Patent foramen ovale is not associated with an increased risk of stroke recurrence

European Journal of Neurology

Volumn 17, Issue 11, 2010, Pages 1339-1345

  Feurer, R ^a   Sadikovic, S ^a   Sepp, D ^a   Esposito, L ^a   Schleef, M ^a   Bockelbrink, A ^b   Schwarze, J ^c   Hemmer, B ^a   Sander, D ^a   Poppert, H ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c KLINIKUM CHEMNITZ   (Germany)

Author keywords

Cardiac embolism; Right to left shunt; Stroke; Stroke in young adults; Transcranial doppler

Indexed keywords

ECHOVIST;

ADULT; ARTICLE; BRAIN ISCHEMIA; CARDIOVASCULAR RISK; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE ASSOCIATION; DOPPLER ECHOGRAPHY; FEMALE; FOLLOW UP; HEART INFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; NEUROIMAGING; OUTCOME ASSESSMENT; PARADOXICAL EMBOLISM; PATENT FORAMEN OVALE; PRIORITY JOURNAL; QUESTIONNAIRE; RECURRENCE RISK; RISK ASSESSMENT; RISK FACTOR; STROKE; VALSALVA MANEUVER;

ADULT; AGE FACTORS; AGED; COHORT STUDIES; ELECTROCARDIOGRAPHY; FEMALE; FORAMEN OVALE, PATENT; HEART RATE; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; NEUROLOGIC EXAMINATION; PLATELET AGGREGATION INHIBITORS; PROPORTIONAL HAZARDS MODELS; RECURRENCE; RESTLESS LEGS SYNDROME; RISK FACTORS; STROKE; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL;

EID: 78650428901     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2010.03015.x     Document Type: Article

References (22)

1. Lechat P, Mas JL, Lascault G, et al. Prevalence of patent foramen ovale in patients with stroke. N Engl J Med 1988; 318: 1148-1152.
2. Webster MW, Chancellor AM, Smith HJ, et al. Patent foramen ovale in young stroke patients. Lancet 1988; 2: 11-12.
3. Cabanes L, Mas JL, Cohen A, et al. Atrial septal aneurysm and patent foramen ovale as risk factors for cryptogenic stroke in patients less than 55 years of age. A study using transesophageal echocardiography. Stroke 1993; 24: 1865-1873.
4. Di Tullio M, Sacco RL, Gopal A, Mohr JP, Homma S. Patent foramen ovale as a risk factor for cryptogenic stroke. Ann Intern Med 1992; 117: 461-465.
5. Handke M, Harloff A, Olschewski M, Hetzel A, Geibel A. Patent foramen ovale and cryptogenic stroke in older patients. N Engl J Med 2007; 357: 2262-2268.
6. Meissner I, Khandheria BK, Heit JA, et al. Patent foramen ovale: innocent or guilty? Evidence from a prospective population-based study J Am Coll Cardiol 2006; 47: 440-445.
7. Di Tullio MR, Sacco RL, Sciacca RR, Jin Z, Homma S. Patent foramen ovale and the risk of ischemic stroke in a multiethnic population. J Am Coll Cardiol 2007; 49: 797-802.
8. Serena J, Marti-Fabregas J, Santamarina E, et al. Recurrent stroke and massive right-to-left shunt: results from the prospective Spanish multicenter (CODICIA) study. Stroke 2008; 39: 3131-3136.
9. Sacco RL, Adams R, Albers G, et al. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline. Circulation 2006; 113: e409-e449.
10. Bogousslavsky J, Garazi S, Jeanrenaud X, Aebischer N, Van Melle G. Stroke recurrence in patients with patent foramen ovale: the Lausanne Study. Lausanne Stroke with Paradoxal Embolism Study Group. Neurology 1996; 46: 1301-1305.
11. Mas JL, Arquizan C, Lamy C, et al. Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or both. N Engl J Med 2001; 345: 1740-1746.
12. Homma S, Di Tullio MR, Sacco RL, Sciacca RR, Smith C, Mohr JP. Surgical closure of patent foramen ovale in cryptogenic stroke patients. Stroke 1997; 28: 2376-2381.
13. Devuyst G, Bogousslavsky J, Ruchat P, et al. Prognosis after stroke followed by surgical closure of patent foramen ovale: a prospective follow-up study with brain MRI and simultaneous transesophageal and transcranial Doppler ultrasound. Neurology 1996; 47: 1162-1166.
14. Dearani JA, Ugurlu BS, Danielson GK, et al. Surgical patent foramen ovale closure for prevention of paradoxical embolism-related cerebrovascular ischemic events. Circulation 1999; 100: II171-II175.
15. Wahl A, Meier B, Haxel B, et al. Prognosis after percutaneous closure of patent foramen ovale for paradoxical embolism. Neurology 2001; 57: 1330-1332.
16. Poppert H, Morschhäuser M, Bockelbrink A, et al. Lack of association between right-to-left shunt and cerebral ischemia after adjustment for gender and age. J Negat Results Biomed 2008; 7: 7.
17. Schwarze JJ, Sander D, Kukla C, Wittich I, Babikian VL, Klingelhofer J. Methodological parameters influence the detection of right-to-left shunts by contrast transcranial Doppler ultrasonography. Stroke 1999; 30: 1234-1239.
18. Hagen PT, Scholz DG, Edwards WD. Incidence and size of patent foramen ovale during the first 10 decades of life: an autopsy study of 965 normal hearts. Mayo Clin Proc 1984; 59: 17-20.
19. Harmsen P, Lappas G, Rosengren A, Wilhelmsen L. Long-term risk factors for stroke: twenty-eight years of follow-up of 7457 middle-aged men in Goteborg, Sweden. Stroke 2006; 37: 1663-1667.
20. Homma S, Sacco RL, Di Tullio MR, Sciacca RR, Mohr JP. Effect of medical treatment in stroke patients with patent foramen ovale: patent foramen ovale in Cryptogenic Stroke Study. Circulation 2002; 105: 2625-2631.
21. Lamy C, Giannesini C, Zuber M, et al. Clinical and imaging findings in cryptogenic stroke patients with and without patent foramen ovale: the PFO-ASA Study. Atrial Septal Aneurysm. Stroke 2002; 33: 706-711.
22. Ranoux D, Cohen A, Cabanes L, Amarenco P, Bousser MG, Mas JL. Patent foramen ovale: is stroke due to paradoxical embolism? Stroke 1993; 24: 31-34.