Flunarizine blocks voltage-gated Na+ and Ca2+ currents in cultured rat cortical neurons: A possible locus of action in the prevention of migraine

Neuroscience Letters

Volumn 487, Issue 3, 2011, Pages 394-399

  Ye, Qing ^a   Yan, Lan Yun ^a   Xue, Liu Jun ^a   Wang, Qiang ^b   Zhou, Zhi Kui ^a   Xiao, Hiang ^b   Wan, Qi ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Calcium current; Cortical neurons; Flunarizine; Migraine; Patch clamp recording; Sodium current

Indexed keywords

FLUNARIZINE; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN CORTEX; CALCIUM CURRENT; CHANNELOPATHY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; IC 50; INHIBITION KINETICS; MIGRAINE; NERVE CELL CULTURE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SODIUM CURRENT; STEADY STATE;

ANIMALS; CALCIUM CHANNEL BLOCKERS; CELLS, CULTURED; CEREBRAL CORTEX; FLUNARIZINE; ION CHANNEL GATING; MEMBRANE POTENTIALS; MIGRAINE DISORDERS; NEURONS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, VOLTAGE-GATED; RATS; SODIUM CHANNELS;

EID: 78650522516     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.10.064     Document Type: Article

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