Vitamin D and the heart: Why we need large-scale clinical trials

Cleveland Clinic Journal of Medicine

Volumn 77, Issue 12, 2010, Pages 903-910

  Manson, Joann E ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OMEGA 3 FATTY ACID; VITAMIN; VITAMIN D;

ARTICLE; CARDIOVASCULAR DISEASE; DIET SUPPLEMENTATION; DRUG EFFECT; EVIDENCE BASED MEDICINE; HEART; HUMAN; METHODOLOGY; OBESITY; RISK ASSESSMENT; UNITED STATES; VITAMIN D DEFICIENCY;

CARDIOVASCULAR DISEASES; DIETARY SUPPLEMENTS; EVIDENCE-BASED MEDICINE; FATTY ACIDS, OMEGA-3; HEART; HUMANS; OBESITY; RESEARCH DESIGN; RISK ASSESSMENT; UNITED STATES; VITAMIN D; VITAMIN D DEFICIENCY; VITAMINS;

EID: 78650407634     PISSN: 08911150     EISSN: None     Source Type: Journal    
DOI: 10.3949/ccjm.77gr.10004     Document Type: Article

References (8)

1. Wang L, Manson JE, Song Y, Sesso HD. Systematic review: vitamin D and calcium supplementation in prevention of cardiovascular events. Ann Intern Med 2010; 152:315- 323.
2. Wang TJ, Pencina MJ, Booth SL, et al. Vitamin D deficiency and risk of cardiovascular disease. Circulation 2008; 117:503-511.
3. Giovannucci E, Liu Y, Hollis BW, Rimm EB. 25-Hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med 2008; 168:1174-1180.
4. Melamed ML, Michos ED, Post W, Astor B. 25-Hydroxyvitamin D levels and the risk of mortality in the general population. Arch Intern Med 2008; 168:1629-1637.
5. Autier P, Gandini S. Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. Arch Intern Med 2007; 167:1730-1737.
6. Trivedi DP, Doll R, Khaw KT. Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. BMJ 2003; 326:469.
7. Hsia J, Heiss G, Ren H, et al; Women's Health Initiative Investigators. Calcium/vitamin D supplementation and cardiovascular events. Circulation 2007; 115:846-854.
8. LaCroix AZ, Kotchen J, Anderson G, et al. Calcium plus vitamin D supplementation and mortality in postmenopausal women: the Women's Health Initiative calcium-vitamin D randomized controlled trial. J Gerontol A Biol Sci Med Sci 2009; 64:559-567.