Information integration: Its relevance to brain function and consciousness

Archives Italiennes de Biologie

Volumn 148, Issue 3, 2010, Pages 299-322

  Tononi, G ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Backconnections; Causality; Complexity; Degeneracy; Emergence; Matching; Qualia

Indexed keywords

ARTICLE; BIOLOGICAL MODEL; BRAIN; CONSCIOUSNESS; FEEDBACK SYSTEM; HUMAN; MENTAL FUNCTION; PHYSIOLOGY;

BRAIN; CONSCIOUSNESS; FEEDBACK, PHYSIOLOGICAL; HUMANS; MENTAL PROCESSES; MODELS, NEUROLOGICAL;

EID: 78650456096     PISSN: 00039829     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Alkire M.T., Hudetz A.G., Tononi G. Consciousness and anesthesia. Science, 322: 876-880, 2008.
2. Baars B.J. A Cognitive Theory of Consciousness. Cambridge, Cambridge University Press, 1988.
3. Bachmann T. Microgenetic approach to the conscious mind. Amsterdam, Philadelphia: John Benjamins Pub. Co, 2000.
4. Balduzzi D. and Tononi G. Integrated information in discrete dynamical systems: motivation and theoretical framework. PLoS Comput. Biol., 4: e1000091, 2008.
5. Balduzzi D. and Tononi G. Qualia: the geometry of integrated information. PLoS Comput. Biol., 5: e1000462, 2009.
6. Bateson G. Steps to an ecology of mind; collected essays in anthropology, psychiatry, evolution, and epistemology. San Francisco, Chandler Pub. Co., 1972.
7. Block N. Two neural correlates of consciousness. Trends. Cogn. Sci., 9: 46-52, 2005.
8. Blumenfeld H. and Taylor J. Why do seizures cause loss of consciousness? Neuroscientist, 9: 301-310, 2003.
9. Campbell D.T. 'Downward causation' in hierarchically organised biological systems. pp. 179-186. In: Dobzhansky F.J.A.T. (Ed.) Studies in the philosophy of biology, Berkeley, Los Angeles, University of California Press, 1974.
10. Cauller L. Layer I of primary sensory neocortex: where top-down converges upon bottom-up. Behav. Brain Res., 71: 163-170, 1995.
11. Cover T.M. and Thomas J.A. Elements of information theory. 2nd Edition. Hoboken, NJ, Wiley-Interscience, 2006.
12. Cowey A. and Walsh V. Magnetically induced phosphenes in sighted, blind and blindsighted observers. Neuroreport, 11: 3269-3273, 2000.
13. Crick F. and Koch C. A framework for consciousness. Nat. Neurosci., 6: 119-126, 2003.
14. Edelman G.M. and Mountcastle V.B. The mindful brain: cortical organization and the group-selective theory of higher brain function. Cambridge, MIT Press, 1978.
15. Ferrarelli F., Massimini M., Sarasso S., Casali A., Riedner B.A., Angelini G., Tononi G., Pearce R.A. Breakdown in cortical effective connectivity during midazolam-induced loss of consciousness. Proc. Natl. Acad. Sci. USA, 107: 2681-2686, 2010.
16. Gazzaniga M.S. Forty-five years of split-brain research and still going strong. Nat. Rev. Neurosci., 6: 653-659, 2005.
17. Hobson J.A., Pace-Schott E.F., Stickgold R. Dreaming and the brain: toward a cognitive neuroscience of conscious states. Behav. Brain Sci., 23: 793-842, 2000.
18. Hudetz A.G. Suppressing consciousness: Mechanisms of general anesthesia. Seminars in Anesthesia, Perioperative Medicine and Pain, 25: 196-204, 2006.
19. Imas O.A., Ropella K.M., Wood J.D., Hudetz A.G. Isoflurane disrupts anterio-posterior phase synchronization of flash-induced field potentials in the rat. Neurosci. Lett., 402: 216-221, 2006.
20. Jirsa V., Sporns O., Breakspear M., Deco G., McIntosh A.R. Towards the virtual brain: network modeling of the intact and the damaged brain. Arch. Ital. Biol., 2010 (this issue).
21. Koch C. The quest for consciousness: a neurobiological approach. Denver, CO., Roberts &Co., 2004.
22. Lamme V.A. Towards a true neural stance on consciousness. Trends Cogn. Sci., 10: 494-501, 2006.
23. Massimini M., Ferrarelli F., Huber R., Esser S.K., Singh H., Tononi G. Breakdown of cortical effective connectivity during sleep. Science, 309: 2228-2232, 2005.
24. Massimini M., Ferrarelli F., Esser S.K., Riedner B.A., Huber R., Murphy M., Peterson M.J., Tononi G. Triggering sleep slow waves by transcranial magnetic stimulation. Proc. Natl. Acad. Sci. USA, 104: 8496-8501, 2007.
25. Massimini M., Ferrarelli F., Murphy M.J., Huber R., Riedner B.A., Casarotto S., Tononi G. Cortical reactivity and effective connectivity during REM sleep in humans. Cogn. Neurosci., 2010, in press.
