Quantification of interactions between drug leads and serum proteins by use of "binding efficiency"

Analytical Biochemistry

Volumn 409, Issue 2, 2011, Pages 163-175

  Gustafsson, Sofia S ^a   Vrang, Lotta ^b   Terelius, Ylva ^b   Danielson, U Helena ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b MEDIVIR AB   (Sweden)

Author keywords

Binding efficiency; Biosensor; Human serum albumin (HSA); Serum protein; Surface plasmon resonance (SPR)

Indexed keywords

BINDING SITES; BIOSENSORS; EFFICIENCY; PLASMONS; PROTEINS; RATE CONSTANTS; SURFACE PLASMON RESONANCE;

ALPHA-1-ACID GLYCOPROTEIN; BINDING EFFICIENCY; HUMAN SERUM ALBUMINS; IDENTIFICATION OF STRUCTURES; INTERACTION MECHANISMS; KINETIC CHARACTERISTICS; SERUM PROTEINS; SURFACE PLASMON RESONANCE BIOSENSOR;

DRUG INTERACTIONS;

OROSOMUCOID; PLASMA PROTEIN; SERUM ALBUMIN;

ARTICLE; BINDING AFFINITY; BIOSENSOR; CATALYSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; STRUCTURE ACTIVITY RELATION; SURFACE PLASMON RESONANCE;

EID: 78650517490     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2010.10.028     Document Type: Article

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