Pathway analysis of Candida albicans survival and virulence determinants in a murine infection model

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 51, 2010, Pages 22044-22049

  Becker, Jeffrey M ^a   Kauffman, Sarah J ^a   Hauser, Melinda ^a   Huang, Liyin ^a   Lin, Molly ^b   Sillaots, Susan ^b   Jiang, Bo ^c   Xu, Deming ^b   Roemer, Terry ^b  

^a UNIVERSITY OF TENNESSEE   (United States)

^b MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^c GlycoFi Incorporated   (United States)

Author keywords

Animal model; Antifungal target; Conditional expression; Systemic candidiasis; Virulence factor

Indexed keywords

DOXYCYCLINE; DRINKING WATER; ERGOSTEROL; RIBOFLAVIN; TETRACYCLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANDIDA ALBICANS; CANDIDIASIS; ERG1 GENE; ERG11 GENE; ESSENTIAL GENE; FKS1 GENE; FUNGAL GENE; FUNGAL STRAIN; FUNGAL VIRULENCE; FUNGUS GROWTH; FUNGUS MUTANT; GENE EXPRESSION; GENE INACTIVATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; SURVIVAL;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CANDIDIASIS; DISEASE MODELS, ANIMAL; DOXYCYCLINE; DRUG DESIGN; ERGOSTEROL; FATTY ACIDS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; MICE; MICROBIAL VIABILITY; RIBOFLAVIN; VIRULENCE FACTORS;

ANIMALIA; CANDIDA ALBICANS; MURINAE;

EID: 78650648144     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1009845107     Document Type: Article

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