26. McIntosh A.R. Towards a network theory of cognition. Neural Netw., 13: 861-870, 2000.
27. McIntosh A.R., Kovacevic N., Lippe S., Garrett D., Grady C., Jirsa V. The development of a noisy brain. Arch. Ital. Biol., 2010 (this issue).
28. Milner A.D., Goodale M.A. The visual brain in action. New York, Oxford University Press, 1995.
29. Moruzzi G. and Magoun H.W. Brain stem reticular formation and activation of the EEG. Electroencephalog. Clin. Neurophysiol., 1: 455-473, 1949.
30. Owen A.M., Schiff N.D., Laureys S. A new era of coma and consciousness science. Prog. Brain Res., 177: 399-411, 2009.
31. Pascual-Leone A. and Walsh V. Fast backprojections from the motion to the primary visual area necessary for visual awareness. Science, 292: 510-512, 2001.
32. Perfetti B., Moisello C., Lanzafame S., Varanese S., Landsness E., Onofrj M., Di Rocco A., Tononi G., Ghilardi M.F. Attention modulation regulates both motor and non-motor performance: a high-density EEG study in Parkinson's disease. Arch. Ital. Biol., 2010 (this issue).
33. Pollen D.A. Fundamental requirements for primary visual perception. Cereb. Cortex, 18: 1991-1998, 2008.
34. Pöppel E. and Artin T. Mindworks: Time and conscious experience. Boston, MA, US, Harcourt Brace Jovanovich, Inc., 1988.
35. Price C.J., Crinion J.T., Leff A.P., Richardson F.M., Schofield T., Prejawa S., Ramsden S., Gazarian K., Lawrence M., Ambridge L., Andric M., Small S.L., Seghier M.L. Lesion sites that predict the ability to gesture how an object is used. Arch. Ital. Biol., 2010 (this issue).
36. Protzner A.B., Valiante T.A., Kovacevic N., McCormick C., McAndrews M.P. Hippocampal signal complexity in mesial temporal lobe epilepsy: a noisy brain is a healthy brain. Arch. Ital. Biol., 2010 (this issue).
37. Sarasso S., Santhanam P., Maatta S., Poryiazova R., Ferrarelli F., Tononi G., Small S. Non-fluent aphasia and neural reorganization after speech therapy: insights from human sleep electrophysiology. Arch. Ital. Biol., 2010 (this issue).
38. Schiff N., Ribary U., Plum F., Llinas R. Words without mind. J. Cogn. Neurosci., 11: 650-656, 1999.
39. Schwabe L., Obermayer K., Angelucci A., Bressloff P.C. The role of feedback in shaping the extra-classical receptive field of cortical neurons: a recurrent network model. J. Neurosci., 26: 9117-9129, 2006.
40. Shannon C.E. and Weaver W. The mathematical theory of communication. Urbana, University of Illinois Press, 1963.
41. Silvanto J., Cowey A., Lavie N., Walsh V. Striate cortex (V1) activity gates awareness of motion. Nat. Neurosci., 8: 143-144, 2005.
42. Sperry R.W. Mind-brain interaction: mentalism, yes; dualism, no. Neuroscience, 5: 195-206, 1980.
43. Szentagothai J. Downward causation? Annu. Rev. Neurosci., 7: 1-11, 1984.
44. Tononi G. Information measures for conscious experience. Arch. Ital. Biol., 139: 367-371, 2001.
45. Tononi G. An information integration theory of consciousness. BMC Neurosci., 5: 42, 2004.
46. Tononi G. Consciousness as integrated information: a provisional manifesto. Biol. Bull., 215: 216-242, 2008.
47. Tononi G. and Edelman G.M. Information: In the stimulus or in the context? Behav. Brain Sci., 20: 698-700, 1997.
48. Tononi G. and Laureys S. The Neurology of Consciousness: An Overview. pp. 375-412, In: Laureys S. and Tononi G. (Eds.) The Neurology of Consciousness, First Edition, Elsevier, 2009.
49. Tononi G., Sporns O., Edelman G.M. Reentry and the problem of integrating multiple cortical areas: simulation of dynamic integration in the visual system. Cereb. Cortex, 2: 310-335, 1992.
50. Tononi G., Sporns O., Edelman G.M. A complexity measure for selective matching of signals by the brain. Proc. Nat. Acad. Sci. USA, 93: 3422-3427, 1996.
51. Tononi G., Sporns O., Edelman G.M. Measures of degeneracy and redundancy in biological networks. Proc. Nat. Acad. Sci. USA, 96: 3257-3262, 1999.
52. Tononi G., McIntosh A.R., Russell D.P., Edelman G.M. Functional clustering: Identifying strongly interactive brain regions in neuroimaging data. Neuroimage, 7: 133-149, 1998.
53. Yourganov G., Schmah T., Small S.L., Rasmussen P.M., Strother P.M. Functional connectivity metrics during stroke recovery. Arch. Ital. Biol., 2010 (this issue).