Predicting skin permeability from complex chemical mixtures: Dependency of quantitative structure permeation relationships on biology of skin model used

Toxicological Sciences

Volumn 119, Issue 1, 2011, Pages 224-232

  Riviere, Jim E ^a   Brooks, James D ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Chemical mixtures; In vitro models; Percutaneous dermal absorption; Pesticide risk assessment; QSPR; Quantitative structure activity relationships (QSAR); Skin permeability

Indexed keywords

4 NITROPHENOL; ALCOHOL; ARECAIDINE; ATRAZINE; CAFFEINE; CHEMICAL AGENT; CHLORPYRIFOS; CODEINE; DIMETHOATE; DIMPYLATE; DODECYL SULFATE SODIUM; FENTHION; HERBICIDE; METRIBUZIN; NITROPHENOL; OCTANOL; ORGANOPHOSPHATE; PROPAZINE; PROPYLENE GLYCOL; RICINOLEIC ACID; SIMAZINE; TESTOSTERONE; TRIAZINE; WATER;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CHEMICAL COMPOSITION; CORRELATION COEFFICIENT; DIFFUSION; EXPERIMENT; FEMALE; IN VITRO STUDY; NONHUMAN; QUANTITATIVE ANALYSIS; RISK ASSESSMENT; SKIN ABSORPTION; SKIN PERMEABILITY; STRUCTURE ACTIVITY RELATION; VALIDATION PROCESS;

SUS;

EID: 78650545496     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq317     Document Type: Article

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