Isolation of 2 new naphthablin analogs, JBIR-79 and JBIR-80, from Streptomyces sp. RI24

Journal of Antibiotics

Volumn 63, Issue 12, 2010, Pages 729-731

  Izumikawa, Miho ^a   Nagai, Aya ^a   Hashimoto, Junko ^a   Takagi, Motoki ^a   Shin Ya, Kazuo ^b  

^a Japan Biological Informatics Consortium   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; JBIR 79; JBIR 80; NAPHTHACENE DERIVATIVE; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG ISOLATION; FERMENTATION; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STREPTOMYCES; STRUCTURE ACTIVITY RELATION; ULTRAVIOLET SPECTROSCOPY;

CELL LINE; CELL SURVIVAL; FREE RADICAL SCAVENGERS; GLUTAMATES; HUMANS; NAPHTHOQUINONES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OPTICAL ROTATION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, INFRARED; SPECTROPHOTOMETRY, ULTRAVIOLET; STREPTOMYCES; TERPENES;

STREPTOMYCES SP.;

EID: 78650453291     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2010.120     Document Type: Article

References (12)

1. Choi, D. W. Cerebral hypoxia: some new approaches and unanswered questions. J. Neurosci. 10, 2493-2501 (1990).
2. Coyle, J. T. & Puttfarcken, P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 262, 689-695 (1993).
3. Kim, W. G. et al. New diphenazines with neuronal cell protecting activity, phenazostatins A and B, produced by Streptomyces sp. J. Antibiot. 50, 715-721 (1997).
4. Shin-ya, K., Shimizu, S., Kunigami, T., Furihata, K. & Seto, H. A new neuronal cell protecting substance, lavanduquinocin, produced by Streptomyces viridochromogenes. J. Antibiot. 48, 574-578 (1995).
5. Ueda, J.- Y., Hashimoto, J., Inaba, S., Takagi, M. & Shin-ya, K. JBIR-59, a new sorbicillinoid, from a marine-derived fungus Penicillium citrinum SpI080624G1f01. J. Antibiot. 63, 203-205 (2010).
6. Umezawa, K. et al. Isolation from Streptomyces of a novel naphthoquinone compound, naphthablin that inhibits Abl oncogene functions. J. Antibiot. 48, 604-607 (1995).
7. Hayakawa, M. & Nonomura, H. A new method for the intensive isolation of actinomy-cetes from soil. Actinomycetologica 3, 95-104 (1989).
8. Astill, B. D. & Roberts, C. J. Studies in mycological chemistry. Part I. Flaviolin, 2(or 3):5:7-trihydroxy-1:4-naphthaquinone, a metabolic product of Aspergillus citricus (Wehmer) mosseray. J. Chem. Soc. 3302-3307 (1953).
9. Shin-ya, K. et al. Isolation and structural elucidation of an antioxidative agent, naphterpin. J. Antibiot. 43, 444-447 (1990).
10. Wessels, P., Göhrt, A. & Zeeck, A. Metabolic products of microorganisms. 260. Naphthgeranines, new naphthoquinone antibiotics from Streptomyces sp. J. Antibiot. 44, 1013-1018 (1991).
11. Furihata, K. & Seto, H. Constant time HMBC (CT-HMBC), a new HMBC technique useful for improving separation of cross peaks. Tetrahedron Lett. 39, 7337-7340 (1998).
12. Kobayashi, M., Terui, Y., Tori, K. & Tsuji, N. Carbon-13 NMR spectra of juglone, naphthazarin and their derivatives. Te t r a h e d r o n L et t . 17, 619-620 (1976).