Essential role of neutrophil mobilization in concanavalin A-induced hepatitis is based on classic IL-6 signaling but not on IL-6 trans-signaling

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1812, Issue 3, 2011, Pages 290-301

  Malchow, Sven ^a   Thaiss, Wolfgang ^a   Jänner, Nathalie ^a   Waetzig, Georg H ^b   Gewiese Rabsch, Jessica ^a   Garbers, Christoph ^a   Yamamoto, Kosuke ^a   Rose John, Stefan ^a   Scheller, Jürgen ^a,c  

^a UNIVERSITY OF KIEL   (Germany)

^b CONARIS Research Institute AG ^*  (Germany)

^c Department of Orthopedic Surgery   (Germany)

Author keywords

ConA; Hepatitis; Interleukin 6; Liver damage; Neutrophilia

Indexed keywords

CHEMOKINE; CONCANAVALIN A; INTERLEUKIN 4; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTROPHIL ATTRACTING CHEMOKINE KC; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; HEPATITIS; IMMUNE RESPONSE; LIVER INJURY; LIVER PROTECTION; MALE; MONOCYTE; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NEUTROPHILIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; BLOTTING, WESTERN; CHEMOKINE CCL2; CONCANAVALIN A; CYTOKINE RECEPTOR GP130; DRUG-INDUCED LIVER INJURY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOENZYME TECHNIQUES; INTERLEUKIN-6; LIVER; LIVER REGENERATION; MALE; MICE; MICE, INBRED C57BL; MITOGENS; NEUTROPHIL INFILTRATION; NEUTROPHILS; RECEPTORS, INTERLEUKIN-6; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

MUS;

EID: 78650588695     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2010.11.009     Document Type: Article

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