Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates

Antimicrobial Agents and Chemotherapy

Volumn 55, Issue 1, 2011, Pages 373-375

  Feßler, Andrea T ^a   Kadlec, Kristina ^a   Schwarz, Stefan ^a  

^a FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; APRAMYCIN; CHLORAMPHENICOL; DALFOPRISTIN;

AMPA GENE; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; COW; GENE DELETION; GENE SEQUENCE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SWINE;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CATTLE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; NEBRAMYCIN; POLYMERASE CHAIN REACTION; SWINE;

EID: 78650648957     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01124-10     Document Type: Article

References (32)

1. Boerlin, P., R. Travis, C. L. Gyles, R. Reid-Smith, N. Janecko, H. Lim, V. Nicholson, S. A. McEwen, R. Friendship, and M. Archambault. 2005. Antimicrobial resistance and virulence genes of Escherichia coli isolates from swine in Ontario. Appl. Environ. Microbiol. 71:6753-6761.
2. Chaslus-Dancla, E., J. L. Martel, C. Carlier, J. P. Lafont, and P. Courvalin. 1986. Emergence of aminoglycoside 3-N-acetyltransferase IV in Escherichia coli and Salmonella typhimurium isolated from animals in France. Antimicrob. Agents Chemother. 29:239-243.
3. Chaslus-Dancla, E., P. Pohl, M. Meurisse, M. Marin, and J. P. Lafont. 1991. High genetic homology between plasmids of human and animal origins conferring resistance to the aminoglycosides gentamicin and apramycin. Antimicrob. Agents Chemother. 35:590-593.
4. CLSI. 2008. Performance standards for antimicrobial disk and dilution susceptibility test for bacteria isolated from animals; approved standard-third edition. CLSI document M31-A3. Clinical and Laboratory Standards Institute, Wayne, PA.
5. Davies, J., and S. O'Connor. 1978. Enzymatic modification of aminoglycoside antibiotics: 3-N-acetyltransferase with broad specificity that determines resistance to the novel aminoglycoside apramycin. Antimicrob. Agents Chemother. 14:69-72.
6. de Neeling, A. J., M. J. van den Broek, E. C. Spalburg, M. G. van Santen-Verheuvel, W. D. Dam-Deisz, H. C. Boshuizen, A. W. van de Giessen, E. van Duijkeren, and X. W. Huijsdens. 2007. High prevalence of methicillin resistant Staphylococcus aureus in pigs. Vet. Microbiol. 122:366-372.
7. Denis, O., C. Suetens, M. Hallin, B. Catry, I. Ramboer, M. Dispas, G. Willems, B. Gordts, P. Butaye, and M. J. Struelens. 2009. Methicillin-resistant Staphylococcus aureus ST398 in swine farm personnel, Belgium. Emerg. Infect. Dis. 15:1098-1101.
8. Feßler, A., C. Scott, K. Kadlec, R. Ehricht, S. Monecke, and S. Schwarz. 2010. Characterization of methicillin-resistant Staphylococcus aureus ST398 from cases of bovine mastitis. J. Antimicrob. Chemother. 65:619-625.
9. Kadlec, K., R. Ehricht, S. Monecke, U. Steinacker, H. Kaspar, J. Mankertz, and S. Schwarz. 2009. Diversity of antimicrobial resistance pheno-and genotypes of methicillin-resistant Staphylococcus aureus ST398 from diseased swine. J. Antimicrob. Chemother. 64:1156-1164.
10. Kadlec, K., and S. Schwarz. 2009. Identification of a novel trimethoprim resistance gene, dfrK, in a methicillin-resistant Staphylococcus aureus ST398 strain and its physical linkage to the tetracycline resistance gene tet(L). Antimicrob. Agents Chemother. 53:776-778.
11. Kadlec, K., and S. Schwarz. 2009. Identification of a novel ABC transporter gene, vga(C), located on a multiresistance plasmid from a porcine methicillin-resistant Staphylococcus aureus ST398 strain. Antimicrob. Agents Chemother. 53:3589-3591.
12. Kadlec, K., and S. Schwarz. 2010. Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. Antimicrob. Agents Chemother. 54:915-918.
13. Kehrenberg, C., C. Cuny, B. Strommenger, S. Schwarz, and W. Witte. 2009. Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfr. Antimicrob. Agents Chemother. 53:779-781.
14. Lüthje, P., and S. Schwarz. 2006. Antimicrobial resistance of coagulasenegative staphylococci from bovine subclinical mastitis with particular reference to macrolide-lincosamide resistance phenotypes and genotypes. J. Antimicrob. Chemother. 57:966-969.
