Physiol. Chem.
, vol.140
, pp. 305-313
-
-
Lieb, H.1
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19
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0038465685
-
Cerebroside synthesis in Gaucher's disease
-
Trams, E. G., and Brady, R. O. (1960) Cerebroside synthesis in Gaucher's disease. J. Clin. Invest. 39, 1546-1550
-
(1960)
J. Clin. Invest.
, vol.39
, pp. 1546-1550
-
-
Trams, E.G.1
Brady, R.O.2
-
20
-
-
0000717064
-
Studies on sphingolipids. VII. Synthesis and configuration of natural sphingomyelins
-
Shapiro, D., and Flowers, H. M. (1962) Studies on sphingolipids. VII. Synthesis and configuration of natural sphingomyelins. J. Am. Chem. Soc. 84, 1047-1050
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(1962)
J. Am. Chem. Soc.
, vol.84
, pp. 1047-1050
-
-
Shapiro, D.1
Flowers, H.M.2
-
21
-
-
0038465682
-
The metabolism of glucocerebrosides. I. Purification and properties of a glucocerebroside-cleaving enzyme from spleen tissue
-
Brady, R. O., Kanfer, J., and Shapiro, D. (1965) The metabolism of glucocerebrosides. I. Purification and properties of a glucocerebroside-cleaving enzyme from spleen tissue. J. Biol. Chem. 240, 39-42
-
(1965)
J. Biol. Chem.
, vol.240
, pp. 39-42
-
-
Brady, R.O.1
Kanfer, J.2
Shapiro, D.3
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22
-
-
50549198437
-
Metabolism of glucocerebrosides. II. Evidence of an enzymatic deficiency in Gaucher's disease
-
Brady, R. O., Kanfer, J. N., and Shapiro, D. (1965) Metabolism of glucocerebrosides. II. Evidence of an enzymatic deficiency in Gaucher's disease. Biochem. Biophys. Res. Commun. 18, 221-225
-
(1965)
Biochem. Biophys. Res. Commun.
, vol.18
, pp. 221-225
-
-
Brady, R.O.1
Kanfer, J.N.2
Shapiro, D.3
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23
-
-
0013927537
-
Demonstration of a deficiency of glucocerebroside-cleaving enzyme in Gaucher's disease
-
Brady, R. O., Kanfer, J. N., Bradley, R. M., and Shapiro, D. (1966) Demonstration of a deficiency of glucocerebroside-cleaving enzyme in Gaucher's disease. J. Clin. Invest. 45, 1112-1115
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(1966)
J. Clin. Invest.
, vol.45
, pp. 1112-1115
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-
Brady, R.O.1
Kanfer, J.N.2
Bradley, R.M.3
Shapiro, D.4
-
24
-
-
0014428383
-
The lysosomal localization of sphingolipid hydrolases
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Weinreb, N. J., Brady, R. O., and Tappel, A. L. (1968) The lysosomal localization of sphingolipid hydrolases. Biochim. Biophys. Acta 159, 141-146
-
(1968)
Biochim. Biophys. Acta
, vol.159
, pp. 141-146
-
-
Weinreb, N.J.1
Brady, R.O.2
Tappel, A.L.3
-
25
-
-
78650670483
-
The chemical innovators: Unearthing a biochemical rosetta stone
-
Feb. 22
-
Brady, R. O. (Feb. 22, 1971) The Chemical Innovators: unearthing a biochemical Rosetta Stone. Chemical & Engineering News
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(1971)
Chemical & Engineering News
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-
Brady, R.O.1
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26
-
-
0013881132
-
The metabolism of sphingomyelin. II. Evidence of an enzymatic deficiency in Niemann- Pick disease
-
Brady, R. O., Kanfer, J. N., Mock, M. B., and Fredrickson, D. S. (1966) The metabolism of sphingomyelin. II. Evidence of an enzymatic deficiency in Niemann- Pick disease. Proc. Natl. Acad. Sci. U.S.A. 55, 366-369
-
(1966)
Proc. Natl. Acad. Sci. U.S.A.
