Impairment and functioning in a sample of primary care patients with generalized anxiety disorder: Results from the primary care anxiety project

Primary Care Companion to the Journal of Clinical Psychiatry

Volumn 12, Issue 5, 2010, Pages

  Weisberg, Risa B ^a   Beard, Courtney ^a   Pagano, Maria E ^b   Maki, Kristin M ^c   Culpepper, Larry ^d   Keller, Martin B ^a  

^a Department of Psychiatry and Human Behavior ^*  (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c Rhode Island Center for Cognitive Behavior Therapy Inc   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISEASE ASSOCIATION; FEMALE; FUNCTIONAL ASSESSMENT; FUNCTIONAL DISEASE; GENERALIZED ANXIETY DISORDER; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIMARY MEDICAL CARE; SHORT FORM 36; SOCIAL PSYCHOLOGY; STRUCTURED INTERVIEW; UNITED STATES;

EID: 78650622866     PISSN: 15235998     EISSN: 1555211X     Source Type: Journal    
DOI: 10.4088/PCC.09m00890blu     Document Type: Article

References (39)

1. Kessler RC, Berglund P, Demler O, et al. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005;62(6):593-602. PubMed doi:10.1001/archpsyc.62.6.593
2. Lépine JP. The epidemiology of anxiety disorders: prevalence and societal costs. J Clin Psychiatry. 2002;63(suppl 14):4-8. PubMed
3. Kessler RC, McGonagle KA, Zhao S, et al. Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States: results from the National Comorbidity Survey. Arch Gen Psychiatry. 1994;51(1):8-19. PubMed
4. Krasucki C, Howard R, Mann A. The relationship between anxiety disorders and age. Int J Geriatr Psychiatry. 1998;13(2):79-99. PubMed doi:10.1002/(SICI)1099-1166(199802)13:2<79::AID-GPS739>3.0.CO;2-G
5. Grant BF, Hasin DS, Stinson FS, et al. Prevalence, correlates, co-morbidity, and comparative disability of DSM-IV generalized anxiety disorder in the USA: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Psychol Med. 2005;35(12):1747-1759. PubMed doi:10.1017/S0033291705006069
6. Weisberg RB. Overview of generalized anxiety disorder: epidemiology, presentation, and course. J Clin Psychiatry. 2009;70(suppl 2):4-9. PubMed
7. Bruce SE, Yonkers KA, Otto MW, et al. Influence of psychiatric comorbidity on recovery and recurrence in generalized anxiety disorder, social phobia, and panic disorder: a 12-year prospective study. Am J Psychiatry. 2005;162:1179-1187. PubMed doi:10.1176/appi.ajp.162.6.1179
8. Blazer DG, Hughes D, George LK, et al. Generalized anxiety disorder. In: Robbins LN, Regier DA, eds. Psychiatric Disorders in America: The Epidemiologic Catchment Area Study. New York, NY: The Free Press; 1991:180-203.
9. Rodriguez BF, Weisberg RB, Pagano ME, et al. Characteristics and predictors of full and partial recovery from generalized anxiety disorder in primary care patients. J Nerv Ment Dis. 2006;194(2):91-97. PubMed doi:10.1097/01.nmd.0000198140.02154.32
10. Sanderson K, Andrews G. Prevalence and severity of mental health-related disability and relationship to diagnosis. Psychiatr Serv. 2002;53(1):80-86. PubMed doi:10.1176/appi.ps.53.1.80
11. Kessler RC, DuPont RL, Berglund P, et al. Impairment in pure and comorbid generalized anxiety disorder and major depression at 12 months in two national surveys. Am J Psychiatry. 1999;156(12):1915-1923. PubMed
12. Stein MB, Heimberg RG. Well-being and life satisfaction in generalized anxiety disorder: comparison to major depressive disorder in a community sample. J Affect Disord. 2004;79(1-3):161-166. PubMed doi:10.1016/S0165-0327(02)00457-3
13. Weiller E, Bisserbe JC, Maier W, et al. Prevalence and recognition of anxiety syndromes in five European primary care settings: a report from the WHO study on Psychological Problems in General Health Care. Br J Psychiatry suppl. 1998;34(34):18-23. PubMed
14. Boden JM, Fergusson DM, Horwood LJ. Anxiety disorders and suicidal behaviours in adolescence and young adulthood: findings from a longitudinal study. Psychol Med. 2007;37(3):431-440. PubMed doi:10.1017/S0033291706009147
15. Hoffman DL, Dukes EM, Wittchen HU. Human and economic burden of generalized anxiety disorder. Depress Anxiety. 2008;25(1):72-90. PubMed doi:10.1002/da.20257
16. Roy-Byrne PP. Generalized anxiety and mixed anxiety-depression: association with disability and health care utilization. J Clin Psychiatry. 1996;57(suppl 7):86-91. PubMed
17. Ormel J, VonKorff M, Ustun TB, et al. Common mental disorders and disability across cultures: results from the WHO Collaborative Study on Psychological Problems in General Health Care. JAMA. 1994;272(22):1741-1748. PubMed doi:10.1001/jama.272.22.1741
