An essential transcription factor, SciP, enhances robustness of Caulobacter cell cycle regulation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 44, 2010, Pages 18985-18990

  Tan, How Meng ^a   Kozdon, Jennifer B ^a,b   Shen, Xiling ^c   Shapiro, Lucy ^a   McAdams, Harley H ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

^c Cornell University   (United States)

Author keywords

CtrA; Feedback; Genetic circuit

Indexed keywords

BACTERIAL PROTEIN; CTRA PROTEIN; DNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ALPHAPROTEOBACTERIA; CAULOBACTER; CELL CYCLE; CELL CYCLE REGULATION; CELL GROWTH; CELL VIABILITY; CHEMOTAXIS; CONFERENCE PAPER; GENE; GENE CONTROL; GROWTH RATE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN MOTIF; PULSE RATE;

ALPHAPROTEOBACTERIA; CAULOBACTER;

EID: 78650495029     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1014395107     Document Type: Article

References (25)

1. McAdams HH, Shapiro L (2009) System-level design of bacterial cell cycle control. FEBS Lett 583:3984-3991.
2. Shen X, et al. (2008) Architecture and inherent robustness of a bacterial cell-cyclecontrol system. Proc Natl Acad Sci USA 105:11340-11345.
3. Laub MT, Shapiro L, McAdams HH (2007) Systems biology of Caulobacter. Annu Rev Genet 41:429-441.
4. Hottes AK, Shapiro L, McAdams HH (2005) DnaA coordinates replication initiation and cell cycle transcription in Caulobacter crescentus. Mol Microbiol 58:1340-1353.
5. Holtzendorff J, et al. (2004) Oscillating global regulators control the genetic circuit driving a bacterial cell cycle. Science 304:983-987.
6. McAdams HH, Shapiro L (2003) A bacterial cell-cycle regulatory network operating in time and space. Science 301:1874-1877.
7. Collier J, McAdams HH, Shapiro L (2007) A DNA methylation ratchet governs progression through a bacterial cell cycle. Proc Natl Acad Sci USA 104:17111-17116.
8. Collier J, Shapiro L (2007) Spatial complexity and control of a bacterial cell cycle. Curr Opin Biotechnol 18:333-340.
9. Laub MT, Chen SL, Shapiro L, McAdams HH (2002) Genes directly controlled by CtrA, a master regulator of the Caulobacter cell cycle. Proc Natl Acad Sci USA 99:4632-4637.
10. Brilli M, et al. (2010) The diversity and evolution of cell cycle regulation in alphaproteobacteria: A comparative genomic analysis. BMC Syst Biol 4:52.
11. Reisenauer A, Shapiro L (2002) DNA methylation affects the cell cycle transcriptionof the CtrA global regulator in Caulobacter. EMBO J 21:4969-4977.
12. McGrath PT, Iniesta AA, Ryan KR, Shapiro L, McAdams HH (2006) A dynamically localized protease complex and a polar specificity factor control a cell cycle master regulator.Cell 124:535-547.
13. Iniesta AA, McGrath PT, Reisenauer A, McAdams HH, Shapiro L (2006) A phosphosignaling pathway controls the localization and activity of a protease complex critical for bacterial cell cycle progression. Proc Natl Acad Sci USA 103:10935-19040.
14. Gora KG, et al. (2010) A cell-type-specific protein-protein interaction modulates transcriptional activity of a master regulator in Caulobacter crescentus. Mol Cell 39:455-467.
15. Domian IJ, Quon KC, Shapiro L (1997) Cell type-specific phosphorylation and proteolysis of a transcriptional regulator controls the G1-to-S transition in a bacterial cell cycle. Cell 90:415-424.
16. Jacobs C, Hung D, Shapiro L (2001) Dynamic localization of a cytoplasmic signal transduction response regulator controls morphogenesis during the Caulobacter cell cycle. Proc Natl Acad Sci USA 98:4095-4100
17. Quon KC, Marczynski GT, Shapiro L (1996) Cell cycle control by an essential bacterial two-component signal transduction protein. Cell 84:83-93.
18. McGrath PT, et al. (2007) High-throughput identification of transcription start sites, conserved promoter motifs and predicted regulons. Nat Biotechnol 25:584-592.
19. Rychlewski L, Jaroszewski L, Li W, Godzik A (2000) Comparison of sequence profiles.Strategies for structural predictions using sequence information. Protein Sci 9:232-241.
20. Jaroszewski L, Rychlewski L, Li Z, Li W, Godzik A (2005) FFAS03: A server for profile-profile sequence alignments. Nucleic Acids Res 33(web server issue):W284-W288.
21. Mangan S, Alon U (2003) Structure and function of the feed-forward loop network motif. Proc Natl Acad Sci USA 100:11980-11985.
22. Eichenberger P, et al. (2004) The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis. PLoS Biol 2:e328.
23. Mangan S, Itzkovitz S, Zaslaver A, Alon U (2006) The incoherent feed-forward loop accelerates the response-time of the gal system of Escherichia coli. J Mol Biol 356: 1073-1081.
24. Chen LS, Mullin D, Newton A (1986) Identification, nucleotide sequence, and controlof developmentally regulated promoters in the hook operon region of Caulobacter crescentus. Proc Natl Acad Sci USA 83:2860-2864.
25. Domian IJ, Reisenauer A, Shapiro L (1999) Feedback control of a master bacterial cellcycle regulator. Proc Natl Acad Sci USA 96:6648-6653.