메뉴 건너뛰기




Volumn 21, Issue 18, 2010, Pages 1162-1166

Retinoid X receptor α acts as a negative regulator in Nurr1-induced dopaminergic differentiation in rat neural precursor cells

Author keywords

Dopaminergic differentiation; Nurr1; Rat embryonic neural precursor cells; Retinoid X receptor

Indexed keywords

NUCLEAR RECEPTOR RELATED FACTOR 1; RETINOID X RECEPTOR ALPHA; RETROVIRUS VECTOR; TYROSINE 3 MONOOXYGENASE; DOPAMINE; NR4A2 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; GROWTH INHIBITOR; NR4A2 PROTEIN, RAT;

EID: 78650499719     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/WNR.0b013e328340ccf9     Document Type: Article
Times cited : (2)

References (20)
  • 1
    • 0038526314 scopus 로고    scopus 로고
    • Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors
    • Wang Z, Benoit G, Liu J, Prasad S, Aarnisalo P, Liu X, et al. Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors. Nature 2003; 423:555-560.
    • (2003) Nature , vol.423 , pp. 555-560
    • Wang, Z.1    Benoit, G.2    Liu, J.3    Prasad, S.4    Aarnisalo, P.5    Liu, X.6
  • 3
    • 0032980340 scopus 로고    scopus 로고
    • Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes
    • Wagner J, Akerud P, Castro DS, Holm PC, Canals JM, Snyder EY, et al. Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes. Nat Biotechnol 1999; 17:653-659.
    • (1999) Nat Biotechnol , vol.17 , pp. 653-659
    • Wagner, J.1    Akerud, P.2    Castro, D.S.3    Holm, P.C.4    Canals, J.M.5    Snyder, E.Y.6
  • 6
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • Mangelsdorf DJ, Evans RM. The RXR heterodimers and orphan receptors. Cell 1995; 83:841-850.
    • (1995) Cell , vol.83 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 7
    • 0025270737 scopus 로고
    • Nuclear receptor that identifies a novel retinoic acid response pathway
    • Mangelsdorf DJ, Ong ES, Dyck JA, Evans RM. Nuclear receptor that identifies a novel retinoic acid response pathway. Nature 1990; 345:224-229.
    • (1990) Nature , vol.345 , pp. 224-229
    • Mangelsdorf, D.J.1    Ong, E.S.2    Dyck, J.A.3    Evans, R.M.4
  • 8
    • 0037144573 scopus 로고    scopus 로고
    • Requirements for heterodimerization between the orphan nuclear receptor Nurr1 and retinoid X receptors
    • Sacchetti P, Dwornik H, Formstecher P, Rachez C, Lefebvre P. Requirements for heterodimerization between the orphan nuclear receptor Nurr1 and retinoid X receptors. J Biol Chem 2002; 277:35088-35096.
    • (2002) J Biol Chem , vol.277 , pp. 35088-35096
    • Sacchetti, P.1    Dwornik, H.2    Formstecher, P.3    Rachez, C.4    Lefebvre, P.5
  • 9
    • 0037144591 scopus 로고    scopus 로고
    • Defining requirements for heterodimerization between the retinoid X receptor and the orphan nuclear receptor Nurr1
    • Aarnisalo P, Kim CH, Lee JW, Perlmann T. Defining requirements for heterodimerization between the retinoid X receptor and the orphan nuclear receptor Nurr1. J Biol Chem 2002; 277:35118-35123.
    • (2002) J Biol Chem , vol.277 , pp. 35118-35123
    • Aarnisalo, P.1    Kim, C.H.2    Lee, J.W.3    Perlmann, T.4
  • 10
    • 0032584085 scopus 로고    scopus 로고
    • Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons
    • Saucedo-Cardenas O, Quintana-Hau JD, Le WD, Smidt MP, Cox JJ, De Mayo F, et al. Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons. Proc Natl Acad Sci U S A 1998; 95:4013-4018.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 4013-4018
    • Saucedo-Cardenas, O.1    Quintana-Hau, J.D.2    Le, W.D.3    Smidt, M.P.4    Cox, J.J.5    De Mayo, F.6
  • 11
    • 39649113551 scopus 로고    scopus 로고
    • Proneural bHLH neurogenin 2 differentially regulates Nurr1-induced dopamine neuron differentiation in rat and mouse neural precursor cells in vitro
    • Park CH, Kang JS, Yoon EH, Shim JW, Suh-Kim H, Lee SH. Proneural bHLH neurogenin 2 differentially regulates Nurr1-induced dopamine neuron differentiation in rat and mouse neural precursor cells in vitro. FEBS Lett 2008; 582:537-542.
