Development of the first inhaled antibiotic for the treatment of cystic fibrosis

Science Translational Medicine

Volumn 2, Issue 63, 2010, Pages

  Rose, Lynn M ^a,b   Neale, Richard ^c,d  

^a SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c SCRIPPS TRANSLATIONAL SCIENCE INSTITUTE   (United States)

^d SCRIPPS HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TOBRAMYCIN; ANTIINFECTIVE AGENT;

CONFERENCE PAPER; CYSTIC FIBROSIS; DRUG APPROVAL; DRUG EFFICACY; DRUG FORMULATION; DRUG INDUSTRY; DRUG MARKETING; DRUG RESEARCH; FOOD AND DRUG ADMINISTRATION; HUMAN; LUNG INFECTION; NATIONAL HEALTH ORGANIZATION; PATENT; PRIORITY JOURNAL; TOXICITY TESTING; TRANSLATIONAL RESEARCH; UNITED STATES; ARTICLE; INHALATIONAL DRUG ADMINISTRATION;

ADMINISTRATION, INHALATION; ANTI-BACTERIAL AGENTS; CYSTIC FIBROSIS; HUMANS; TOBRAMYCIN; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 78650634615     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3001634     Document Type: Conference Paper

References (2)

1. B. W. Ramsey, H. L. Dorkin, J. D. Eisenberg, R. L. Gibson, I. R. Harwood, R. M. Kravitz, D. V. Schidlow, R. W. Wilmott, S. J. Astley, M. A. McBurnie, K. Wentz, A. L. Smith, Efficacy of aerosolized tobramycin in patients with cystic fibrosis. N. Engl. J. Med. 328, 1740-1746 (1993).
2. B. W. Ramsey, M. S. Pepe, J. M. Quan, K. L. Otto, A. B. Montgomery, J. Williams-Warren, K. M. Vasiljev, D. Borowitz, C. M. Bowman, B. C. Marshall, S. Marshall, A. L. Smith, Intermittent administration of inhaled tobramycin in patients with cystic fibrosis. Cystic Fibrosis Inhaled Tobramycin Study Group. N. Engl. J. Med. 340, 23-30 (1999).