Diphtheria-tetanus-pertussis vaccine administered simultaneously with measles vaccine is associated with increased morbidity and poor growth in girls. A randomised trial from Guinea-Bissau

Vaccine

Volumn 29, Issue 3, 2011, Pages 487-500

  Agergaard, J ^a,b   Nante, E ^a   Poulstrup, G ^a,c   Nielsen, J ^c   Flanagan, K L ^d   Ostergaard L ^b   Benn, C S ^c   Aaby, P ^a,c  

^a Studies of the Epidemiology of Epilepsy in Demographic Surveillance Systems   (Guinea-Bissau)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c STATENS SERUM INSTITUT   (Denmark)

^d MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

Author keywords

Diphtheria tetanus pertussis; Morbidity; Sex

Indexed keywords

DIPHTHERIA PERTUSSIS TETANUS VACCINE; MEASLES VACCINE; ORAL POLIOMYELITIS VACCINE;

ANTHROPOMETRY; APPETITE; ARM CIRCUMFERENCE; ARTICLE; BODY HEIGHT; BODY WEIGHT; CHILD; CONSULTATION; CRYING; DIARRHEA; DISEASE ASSOCIATION; DRUG ERUPTION; DRUG FEVER; FEMALE; GROWTH; GUINEA-BISSAU; HOSPITALIZATION; HUMAN; HYPOTHESIS; INFECTION; INJECTION SITE REACTION; MAJOR CLINICAL STUDY; MALE; MORBIDITY; PRESCHOOL CHILD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESTLESSNESS; RHINORRHEA; SEX DIFFERENCE; SIDE EFFECT; VACCINATION; VESICULAR RASH; VOMITING;

ANTHROPOMETRY; CHILD, PRESCHOOL; COMMUNICABLE DISEASES; DIPHTHERIA-TETANUS-PERTUSSIS VACCINE; FEMALE; GROWTH DISORDERS; GUINEA-BISSAU; HOSPITALIZATION; HUMANS; INFANT; MALE; MEASLES VACCINE; POLIOVIRUS VACCINE, ORAL; SEX FACTORS;

EID: 78650522805     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.10.071     Document Type: Article

References (38)