    • (2008) FEBS Lett , vol.582 , pp. 537-542
    • Park, C.H.1    Kang, J.S.2    Yoon, E.H.3    Shim, J.W.4    Suh-Kim, H.5    Lee, S.H.6
  • 12
    • 0037660209 scopus 로고    scopus 로고
    • Orphan nuclear receptor Nurr1 directly transactivates the promoter activity of the tyrosine hydroxylase gene in a cell-specific manner
    • Kim KS, Kim CH, Hwang DY, Seo H, Chung S, Hong SJ, et al. Orphan nuclear receptor Nurr1 directly transactivates the promoter activity of the tyrosine hydroxylase gene in a cell-specific manner. J Neurochem 2003; 85:622-634.
    • (2003) J Neurochem , vol.85 , pp. 622-634
    • Kim, K.S.1    Kim, C.H.2    Hwang, D.Y.3    Seo, H.4    Chung, S.5    Hong, S.J.6
  • 13
    • 15544367211 scopus 로고    scopus 로고
    • Dopaminergic innervation of forebrain by ventral mesencephalon in organotypic slice co-cultures: Effects of GDNF
    • Jaumotte JD, Zigmond MJ. Dopaminergic innervation of forebrain by ventral mesencephalon in organotypic slice co-cultures: Effects of GDNF. Brain Res Mol Brain Res 2005; 134:139-146.
    • (2005) Brain Res Mol Brain Res , vol.134 , pp. 139-146
    • Jaumotte, J.D.1    Zigmond, M.J.2
  • 14
    • 33845599874 scopus 로고    scopus 로고
    • Acquisition of in vitro and in vivo functionality of Nurr1-induced dopamine neurons
    • Park CH, Kang JS, Shin YH, Chang MY, Chung S, Koh HC, et al. Acquisition of in vitro and in vivo functionality of Nurr1-induced dopamine neurons. FASEB J 2006; 20:2553-2555.
    • (2006) FASEB J , vol.20 , pp. 2553-2555
    • Park, C.H.1    Kang, J.S.2    Shin, Y.H.3    Chang, M.Y.4    Chung, S.5    Koh, H.C.6
  • 15
    • 70349857799 scopus 로고    scopus 로고
    • Generation of dopamine neurons with improved cell survival and phenotype maintenance using a degradation-resistant nurr1 mutant
    • Jo AY, Kim MY, Lee HS, Rhee YH, Lee JE, Baek KH, et al. Generation of dopamine neurons with improved cell survival and phenotype maintenance using a degradation-resistant nurr1 mutant. Stem Cells 2009; 27:2238-2246.
    • (2009) Stem Cells , vol.27 , pp. 2238-2246
    • Jo, A.Y.1    Kim, M.Y.2    Lee, H.S.3    Rhee, Y.H.4    Lee, J.E.5    Baek, K.H.6
  • 16
    • 5544325468 scopus 로고    scopus 로고
    • Nurr1, an orphan nuclear receptor with essential functions in developing dopamine cells
    • Perlmann T, Wallen-Mackenzie A. Nurr1, an orphan nuclear receptor with essential functions in developing dopamine cells. Cell Tissue Res 2004; 318:45-52.
    • (2004) Cell Tissue Res , vol.318 , pp. 45-52
    • Perlmann, T.1    Wallen-Mackenzie, A.2
  • 17
    • 0034650893 scopus 로고    scopus 로고
    • The coregulator exchange in transcriptional functions of nuclear receptors
    • Glass CK, Rosenfeld MG. The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev 2000; 14:121-141.
    • (2000) Genes Dev , vol.14 , pp. 121-141
    • Glass, C.K.1    Rosenfeld, M.G.2
  • 18
    • 0036835342 scopus 로고    scopus 로고
    • Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons
    • Chung S, Sonntag KC, Andersson T, Bjorklund LM, Park JJ, Kim DW, et al. Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons. Eur J Neurosci 2002; 16:1829-1838.
    • (2002) Eur J Neurosci , vol.16 , pp. 1829-1838
    • Chung, S.1    Sonntag, K.C.2    Andersson, T.3    Bjorklund, L.M.4    Park, J.J.5    Kim, D.W.6
  • 20
    • 33751000759 scopus 로고    scopus 로고
    • Multiple signaling pathways regulate the transcriptional activity of the orphan nuclear receptor NURR1
    • Sacchetti P, Carpentier R, Segard P, Olive-Cren C, Lefebvre P. Multiple signaling pathways regulate the transcriptional activity of the orphan nuclear receptor NURR1. Nucleic Acids Res 2006; 34:5515-5527.
    • (2006) Nucleic Acids Res , vol.34 , pp. 5515-5527
    • Sacchetti, P.1    Carpentier, R.2    Segard, P.3    Olive-Cren, C.4    Lefebvre, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.