Angiogenic activity of mesenchymal stem cells in multiple myeloma

Cancer Investigation

Volumn 29, Issue 1, 2011, Pages 37-41

  Wang, Xiaofang ^a   Zhang, Zhiqing ^b   Yao, Cheng ^c  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b Dalian Central Hospital   (China)

^c JILIN UNIVERSITY   (China)

Author keywords

Angiogenesis; BFGF; HGF; MSCs; Multiple myeloma; VEGF

Indexed keywords

ANGIOGENIC FACTOR; BASIC FIBROBLAST GROWTH FACTOR RECEPTOR; MESSENGER RNA; VASCULOTROPIN;

ADULT; ANGIOGENESIS; ARTICLE; CAPILLARY; CELL PROLIFERATION; CHEMOTAXIS; CONTROLLED STUDY; DONOR; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MESENCHYMAL STEM CELL; MULTIPLE MYELOMA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REAL TIME POLYMERASE CHAIN REACTION; RNA ANALYSIS; UMBILICAL VEIN;

ANGIOGENIC PROTEINS; CASE-CONTROL STUDIES; CELL MOVEMENT; CELL PROLIFERATION; CELL SEPARATION; CELL SURVIVAL; CELLS, CULTURED; CHEMOTAXIS; CULTURE MEDIA, CONDITIONED; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLAST GROWTH FACTOR 2; FLOW CYTOMETRY; HEPATOCYTE GROWTH FACTOR; HUMANS; MALE; MESENCHYMAL STEM CELLS; MIDDLE AGED; MULTIPLE MYELOMA; NEOPLASTIC STEM CELLS; NEOVASCULARIZATION, PHYSIOLOGIC; PARACRINE COMMUNICATION; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 78650491777     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.3109/07357907.2010.496758     Document Type: Article

References (14)

1. Ribatti D, Nico B, Vacca A. Importance of the bone marrow microenvironment in inducing the angiogenic response in multiple myeloma. Oncogene 2006;25:4257-4266.
2. Hideshima T, Mitsiades C, Tonon G, Richardson PG; Anderson KC. Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets. Nature Rev Cancer 2007;7:585-598.
3. Podar K, Tai YT, Davies FE, Lentzsch S, Sattler M, Hideshima T, Lin BK, Gupta D, Shima Y, Chauhan D, Mitsiades C, Raje N, Richardson P, Anderson KC. Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration. Blood 2001;98:428-435.
4. Iurlaro M, Vacca A,Minischetti M, Ribatti D, Pellegrino A, Sardanelli A, Giacchetta F, Dammacco F. Antiangiogenesis by cyclosporine. Exp Hematol 1998;26:1215-1222.
5. Vacca A, Iurlaro M, Ribatti D,Minischetti M, Nico B, Ria R, PellegrinoA, Dammacco F. Antiangiogenesis is produced by non-toxic doses of vinblastine. Blood 1999;94:4143-4155.
6. AliMA, Choy H,Habib AA, Saha D. SNS-032 prevents tumor cellinduced angiogenesis by inhibiting vascular endothelial growth factor. Neoplasia 2007;9:370-381.
7. Jakob C, Sterz J, Zavrski I, Heider U, Kleeberg L, Fleissner C, Kaiser M, Sezer O. Angiogenesis in multiplemyeloma. Eur J Cancer 2006;42:1581-1590.
8. Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR, ReyesM, Lenvik T, Lund T, Blackstad M, Du J, Aldrich S, Lisberg A, LowWC, Largaespada DA, Verfaillie CM. Pluripotency of mesenchymal stem cell derived from adult marrow. Nature 2002;418:41-49.
9. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak D.R. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284:143-147.
10. Kasten P, Vogel J, Luginbühl R, Niemeyer P,Weiss S, Schneider S, Kramer M, Leo A, Richter W. Influence of platelet-rich plasma on osteogenic differentiation of mesenchymal stem cells and ectopic bone formation in calcium phosphate ceramics. Cells Tissues Organs 2006;183:68-79. (Pubitemid 44610330)
11. Makino S, Fukuda K,Miyoshi S,Konishi F,Kodama H, Pan J, Sano M, Takahashi T, Hori S, Abe H, Hata J, Umezawa A, Ogawa S. Cardiomyocytes can be generated from marrow stromal cells in vitro. J Clin Invest 1999;103:697-705.
12. Zhao LR, DuanWM,ReyesM,Keene CD,VerfaillieCM, LowWC. Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats. Exp Neurol 2002;174:11-20.
13. Horwitz EM, Prockop DJ, Fitzpatrick LA, Koo WW, Gordon PL, Neel M, Sussman M, Orchard P, Marx JC, Pyeritz RE, Brenner MK. Transplantability and therapeutic effects of bone marrowderived mesenchymal cells in children with osteogenesis imperfecta. Nat Med 1999;5:309-313.
14. Arnulf B, Lecourt S, Soulier J, Ternaux B, Lacassagne MN, Crinquette A, Dessoly J, Sciaini AK, Benbunan M, Chomienne C, Fermand JP, Marolleau JP, Larghero J. Phenotypic and functional characterization of bone marrow mesenchymal stem cells derived from patients with multiple myeloma. Leukemia 2007;21:158-163.