15. Nemati, M., K. Hermans, U. Lipinska, O. Denis, A. Deplano, M. Struelens, L. A. Devriese, F. Pasmans, and F. Haesebrouck. 2008. Antimicrobial resistance of old and recent Staphylococcus aureus isolates from poultry: first detection of livestock-associated methicillin-resistant strain ST398. Antimicrob. Agents Chemother. 52:3817-3819.
16. Nienhoff, U., K. Kadlec, I. F. Chaberny, J. Verspohl, G.-F. Gerlach, S. Schwarz, D. Simon, and I. Nolte. 2009. Transmission of methicillin-resistant Staphylococcus aureus strains between humans and dogs: two case reports. J. Antimicrob. Chemother. 64:660-662.
17. Pomba, C., F. Baptista, N. Couto, F. Loução, and H. Hasman. 2010. Methicillin-resistant Staphylococcus aureus CC398 isolates with indistinguishable ApaI restriction patterns in colonized and infected pigs and humans. J. Antimicrob. Chemother. 65:2479-2481.
18. Schwarz, S., K. Kadlec, and B. Strommenger. 2008. Methicillin-resistant Staphylococcus aureus and Staphylococcus pseudintermedius detected in the BfT-GermVet monitoring programme 2004-2006 in Germany. J. Antimicrob. Chemother. 61:282-285.
19. Schwarz, S., C. Kehrenberg, B. Doublet, and A. Cloeckaert. 2004. Molecular basis of bacterial resistance to chloramphenicol and florfenicol. FEMS Microbiol. Rev. 28:519-542.
20. Smith, T. C., M. J. Male, A. L. Harper, J. S. Kroeger, G. P. Tinkler, E. D. Moritz, A. W. Capuano, L. A. Herwaldt, and D. J. Diekema. 2009. Methicillin-resistant Staphylococcus aureus (MRSA) strain ST398 is present in Midwestern U.S. swine and swine workers. PLoS One 4:e4258.
21. Threlfall, E. J., B. Rowe, J. L. Ferguson, and L. R. Ward. 1986. Characterization of plasmids conferring resistance to gentamicin and apramycin in strains of Salmonella typhimurium phage type 204c isolated in Britain. J. Hyg. (Lond.) 97:419-426.
22. van de Giessen, A. W., M. G. van Santen-Verheuvel, P. D. Hengeveld, T. Bosch, E. M. Broens, and C. B. Reusken. 2009. Occurrence of methicillinresistant Staphylococcus aureus in rats living on pig farms. Prev. Vet. Med. 91:270-273.
23. Vanderhaeghen, W., T. Cerpentier, C. Adriaensen, J. Vicca, K. Hermans, and P. Butaye. 2010. Methicillin-resistant Staphylococcus aureus (MRSA) ST398 associated with clinical and subclinical mastitis in Belgian cows. Vet. Microbiol. 144:166-171.
24. van Duijkeren, E., M. D. Jansen, S. C. Flemming, H. de Neeling, J. A. Wagenaar, A. H. W. Schoormans, A. van Nes, and A. C. Fluit. 2007. Methicillin-resistant Staphylococcus aureus in pigs with exudative epidermitis. Emerg. Infect. Dis. 13:1408-1410.
25. van Duijkeren, E., M. Moleman, M. M. Sloet van Oldruitenborgh-Oosterbaan, J. Multem, A. Troelstra, A. C. Fluit, W. J. van Wamel, D. J. Houwers, A. J. de Neeling, and J. A. Wagenaar. 2010. Methicillin-resistant Staphylococcus aureus in horses and horse personnel: an investigation of several outbreaks. Vet. Microbiol. 141:96-102.
26. Voss, A., F. Loeffen, J. Bakker, C. Klaassen, and M. Wulf. 2005. Methicillinresistant Staphylococcus aureus in pig farming. Emerg. Infect. Dis. 11:1965-1966.
27. Walther, B., S. Monecke, C. Ruscher, A. W. Friedrich, R. Ehricht, P. Slickers, A. Soba, C. G. Wleklinski, L. H. Wieler, and A. Lübke-Becker. 2009. Comparative molecular analysis substantiates zoonotic potential of equine methicillin-resistant Staphylococcus aureus. J. Clin. Microbiol. 47:704-710.
28. Witte, W., B. Strommenger, C. Stanek, and C. Cuny. 2007. Methicillinresistant Staphylococcus aureus ST398 in humans and animals, Central Europe. Emerg. Infect. Dis. 13:255-258.
29. Wray, C., R. W. Hedges, K. P. Shannon, and D. E. Bradley. 1986. Apramycin and gentamicin resistance in Escherichia coli and salmonellas isolated from farm animals. J. Hyg. (Lond.) 97:445-456.
30. Wulf, M. W., E. Tiemersma, J. Kluytmans, D. Bogaers, A. C. Leenders, M. W. Jansen, J. Berkhout, E. Ruijters, D. Haverkate, M. Isken, and A. Voss. 2008. MRSA carriage in healthcare personnel in contact with farm animals. J. Hosp. Infect. 70:186-190.
31. Yates, C. M., M. C. Pearce, M. E. Woolhouse, and S. G. Amyes. 2004. High frequency transfer and horizontal spread of apramycin resistance in calf faecal Escherichia coli. J. Antimicrob. Chemother. 54:534-537.
32. Zhang, X. Y., L. J. Ding, and M. Z. Fan. 2009. Resistance patterns and detection of aac(3)-IV gene in apramycin-resistant Escherichia coli isolated from farm animals and farm workers in northeastern of China. Res. Vet. Sci. 87:449-454.