Emerging carbapenem resistance in the context of a new metallo-β-lactamase (NDM-1)

National Medical Journal of India

Volumn 23, Issue 5, 2010, Pages 261-262

  Basu, Sulagna ^a   Singh, Arun K ^b   Nair, G Balakrish ^a  

^a NATIONAL INSTITUTE OF CHOLERA AND ENTERIC DISEASES   (India)

^b Institute of Postgraduate Medical Education and Research and SSKM Hospital   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAPENEM; CARBAPENEMASE; METALLO BETA LACTAMASE;

ANTIBIOTIC RESISTANCE; BACTERIAL GENE; BACTERIAL TRANSMISSION; BACTERIAL VIRULENCE; BLA NDM 1 GENE; EDITORIAL; ESCHERICHIA COLI; HAND WASHING; HUMAN; INDIA; INFECTION CONTROL; KLEBSIELLA PNEUMONIAE; MEDICAL TOURISM; NEWBORN SEPSIS; NONHUMAN; PHYSICIAN ATTITUDE; PRESCRIPTION;

ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; CARBAPENEMS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; HUMANS; INDIA; MICROBIAL SENSITIVITY TESTS;

EID: 78650581943     PISSN: 0970258X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial

References (9)

1. Woodford N, Tierno PM Jr, Young K, Tysall L, Palepou MF, Ward E, et al. Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A β-lactamase, KPC-3, in a New York Medical Center. Antimicrob Agents Chemother 2004;48:4793-4799.
2. Queenan AM, Bush K. Carbapenemases: The versatile beta-lactamases. Clin Microbiol Rev 2007;20:440-458.
3. Yong D, Toleman MA, Giske CG, Cho HS, Sundman K, Lee K, et al. Characterization of a new metallo-beta-lactamase gene, bla (NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. Antimicrob Agents Chemother 2009;53:5046-5054.
4. Kumarasamy KK, Toleman MA, Walsh TR, Bagaria J, Butt F, Balakrishnan R, et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: A molecular, biological, and epidemiological study. Lancet Infect Dis 2010;10:597-602.
5. HPA. Health protection report. London:Health Protection Agency; 2009. Available at http://www.hpa.org.uk/hpr/archives/2009/Volume 3 Number 26 (accessed on 15 September 2010).
6. Pfeifer Y, Cullik A, Witte W. Resistance to cephalosporins and carbapenems in Gram-negative bacterial pathogens. Int J Med Microbiol 2010;300:371-379.
7. Högberg LD, Heddini A, Cars O. The global need for effective antibiotics: Challenges and recent advances. Trends Pharmacol Sci 2010; doi:10.1016/j.tips.2010.08.002
8. Kollef MH. Bench-to-bedside review: Antimicrobial utilization strategies aimed at preventing the emergence of bacterial resistance in the intensive care unit. Critical Care 2005;9:459-464.
9. Huovinen P, Cars O. Control of antimicrobial resistance: Time for action. BMJ 1998;317:613-614.