18. Schonfeld WH, Verboncoeur CJ, Fifer SK, et al. The functioning and well-being of patients with unrecognized anxiety disorders and major depressive disorder. J Affect Disord. 1997;43(2):105-119. PubMed doi:10.1016/S0165-0327(96)01416-4
19. Nisenson LG, Pepper CM, Schwenk TL, et al. The nature and prevalence of anxiety disorders in primary care. Gen Hosp Psychiatry. 1998;20(1):21-28. PubMed doi:10.1016/S0163-8343(97)00096-0
20. Tiemens BG, Ormel J, Simon GE. Occurrence, recognition, and outcome of psychological disorders in primary care. Am J Psychiatry. 1996;153(5):636-644. PubMed
21. Olfson M, Fireman B, Weissman MM, et al. Mental disorders and disability among patients in a primary care group practice. Am J Psychiatry. 1997;154(12):1734-1740. PubMed
22. Olfson M, Shea S, Feder A, et al. Prevalence of anxiety, depression, and substance use disorders in an urban general medicine practice. Arch Fam Med. 2000;9(9):876-883. PubMed doi:10.1001/archfami.9.9.876
23. Wittchen H-U, Kessler RC, Beesdo K, et al. Generalized anxiety and depression in primary care: prevalence, recognition, and management. J Clin Psychiatry. 2002;63(suppl 8):24-34. PubMed
24. Kroenke K, Spitzer RL, Williams JBW, et al. Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection. Ann Intern Med. 2007;146(5):317-325. PubMed
25. Jones GN, Ames SC, Jeffries SK, et al. Utilization of medical services and quality of life among low-income patients with generalized anxiety disorder attending primary care clinics. Int J Psychiatry Med. 2001;31(2):183-198. PubMed doi:10.2190/2X44-CR14-YHJC-9EQ3
26. Stein MB, Roy-Byrne PP, Craske MG, et al. Functional impact and health utility of anxiety disorders in primary care outpatients. Med Care. 2005;43(12):1164-1170. PubMed doi:10.1097/01.mlr.0000185750.18119.fd
27. Olfson M. Impairment in generalized anxiety disorder. Am J Psychiatry. 2000;157(12):2060-2061. PubMed doi:10.1176/appi.ajp.157.12.2060-b
28. Culpepper L. Generalized anxiety disorder in primary care: emerging issues in management and treatment. J Clin Psychiatry. 2002;63(suppl 8):35-42. PubMed
29. Spitzer RL, Kroenke K, Linzer M, et al. Health-related quality of life in primary care patients with mental disorders: results from the PRIME-MD 1000 study. JAMA. 1995;274(19):1511-1517. PubMed doi:10.1001/jama.274.19.1511
30. Ware JE Jr, Kosinski M. SF-36 Physical & Mental Health Summary Scales: A Manual for Users of Version 1. 2nd ed. Lincoln, RI: QualityMetric, Inc; 2005.
31. Hays RD, Wells KB, Sherbourne CD, et al. Functioning and well-being outcomes of patients with depression compared with chronic general medical illnesses. Arch Gen Psychiatry. 1995;52(1):11-19. PubMed
32. Thalji L, Haggerty CC, Rubin R, et al. 1990 National Survey of Functional Health Status: Final Report. Chicago, IL: NORC; 1991.
33. Weisberg RB, Bruce SE, Machan JT, et al. Nonpsychiatric illness among primary care patients with trauma histories and posttraumatic stress disorder. Psychiatr Serv. 2002;53(7):848-854. PubMed doi:10.1176/appi.ps.53.7.848
34. Weisberg RB, Dyck I, Culpepper L, et al. Psychiatric treatment in primary care patients with anxiety disorders: a comparison of care received from primary care providers and psychiatrists. Am J Psychiatry. 2007;164(2):276-282. PubMed doi:10.1176/appi.ajp.164.2.276
35. Weisberg RB, Maki KM, Culpepper L, et al. Is anyone really MAD? the occurrence and course of mixed anxiety-depressive disorder in a sample of primary care patients. J Nerv Ment Dis. 2005;193(4):223-230. PubMed doi:10.1097/01.nmd.0000158379.14063.cd
36. First MB, Sptizer RL, Gibbon M, et al. Structured Clinical Interview for the DSM-IV Axis I Disorders. New York, NY: Biometrics Research Department, New York State Psychiatric Institute; 1996.
37. Ware JE Jr, Sherbourne CD. The MOS 36-item Short-Form Health Survey (SF-36), I: conceptual framework and item selection. Med Care. 1992;30(6):473-483. PubMed doi:10.1097/00005650-199206000-00002
38. Cohen J. Statistical Power Analyses for the Behavioral Sciences. 2nd ed. Hillsdale, NJ: L. Erlbaum Associates; 1988.
39. Samsa G, Edelman D, Rothman ML, et al. Determining clinically important differences in health status measures: a general approach with illustration to the Health Utilities Index Mark II. Pharmacoeconomics. 1999;15(2):141-155. PubMed doi:10.2165/00019053-199915020-00003