A novel role for c-Jun N-terminal kinase and phosphoinositide 3-kinase in the liver X receptor-mediated induction of macrophage gene expression

Cellular Signalling

Volumn 23, Issue 3, 2011, Pages 542-549

  Huwait, Etimad A ^a   Greenow, Kirsty R ^a   Singh, Nishi N ^a   Ramji, Dipak P ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Apolipoprotein E; Atherosclerosis; ATP binding cassette tranporter A1; Gene expression; Liver X receptor; Macrophages; Signaling

Indexed keywords

22 HYDROXYCHOLESTEROL; 3 [3 [[2 CHLORO 3 (TRIFLUOROMETHYL)BENZYL](2 DIPHENYLETHYL)AMINO]PROPOXY]PHENYLACETIC ACID; ABC TRANSPORTER A1; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; APOLIPOPROTEIN E; CURCUMIN; LIVER X RECEPTOR ALPHA; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MACROPHAGE; PRIORITY JOURNAL; PROTEIN BINDING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ATP-BINDING CASSETTE TRANSPORTERS; CELLS, CULTURED; CHOLESTEROL; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MACROPHAGES; ORPHAN NUCLEAR RECEPTORS; PHOSPHATIDYLINOSITOL 3-KINASES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTIONAL ACTIVATION;

EID: 78650413890     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2010.11.002     Document Type: Article

References (29)

1. Bensinger S.J., Tontonoz P. Nature 2008, 454:470.
2. Beltowski J. J. Cardiovasc. Ther. 2008, 26:297.
3. Whitney K.D., Watson M.A., Goodwin B., Galardi C.M., Maglich J.M., Wilson J.G., Wilson T.M., Collins J.L., Kliewer S.A. J. Biol. Chem. 2001, 276:43509.
4. Tangirala R.K., Bischoff E.D., Joseph S.B., Wagner B.L., Walczak R., Lafitte B.A., Daige C.L., Thomas D., Heyman R.A., Mangelsdorf D.J., Wang X., Lusis A.J., Tontonoz P., Schulman I.G. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:11896.
5. Joseph S.B., McKilligin E., Pei L., Watson M.A., Collins A.R., Lafitte B.A., Chen M., Noh G., Goodman J., Hagger G.N., Tran J., Tippin T.K., Wang X., Lusis A.J., Hsueh W.A., Law R.E., Collins J.L., Willson T.M., Tontonoz P. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:7604.
6. Huuskonen J., Fielding P.E., Fielding C.J. Arterioscler. Thromb. Vasc. Biol. 2004, 24:703.
7. Burns K.A., van den Heuvel J.P. Biochim. Biophys. Acta 2007, 1771:952.
8. Greenow K., Pearce N.J., Ramji D.P. J. Mol. Med. 2005, 83:329.
9. Tall A.R., Yvan-Charvet L., Terasaka N., Pagler T., Wang N. Cell Metab. 2008, 7:365.
10. Li N., McLaren J.E., Michael D.R., Clement M., Fielding C.A., Ramji D.P. J. Immunol. 2010, 185:3041.
11. McLaren J.E., Calder C.J., McSharry B.P., Sexton K., Salter R.C., Singh N.N., Wilkinson G.W., Wang E.C., Ramji D.P. J. Immunol. 2010, 184:5827.
12. McLaren J.E., Michael D.R., Salter R.C., Ashlin T.G., Calder C.J., Miller A.M., Liew F.Y., Ramji D.P. J. Immunol. 2010, 185:1222.
13. Cham B.E., Knowles B.R. J. Lipid Res. 1976, 17:176.
14. Harvey E.J., Li N., Ramji D.P. Arterioscler. Thromb. Vasc. Biol. 2007, 27:806.
15. Ali S., Singh N.N., Yildirim H., Ramji D.P. Int. J. Biochem. Cell Biol. 2010, 42:113.
16. Irvine S.A., Foka P., Rogers S.A., Mead J.R., Ramji D.P. Nucleic Acids Res. 2005, 33:1423.
17. Auwerx J. Experienta 1991, 47:22.
18. Koldamova R.P., Lefterov I.M., Ikonomovic M.D., Skoko J., Lefterov P.I., Isanski B.A., Dekosky S.T., Lazo J.S. J. Biol. Chem. 2003, 278:13244.
19. Hayes M.M., Lane B.R., King S.R., Markovitz D.M., Coffey M.J. J. Biol. Chem. 2002, 277:16913.
20. Costet P., Lalanne F., Gerbod-Giannone M.C., Molina J.R., Fu X., Lund E.G., Gudras L.J., Tall A.R. Mol. Cell. Biol. 2003, 23:7756.
21. Singh N.N., Ramji D.P. Arterioscler. Thromb. Vascu. Biol. 2006, 26:1323.
22. Huang T.S., Lee S.C., Lin J.K. Proc. Natl. Acad. Sci. U. S. A. 1991, 88:5292.
23. Basheeruddin K., Rechtoris C., Mazzone T. Biochim. Biophys. Acta 1994, 1218:235.
24. Santamarina-Foji S., Pererson K., Knapper C., Qiu Y., Freeman L., Cheng J.F., Osorio J., Remaley A., Yang X.P., Haudenschild C., Prades C., Chimini G., Blackmon E., Francois T., Duverger N., Rubin E.M., Rosier M., Denéfle P., Fredrickson D.S., Brewer H.B. Proc. Natl. Acad. Sci. U. S. A. 2002, 97:7987.
25. Huang C.J., Feltkamo D., Nilsson S., Gustafsson J.A. Biochem. Biophys. Res. Commun. 1998, 243:657.
26. Yamamoto T., Shimano H., Inoue N., Nakagawa Y., Matsuzaka T., Takahashi A., Yahagi N., Sone H., Suzuki H., Toyoshima H., Yamada N. J. Biol. Chem. 2007, 282:11687.
27. Torra I.P., Ismaili N., Feig J.E., Xu C.-F., Cavasotto C., Pancratov R., Rogatsky I., Neubert T.A., Fisher E.A., Garabedian M.J. Mol. Cell. Biol. 2008, 28:2626.
28. Vicent G.P., Ballaré C., Nacht A.S., Clausell J., Subtil-Rodríguez A., Quiles I., Jordan A., Beato M. J. Steroid Biochem. Mol. Biol. 2008, 109:344.
29. Schmuth M., Elias P.M., Hanley K., Lau P., Moser A., Willson T.M., Bickle D.D., Feingold K.R. J. Invest. Dermatol. 2004, 123:41.