, vol.55
, pp. 366-369
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-
Brady, R.O.1
Kanfer, J.N.2
Mock, M.B.3
Fredrickson, D.S.4
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27
-
-
0014216741
-
Enzymatic defect in Fabry's disease: Ceramidetrihexosidase deficiency
-
Brady, R. O., Gal, A. E., Bradley, R. M., Martensson, E., Warshaw, A. L., and Laster, L. (1967) Enzymatic defect in Fabry's disease: Ceramidetrihexosidase deficiency. N. Engl. J. Med. 276, 1163-1167
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(1967)
N. Engl. J. Med.
, vol.276
, pp. 1163-1167
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-
Brady, R.O.1
Gal, A.E.2
Bradley, R.M.3
Martensson, E.4
Warshaw, A.L.5
Laster, L.6
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28
-
-
0014687950
-
Demonstration of an alteration of ganglioside metabolism in Tay-Sachs disease
-
Kolodny, E. H., Brady, R. O., and Volk, B. W. (1969) Demonstration of an alteration of ganglioside metabolism in Tay-Sachs disease. Biochem. Biophys. Res. Commun. 37, 526-531
-
(1969)
Biochem. Biophys. Res. Commun.
, vol.37
, pp. 526-531
-
-
Kolodny, E.H.1
Brady, R.O.2
Volk, B.W.3
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29
-
-
0015391437
-
The metabolism of Tay-Sachs ganglioside: Catabolic studies with lysosomal enzymes from normal and Tay-Sachs brain tissue
-
Tallman, J. F., Johnson, W. G., and Brady, R. O. (1972) The metabolism of Tay-Sachs ganglioside: catabolic studies with lysosomal enzymes from normal and Tay-Sachs brain tissue. J. Clin. Invest. 51, 2339-2345
-
(1972)
J. Clin. Invest.
, vol.51
, pp. 2339-2345
-
-
Tallman, J.F.1
Johnson, W.G.2
Brady, R.O.3
-
30
-
-
0014193935
-
The diagnosis of Gaucher's disease and Niemann-Pick disease using small samples of venous blood
-
Kampine, J. P., Brady, R. O., Kanfer, J. N., Feld, M., and Shapiro, D. (1967) The diagnosis of Gaucher's disease and Niemann-Pick disease using small samples of venous blood. Science 155, 86-88
-
(1967)
Science
, vol.155
, pp. 86-88
-
-
Kampine, J.P.1
Brady, R.O.2
Kanfer, J.N.3
Feld, M.4
Shapiro, D.5
-
31
-
-
0015252395
-
Adult Gaucher's disease: Kindred studies and demonstration of a deficiency of acid β-glucosidase in cultured fibroblasts
-
Ho, M. W., Seck, J., Schmidt, D., Veath, M. L., Johnson, W. G., Brady, R. O., and O'Brien, J. S. (1972) Adult Gaucher's disease: kindred studies and demonstration of a deficiency of acid β-glucosidase in cultured fibroblasts. Am. J. Hum. Genet. 24, 37-45
-
(1972)
Am. J. Hum. Genet.
, vol.24
, pp. 37-45
-
-
Ho, M.W.1
Seck, J.2
Schmidt, D.3
Veath, M.L.4
Johnson, W.G.5
Brady, R.O.6
O'brien, J.S.7
-
32
-
-
0015133018
-
Identification of heterozygous carriers of lipid storage diseases
-
Brady, R. O., Johnson, W. G., and Uhlendorf, B. W. (1971) Identification of heterozygous carriers of lipid storage diseases. Am. J. Med. 51, 423-431
-
(1971)
Am. J. Med.
, vol.51
, pp. 423-431
-
-
Brady, R.O.1
Johnson, W.G.2
Uhlendorf, B.W.3
-
33
-
-
0015216216
-
Fabry's disease: Antenatal detection
-
Brady, R. O., Uhlendorf, B. W., and Jacobson, C. B. (1971) Fabry's disease: antenatal detection. Science 172, 174-175
-
(1971)
Science
, vol.172
, pp. 174-175
-
-
Brady, R.O.1
Uhlendorf, B.W.2
Jacobson, C.B.3
-
34
-
-
0015123431
-
In utero diagnosis of Niemann-Pick disease
-
Epstein, C. J., Brady, R. O., Schneider, E. L., Bradley, R. M., and Shapiro, D. (1971) In utero diagnosis of Niemann-Pick disease. Am. J. Hum. Genet. 23, 533-535
-
(1971)
Am. J. Hum. Genet.
