Enzyme-synthesized poly(amine-co-esters) as nonviral vectors for gene delivery

Journal of Biomedical Materials Research - Part A

Volumn 96 A, Issue 2, 2011, Pages 456-465

  Liu, Jie ^a,b   Jiang, Zhaozhong ^b   Zhou, Jiangbing ^b   Zhang, Shengmin ^a   Saltzman, W Mark ^b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Yale University   (United States)

Author keywords

cytotoxicity; enzyme catalyst; gene transfection; nonviral vector; poly(amine co esters)

Indexed keywords

ACIDIC CONDITIONS; CATIONIC POLYELECTROLYTE; CELLULAR UPTAKE; DIESTERS; DNA DELIVERY; ENZYME CATALYST; GENE CARRIER; GENE DELIVERY; GENE TRANSFECTION; IN-VITRO; IN-VIVO; LIPOFECTAMINE; NONVIRAL VECTORS; ONE STEP; POLY(AMINE-CO-ESTERS); POLYANIONICS; POLYPLEXES; PROTON SPONGE; TRANSFECTION EFFICIENCY;

CATALYSTS; COPOLYMERIZATION; COPOLYMERS; CYTOTOXICITY; DRUG THERAPY; ENZYMES; ESTERIFICATION; GENE THERAPY; GENE TRANSFER; NANOPARTICLES; VECTORS;

ESTERS;

LIPOFECTAMINE; LUCIFERASE; NANOPARTICLE; PLASMID DNA; POLY(AMINE CO ESTER) DERIVATIVE; POLY(N ETHYLDIETHYLENEAMINE SEBACATE); POLY(N METHYLDIETHYLENEAMINE SEBACATE); POLYAMINE DERIVATIVE; POLYELECTROLYTE; POLYETHYLENEIMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; POLYMERIZATION; PROTON TRANSPORT; SYNTHESIS;

ANIMALS; CELL DEATH; CELL LINE; CELL SURVIVAL; DNA; ESTERS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; LIPASE; LUCIFERASES; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; MOLECULAR WEIGHT; NANOPARTICLES; PLASMIDS; POLYAMINES; TRANSFECTION; VIRUSES;

EID: 78650445388     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32994     Document Type: Article

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