Antidiabetic and free radicals scavenging potential of Euphorbia hirta flower extract

Indian Journal of Pharmaceutical Sciences

Volumn 72, Issue 4, 2010, Pages 533-537

  Kumar, S ^a   Malhotra, R ^a   Kumar, D ^a  

^a KURUKSHETRA UNIVERSITY   (India)

Author keywords

Alloxan; antidiabetic; Euphorbia hirta; free radicals; mice; nitric oxide; superoxide

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ALKALINE PHOSPHATASE; ANTIDIABETIC AGENT; ANTIOXIDANT; ASCORBIC ACID; BUTYLATED HYDROXYANISOLE; CHOLESTEROL; CREATININE; EUPHORBIA EXTRACT; EUPHORBIA HIRTA EXTRACT; HIGH DENSITY LIPOPROTEIN; NITRIC OXIDE; SUPEROXIDE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UREA;

ALKALINE PHOSPHATASE BLOOD LEVEL; ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; EUPHORBIA; EUPHORBIA HIRTA; FLOWER; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; LIPOPROTEIN BLOOD LEVEL; MOUSE; NONHUMAN; TRIACYLGLYCEROL BLOOD LEVEL; UREA BLOOD LEVEL;

EID: 78650580096     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.73921     Document Type: Article

References (25)

1. Grover JK, Yadav S, Vats V. Medicinal plants of India with antidiabetic potential. J Ethnopharmacol 2002;81:81-100. (Pubitemid 34518472)
2. Rao BK, Kesavulu MM, Giri R, Rao CA. Antidiabetic and hypolipidemic effects of Momordica cymbalaria Hook: Fruit powder in alloxan diabetic rats. J Ethnopharmacol 1999;67:103-9. (Pubitemid 29389749)
3. Kamboj VP. Herbal medicine. Curr Sci 2000;78:35-51.
4. WHO Expert Committee on Diabetes Mellitus, Technical reports series. World Health Organisation, Geneva; 1980.
5. Rastogi RP, Mehrotra BN. Compendium of Indian Medicinal Plants. Vol. 4. New Delhi, India: National Institute of Science Communication; 2002. p. 310.
6. Hore SK, Ahuja V, Mehta G, Kumar P, Pandey SK, Ahmad AH. Effect of aqueous Euphorbia hirta leaf extract on gastrointestinal motility. Fitoterapia 2006;77:35-8. (Pubitemid 43011361)
7. Anonymous. The Wealth of India (Raw material). Vol. 4. New Delhi: Council of Industrial and Scientifi c Research; 2005. p. 113.
8. Sood SK, Bhardwaj R, Lakhanpal TN. Ethnic Indian Plants in cure of diabetes. Jodhpur, India: Scientifi c Publishers; 2005. p. 64-5.
9. Elizabeth MW. Major Herbs of Ayurveda. China: Churchill Livingstone; 2002. p. 141-4.
10. Isah AB, Ibrahim YK, Abdulrahman EM, Ibrahim MA. The hypoglycaemic Activity of the aqueous extract of Stachytarpheta angustifolia (Verbanaceae) in normoglycaemic and alloxan-induced diabetic rats. Pak J Biol Sci 2007;10:137-41.
11. Rifai N, Bachorik PS, Albers JJ. Lipids, lipoproteins and apolipoproteins. In: Burtis CA, Ashwood ER, editors. Tietz Textbook of Clinical Chemistry. 3rd ed. Philadelphia: WB Saunders Company; 1999. p. 809-61.
12. Burstein M, Scholnick HR, Morfi n R. Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions. J Lipid Res 1970;11:583-95.
13. Friedwald WT, Levy RJ, Fredricken DS. Estimation of HDL-C in the plasma without the use of preparative ultracentrifuge. Clin Chem 1972;18:449.
14. Tomas L. Clinical Laboratory Diagnostics. 1st ed. Frankfurt: TH-books Verlagsgesellschaft; 1998. p. 208-14.
15. Tomas L. Clinical Laboratory Diagnostics. 1st ed. Frankfurt: TH-books Verlagsgesellschaft; 1998. p. 366-74.
16. Tietz NW. Textbook of Clinical Chemisty. 3rd ed. Philadelphia: WB Saunders Company; 1986. p. 579.
17. Wilkinson JH, Boutwell JH, Winsten S. Evaluation of a new system for the kinetic measurement of serum alkaline phosphatase. Clin Chem 1969;15:487-95.
18. Sreejayan N, Rao MN. Free radical scavenging activity of curcuminoids. Drug Res 1996;46:169-71. (Pubitemid 26079147)
19. Nishikimi M, Rao NA, Yagi K. The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen. Biochem Biophys Res Commun 1972;46:849-53.
20. Ilhami GI, Haci AA, Mehmet C. Determination of In vitro antioxidant and radical scavenging activities of propofol. Chem Pharm Bull (Tokyo) 2005;53:281-5. (Pubitemid 40879897)
21. Govindarajan R, Rastogi S, Vijayakumar M. Studies on antioxidant activities of Desmodium gangeticum. Biol Pharm Bull 2003;26:1424-7. (Pubitemid 41685393)
22. Oyaizu M. Studies on product of browning reaction prepared from glucose amine. Jpn J Nutr 1986;44:307-15.
23. Mukherjee PK, Maiti K, Mukherjee K, Houghton PJ. Leads from Indian medicinal plants with hypoglycemic potentials. J Ethnopharmacol 2000;106:1-28.
24. Alarcon-Aguilara FJ, Roman-R amos R, Perez-Gutierrez S, Aguilar- Contreras A, Contreras- Weber CC, Flores-Saenz JL. Study of the antihyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-9. (Pubitemid 28297899)
25. Naziroglu M, Butterworth P. Protective effects of moderate exercise with dietary vitamin C and E on blood antioxidative defense mechanism in rats with streptozotocin-induced diabetes. Can J Appl Physiol 2005;30:172-85. (Pubitemid 40627541)