, vol.23
, pp. 533-535
-
-
Epstein, C.J.1
Brady, R.O.2
Schneider, E.L.3
Bradley, R.M.4
Shapiro, D.5
-
35
-
-
0015458249
-
Infantile (type II) Gaucher's disease: In utero diagnosis and fetal pathology
-
Schneider, E. L., Ellis, W. G., Brady, R. O., McCulloch, J. R., and Epstein, C. J. (1972) Infantile (type II) Gaucher's disease: in utero diagnosis and fetal pathology. J. Pediatr. 81, 1134-1139
-
(1972)
J. Pediatr.
, vol.81
, pp. 1134-1139
-
-
Schneider, E.L.1
Ellis, W.G.2
Brady, R.O.3
McCulloch, J.R.4
Epstein, C.J.5
-
36
-
-
0014012410
-
Sphingolipidoses
-
Brady, R. O. (1966) Sphingolipidoses. N. Engl. J. Med. 275, 312-318
-
(1966)
N. Engl. J. Med.
, vol.275
, pp. 312-318
-
-
Brady, R.O.1
-
37
-
-
0006423440
-
Ceramidetrihexosidase from human placenta
-
Johnson, W. G., and Brady, R. O. (1972) Ceramidetrihexosidase from human placenta. Methods Enzymol. XXVIII, 849-856
-
(1972)
Methods Enzymol.
, vol.28
, pp. 849-856
-
-
Johnson, W.G.1
Brady, R.O.2
-
38
-
-
0015915183
-
Replacement therapy for inherited enzyme deficiency: Use of purified ceramidetrihexosidase in Fabry's disease
-
Brady, R. O., Tallman, J. F., Johnson, W. G., Gal, A. E., Leahy, W. E., Quirk, J. M., and Dekaban, A. S. (1973) Replacement therapy for inherited enzyme deficiency: use of purified ceramidetrihexosidase in Fabry's disease. N. Engl. J. Med. 289, 9-14
-
(1973)
N. Engl. J. Med.
, vol.289
, pp. 9-14
-
-
Brady, R.O.1
Tallman, J.F.2
Johnson, W.G.3
Gal, A.E.4
Leahy, W.E.5
Quirk, J.M.6
Dekaban, A.S.7
-
39
-
-
0015805171
-
Isolation and characterization of glucocerebrosidase from human placental tissue
-
Pentchev, P. G., Brady, R. O., Hibbert, S. R., Gal, A. E., and Shapiro, D. (1973) Isolation and characterization of glucocerebrosidase from human placental tissue. J. Biol. Chem. 248, 5256-5261
-
(1973)
J. Biol. Chem.
, vol.248
, pp. 5256-5261
-
-
Pentchev, P.G.1
Brady, R.O.2
Hibbert, S.R.3
Gal, A.E.4
Shapiro, D.5
-
40
-
-
0016201884
-
Replacement therapy for inherited enzyme deficiency: Use of purified glucocerebrosidase in Gaucher's disease
-
Brady, R. O., Pentchev, P. G., Gal, A. E., Hibbert, S. R., and Dekaban, A. S. (1974) Replacement therapy for inherited enzyme deficiency: use of purified glucocerebrosidase in Gaucher's disease. N. Engl. J. Med. 291, 989-993
-
(1974)
N. Engl. J. Med.
, vol.291
, pp. 989-993
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-
Brady, R.O.1
Pentchev, P.G.2
Gal, A.E.3
Hibbert, S.R.4
Dekaban, A.S.5
-
41
-
-
0016731001
-
Replacement therapy for inherited enzyme deficiency: Sustained clearance of accumulated glucocerebroside in Gaucher's disease following infusion of purified glucocerebrosidase
-
Pentchev, P. G., Brady, R. O., Gal, A. E., and Hibbert, S. R. (1975) Replacement therapy for inherited enzyme deficiency: sustained clearance of accumulated glucocerebroside in Gaucher's disease following infusion of purified glucocerebrosidase. J. Mol. Med. 1, 73-78
-
(1975)