1. Aaby P., Samb B., Simondon F., Seck A.M., Knudsen K., Whittle H. Non-specific beneficial effect of measles immunisation: analysis of mortality studies from developing countries. BMJ 1995, 311((August) 7003):481-485.
2. Kristensen I., Aaby P., Jensen H. Routine vaccinations and child survival: follow up study in Guinea-Bissau, West Africa. BMJ 2000, 321((December) 7274):1435-1438.
3. Veirum J.E., Sodemann M., Biai S., Jakobsen M., Garly M.L., Hedegaard K., et al. Routine vaccinations associated with divergent effects on female and male mortality at the paediatric ward in Bissau, Guinea-Bissau. Vaccine 2005, 23((January) 9):1197-1204.
4. Aaby P., Jensen H., Rodrigues A., Garly M.L., Benn C.S., Lisse I.M., et al. Divergent female-male mortality ratios associated with different routine vaccinations among female-male twin pairs. Int J Epidemiol 2004, 33((April) 2):367-373.
5. Aaby P., Jensen H., Garly M.L., Bale C., Martins C., Lisse I. Routine vaccinations and child survival in a war situation with high mortality: effect of gender. Vaccine 2002, 21((November) 1-2):15-20.
6. Aaby P., Jensen H., Samb B., Cisse B., Sodemann M., Jakobsen M., et al. Differences in female-male mortality after high-titre measles vaccine and association with subsequent vaccination with diphtheria-tetanus-pertussis and inactivated poliovirus: reanalysis of West African studies. Lancet 2003, 361((June) 9376):2183-2188.
7. Aaby P., Jensen H., Gomes J., Fernandes M., Lisse I.M. The introduction of diphtheria-tetanus-pertussis vaccine and child mortality in rural Guinea-Bissau: an observational study. Int J Epidemiol 2004, 33((April) 2):374-380.
8. Aaby P., Biai S., Veirum J.E., Sodemann M., Lisse I., Garly M.L., et al. DTP with or after measles vaccination is associated with increased in-hospital mortality in Guinea-Bissau. Vaccine 2007, 25((January) 7):1265-1269.
9. Aaby P., Jensen H., Walraven G. Age-specific changes in the female-male mortality ratio related to the pattern of vaccinations: an observational study from rural Gambia. Vaccine 2006, 24((May) 22):4701-4708.
10. Aaby P., Ibrahim S.A., Libman M.D., Jensen H. The sequence of vaccinations and increased female mortality after high-titre measles vaccine: trials from rural Sudan and Kinshasa. Vaccine 2006, 24((April) 15):2764-2771.
11. Aaby P., Vessari H., Nielsen J., Maleta K., Benn C.S., Jensen H., et al. Sex differential effects of routine immunizations and childhood survival in rural Malawi. Pediatr Infect Dis J 2006, 25((August) 8):721-727.
12. Poulsen A., Qureshi K., Lisse I., Kofoed P.E., Nielsen J., Vestergaard B.F., et al. A household study of chickenpox in Guinea-Bissau: intensity of exposure is a determinant of severity. J Infect 2002, 45((November) 4):237-242.
13. RxList The Internet Drug Index. ; 2008. http://www.rxlist.com/dtp-drug.htm.
14. Simondon F., Yam A., Gagnepain J.Y., Wassilak S., Danve B., Cadoz M. Comparative safety and immunogenicity of an acellular versus whole-cell pertussis component of diphtheria-tetanus-pertussis vaccines in Senegalese infants. Eur J Clin Microbiol Infect Dis 1996, 15((December) 12):927-932.
15. ; 2009. http://www.who.int/childgrowth/en/.
16. Nielsen A.M., Larsen S.O., Zoffmann H. Whooping cough in Denmark among children under 1 year of age during 1980-1986. Ugeskr Laeger 1991, 153((May) 21):1482-1485.
17. Pasetti M., Eriksson P., Ferrero F., Manghi M. Serum antibodies to diphtheria-tetanus-pertussis vaccine components in Argentine children. Infection 1997, 25((November) 6):339-345.
18. Veirum J.E., Biai S., Jakobsen M., Sandstrom A., Hedegaard K., Kofoed P.E., et al. Persisting high hospital and community childhood mortality in an urban setting in Guinea-Bissau. Acta Paediatr 2007, 96((October) 10):1526-1530.
19. Benn C.S., Aaby P., Nielsen J., Binka F.N., Ross D.A. Does vitamin A supplementation interact with routine vaccinations? An analysis of the Ghana Vitamin A Supplementation Trial. Am J Clin Nutr 2009, 90((September) 3):629-639.
20. Benn C.S., Fisker A.B., Napirna B.M., Roth A., Diness B.R., Lausch K.R., et al. Vitamin A supplementation and BCG vaccination at birth in low birthweight neonates: two by two factorial randomised controlled trial. BMJ 2010, 340:c1101.
21. Lapidus N., Luquero F.J., Gaboulaud V., Shepherd S., Grais R.F. Prognostic accuracy of WHO growth standards to predict mortality in a large-scale nutritional program in Niger. PLoS Med 2009, 6((March) 3):e39.
22. UNICEF. ; 2007 December. http://www.unicef.org/progressforchildren/2007n6/index_41505.htm.
23. Fishman S., Caulfield L., Onis Mde, Blossner M., Hyder A., Mullany L., et al. Childhood and maternal underweight. In comparative quantification of health risks: global and regional burden of disease attributable to selected major risk factors. World Health Organ 2004, 1:39-162.
24. Benn C.S., Fisker A.B., Rodrigues A., Ravn H., Sartono E., Whittle H., et al. Sex-differential effect on infant mortality of oral polio vaccine administered with BCG at birth in Guinea-Bissau. A natural experiment. PLoS One 2008, 3(12):e4056.
25. Klein S. Host factors mediating sex differences in viral infection. Gend Med 2005, 2((December) 4):197-207.
26. Klein S.L. The effects of hormones on sex differences in infection: from genes to behavior. Neurosci Biobehav Rev 2000, 24((August) 6):627-638.
27. Klein S.L. Hormonal and immunological mechanisms mediating sex differences in parasite infection. Parasite Immunol 2004, 26((June) 6-7):247-264.
28. Casimir G.J., Mulier S., Hanssens L., Zylberberg K., Duchateau J. Gender differences in inflammatory markers in children. Shock 2010, 33((March) 3):258-262.
29. Klein S.L., Jedlicka A., Pekosz A. The Xs and Y of immune responses to viral vaccines. Lancet Infect Dis 2010, 10((May) 5):338-349.
30. Winter J.S., Hughes I.A., Reyes F.I., Faiman C. Pituitary-gonadal relations in infancy. 2. Patterns of serum gonadal steroid concentrations in man from birth to two years of age. J Clin Endocrinol Metab 1976, 42((April) 4):679-686.
31. Marriott I., Huet-Hudson Y.M. Sexual dimorphism in innate immune responses to infectious organisms. Immunol Res 2006, 34(3):177-192.
32. Fish E.N. The X-files in immunity: sex-based differences predispose immune responses. Nat Rev Immunol 2008, 8((September) 9):737-744.
33. Bland R.M., Rollins N.C., Van den B.J., Coovadia H.M. The use of non-prescribed medication in the first 3 months of life in rural South Africa. Trop Med Int Health 2004, 9((January) 1):118-124.
34. Deressa W., Ali A., Enqusellassie F. Self-treatment of malaria in rural communities, Butajira, southern Ethiopia. Bull World Health Organ 2003, 81(4):261-268.
35. Rodrigues A., Fischer T.K., Valentiner-Branth P., Nielsen J., Steinsland H., Perch M., et al. Community cohort study of rotavirus and other enteropathogens: are routine vaccinations associated with sex-differential incidence rates?. Vaccine 2006, 24((May) 22):4737-4746.
36. Valentiner-Branth P., Perch M., Nielsen J., Steinsland H., Garly M.L., Fischer T.K., et al. Community cohort study of Cryptosporidium parvum infections: sex-differential incidences associated with BCG and diphtheria-tetanus-pertussis vaccinations. Vaccine 2007, 25((March) 14):2733-2741.
37. Aaby P., Benn C.S. Assessment of childhood immunisation coverage. Lancet 2009, 373((April) 9673):1428.
38. Lim S.S., Stein D.B., Charrow A., Murray C.J. Tracking progress towards universal childhood immunisation and the impact of global initiatives: a systematic analysis of three-dose diphtheria, tetanus, and pertussis immunisation coverage. Lancet 2008, 372((December) 9655):2031-2046.