Adolescent with treatment-refractory schizophrenia and clozapine-induced cardiomyopathy managed with high-dose olanzapine

Journal of Child and Adolescent Psychopharmacology

Volumn 20, Issue 6, 2010, Pages 539-543

  Bobb, Vanessa Toney ^a,b   Jarskog, L Fredrik ^c,d   Coffey, Barbara J ^e,f  

^a Queens Children's Psychiatric Center   (United States)

^b NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^e NEW YORK UNIVERSITY   (United States)

^f NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMANTADINE; ARIPIPRAZOLE; BENZATROPINE; CLONAZEPAM; CLOZAPINE; HALOPERIDOL; LORAZEPAM; OLANZAPINE; PROPRANOLOL; RISPERIDONE; ZIPRASIDONE;

ADOLESCENT; AKATHISIA; CARDIOMYOPATHY; CASE REPORT; CATATONIA; CLINICAL FEATURE; CONFERENCE PAPER; DISEASE COURSE; DRUG DOSE REDUCTION; DRUG EFFECT; DRUG MEGADOSE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; HUMAN; HYPERSALIVATION; MALE; PSYCHOSIS; SCHIZOPHRENIA; SEDATION; SIDE EFFECT; TREATMENT RESPONSE;

ADOLESCENT; ANTIPSYCHOTIC AGENTS; BENZODIAZEPINES; CARDIOMYOPATHIES; CLOZAPINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MALE; SCHIZOPHRENIA; TREATMENT OUTCOME;

EID: 78650652604     PISSN: 10445463     EISSN: None     Source Type: Journal    
DOI: 10.1089/cap.2010.2062     Document Type: Conference Paper

References (14)

1. Azorin JM, Spiegel R, Remington G, Vanelle JM, Péré JJ, Giguere M, Bourdeix I: A double-blind comparative study of clozapine and risperidone in the management of severe chronic schizophrenia. Am J Psychiatry 158:1305-1313, 2001.
2. Cooper LT: Myocarditis. N Engl J Med 360:1526-1538, 2009.
3. Correll CU, Manu P, Olshanskiy V, Napolitano B, Kane JM, Malhotra AK: Cardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents. JAMA 302:1765-1773, 2009.
4. Coulter DM, Bate A, Meyboom RH, Lindquist M, Edwards IR: An-tipsychotic drugs and heart muscle disorder in international phar-macovigilance: Data mining study. BMJ 322:1207-1209, 2001.
5. Floreani J, Bastiampillai T: Successful re-challenge with clozapine following development of clozapine-induced cardiomyopathy. Aust N Z J Psychiatry 42:747-748, 2007.
6. Fontana PG, Sümegi B: Association of Clozaril (clozapine) with cardiovascular toxicity [Dear Healthcare Professional letter]. Quebec, Novartis Pharmaceuticals Canada Inc, 2002.
7. Kumra S, Oberstar JV, Sikich L, Findling RL, McClellan JM, Vinogradov S, Charles Schulz S: Efficacy and tolerability of second-generation antipsychotics in children and adolescents with schizophrenia. Schizophr Bull 34:60-71, 2008c.
8. Layland JJ, Liew D, Prior DL: Clozapine-induced cardiotoxicity: A clinical update. Med J Aust 190:190-192, 2009.
9. Meltzer HY, Bobo WV, Roy A, Jayathilake K, Chen Y, Ertugrul A, Anil Yǎ gciǒglu AE, Small JG: A randomized, double-blind comparison of clozapine and high-dose olanzapine in treatment-resistant patients with schizophrenia. J Clin Psychiatry 69:274-285, 2008.
10. Merrill DB, Ahmari SE, Bradford JM, Lieberman JA: Myocarditis during clozapine treatment. Am J Psychiatry.163:204-208, 2006.
11. Rostagno C, Di Norscia G, Placidi GF, Gensini GF: Beta-blocker and angiotensin-converting enzyme inhibitor may limit certain cardiac adverse effects of clozapine. Gen Hosp Psychiatry 30:280-283, 2008.
12. Shaw P, Sporn A, Gogtay N, Overman GP, Greenstein D, Gochman P, Tossell JW, Lenane M, Rapoport JL: Childhood-onset schizo-phrenica: A double-blind, randomized clozapine-olanzapine comparison. Arch Gen Psychiatry 63:721-730, 2006.
13. Tang WK, Ungvari GS: Efficacy of electroconvulsive therapy in treatment-resistant schizophrenia: A prospective open trial. Prog Neuropsychopharmacol Biol Psychiatry 27:373-379, 2003.
14. Volavka J, Czobor P, Sheitman B, Lindenmayer JP, Citrome L, McEvoy JP, Cooper TB, Chakos M, Lieberman JA: Clozapine, olanzapine, risperidone, and haloperidol in the treatment of patients with chronic schizophrenia and schizoaffective disorder. Am J Psychiatry 159:255-262, 2002. (Pubitemid 34126903)