J. Mol. Med.
, vol.1
, pp. 73-78
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-
Pentchev, P.G.1
Brady, R.O.2
Gal, A.E.3
Hibbert, S.R.4
-
42
-
-
0017708011
-
Enzyme replacement therapy in Gaucher's disease: Large-scale purification of glucocerebrosidase suitable for human administration
-
Furbish, F. S., Blair, H. E., Shiloach, J., Pentchev, P. G., and Brady, R. O. (1977) Enzyme replacement therapy in Gaucher's disease: large-scale purification of glucocerebrosidase suitable for human administration. Proc. Natl. Acad. Sci. U.S.A. 74, 3560-3563
-
(1977)
Proc. Natl. Acad. Sci. U.S.A.
, vol.74
, pp. 3560-3563
-
-
Furbish, F.S.1
Blair, H.E.2
Shiloach, J.3
Pentchev, P.G.4
Brady, R.O.5
-
43
-
-
0007862318
-
Enzyme replacement therapy: Specific targeting of exogenous enzymes to storage cells
-
(Martonosi, A. N., ed), Plenum Publishing Corp., New York
-
Brady, R. O., and Furbish, F. S. (1982) Enzyme replacement therapy: specific targeting of exogenous enzymes to storage cells. In: Membranes and Transport (Martonosi, A. N., ed) Vol. 2, pp. 587-592, Plenum Publishing Corp., New York
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(1982)
Membranes and Transport
, vol.2
, pp. 587-592
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Brady, R.O.1
Furbish, F.S.2
-
44
-
-
0025236339
-
Therapeutic response to intravenous infusions of glucocerebrosidase in a patient with Gaucher's disease
-
Barton, N. W., Furbish, F. S., Murray, G. J., Garfield, M., and Brady, R. O. (1990) Therapeutic response to intravenous infusions of glucocerebrosidase in a patient with Gaucher's disease. Proc. Natl. Acad. Sci. U.S.A. 87, 1913-1916
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 1913-1916
-
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Barton, N.W.1
Furbish, F.S.2
Murray, G.J.3
Garfield, M.4
Brady, R.O.5
-
45
-
-
0025869216
-
Replacement therapy for inherited enzyme deficiency: Macrophage-targeted glucocerebrosidase for Gaucher's disease
-
Barton, N. W., Brady, R. O., Dambrosia, J. M., DiBisceglie, A. M., Doppelt, S. H., Hill, S. C., Mankin, H. J., Murray, G. J., Parker, R. I., Argoff, C. E., Grewal, R. P., and Yu, K.-T. (1991) Replacement therapy for inherited enzyme deficiency: macrophage-targeted glucocerebrosidase for Gaucher's disease. N. Engl. J. Med. 324, 1464-1470
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(1991)
N. Engl. J. Med.
, vol.324
, pp. 1464-1470
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-
Barton, N.W.1
Brady, R.O.2
Dambrosia, J.M.3
Dibisceglie, A.M.4
Doppelt, S.H.5
Hill, S.C.6
Mankin, H.J.7
Murray, G.J.8
Parker, R.I.9
Argoff, C.E.10
Grewal, R.P.11
Yu, K.-T.12
-
46
-
-
0028883136
-
Enzyme therapy in Gaucher's disease type 1: Comparative efficacy of mannoseterminated glucocerebrosidase from natural and recombinant sources
-
Grabowski, G. A., Barton, N. W., Pastores, G., Dambrosia, J. M., Banerjee, T. K., McKee, M. A., Parker, C., Schiffmann, R., Hill, S. C., and Brady, R. O. (1995) Enzyme therapy in Gaucher's disease type 1: comparative efficacy of mannoseterminated glucocerebrosidase from natural and recombinant sources. Ann. Int. Med. 122, 33-39
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(1995)
Ann. Int. Med.
, vol.122
, pp. 33-39
-
-
Grabowski, G.A.1
Barton, N.W.2
Pastores, G.3
Dambrosia, J.M.4
Banerjee, T.K.5
McKee, M.A.6
Parker, C.7
Schiffmann, R.8
Hill, S.C.9
Brady, R.O.10
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