Combination of gonadotropin-releasing hormone (GnRH) agonists with GnRH antagonists before chemotherapy reduce but does not completely prevent a follicle-stimulating hormone flare-up

Fertility and Sterility

Volumn 95, Issue 1, 2011, Pages 452-454

  Von Wolff, Michael ^a   Kämmerer, Ulrike ^b   Kollmann, Zahraa ^a   Santi, Alessandro ^a   Dietl, Johannes ^b   Frambach, Torsten ^b  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

Author keywords

cancer; chemotherapy; fertility; GnRH analogs; GnRH antagonists

Indexed keywords

ANTINEOPLASTIC AGENT; FOLLITROPIN; GONADORELIN AGONIST; GONADORELIN ANTAGONIST; GONADOTROPIN; LUTEINIZING HORMONE;

ADULT; ARTICLE; BREAST CANCER; CANCER CHEMOTHERAPY; CLINICAL ARTICLE; CRYOPRESERVATION; DRUG EFFICACY; DYSGERMINOMA; FEMALE; FEMALE FERTILITY; GLIOBLASTOMA; GRANULOMATOSIS; HODGKIN DISEASE; HUMAN; LEUKEMIA; LUPUS ERYTHEMATOSUS; NONHODGKIN LYMPHOMA; OVARY FUNCTION; PRIORITY JOURNAL; RANK SUM TEST;

ADULT; ANTINEOPLASTIC AGENTS; DRUG THERAPY, COMBINATION; ESTRADIOL; FEMALE; FERTILITY; FOLLICLE STIMULATING HORMONE; GONADOTROPIN-RELEASING HORMONE; HUMANS; INFERTILITY, FEMALE; LUTEINIZING HORMONE; NEOPLASMS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 78650419682     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2010.08.053     Document Type: Article

References (10)

1. M. von Wolff, J. Donnez, O. Hovatta, V. Keros, T. Maltaris, and M. Montag Cryopreservation and autotransplantation of human ovarian tissue prior to cytotoxic therapy - a technique in its infancy but already successful in fertility preservation Eur J Cancer 45 2009 1547 1553
2. M. von Wolff, C.J. Thaler, T. Frambach, C. Zeeb, B. Lawrenz, and R.M. Popovici Ovarian stimulation to cryopreserve fertilized oocytes in cancer patients can be started in the luteal phase Fertil Steril 92 2008 1360 1365
3. A. Badawy, A. Elnashar, M. El-Ashry, and M. Shahat Gonadotropin-releasing hormone agonists for prevention of chemotherapy-induced ovarian damage: prospective randomized study Fertil Steril 91 2009 694 697
4. A. Sverrisdottir, M. Nystedt, H. Johansson, and T. Fornander Adjuvant goserelin and ovarian preservation in chemotherapy treated patients with early breast cancer: results from a randomized trial Breast Cancer Res Treat 117 2009 561 567
5. L. Del Mastro, L. Boni, A. Michelotti, T. Gamucci, N. Olmeo, and M. Giordano Role of luteinizing hormone-releasing hormone analog (LHRHa) triptorelin (T) in preserving ovarian function during chemotherapy for early breast cancer patients: results of a multicenter phase III trial of Gruppo Italiano Mammella (GIM) group J Clin Oncol 28 2010 7s
6. K. Behringer, L. Wildt, H. Mueller, V. Mattle, P. Ganitis, B. van den Hoonaard on behalf of the German Hodgkin Study Group No protection of the ovarian follicle pool with the use of GnRH-analogues or oral contraceptives in young women treated with escalated BEACOPP for advanced-stage Hodgkin lymphoma. Final results of a phase II trial from the German Hodgkin Study Group Ann Oncol 2010 Mar 19. [Epub ahead of print]
7. T. Mardesic, M. Snajderova, L. Sramkova, P. Keslova, P. Sedlacek, and J. Stary Protocol combining GnRH agonists and GnRH antagonists for rapid suppression and prevention of gonadal damage during cytotoxic therapy Eur J Gynaecol Oncol 25 2004 90 92
8. C.L. Roth, L. Brendel, C. Rückert, and K. Hartmann Antagonistic and agonistic GnRH analogue treatment of precocious puberty: tracking gonadotropin concentrations in urine Horm Res 63 2005 257 262
9. A. Mueller, T. Maltaris, L. Häberle, I. Hoffmann, M.W. Beckmann, and R. Dittrich Pretreatment with gonadotropin-releasing hormone (GnRH) antagonists to prevent the flare-up effect of long-acting GnRH agonists: results of a pilot study Fertil Steril 91 2009 647 648
10. D.R. Danforth, L.K. Arbogast, and C.I. Friedman Acute depletion of murine primordial follicle reserve by gonadotropin-releasing hormone antagonists Fertil Steril 83 2005 1333 1338