Adenosine augmentation therapy for epilepsy

Epilepsia

Volumn 51, Issue SUPPL. 5, 2010, Pages 97-

  Boison, Detlev ^a  

^a LEGACY RESEARCH   (United States)

Author keywords

Adenosine kinase; Adenosine releasing polymers; Anticonvulsant; Astrogliosis; RNA interference; Seizures; Stem cells

Indexed keywords

ADENOSINE; ADENOSINE A1 RECEPTOR AGONIST; POLYMER;

ARTICLE; BRAIN REGION; DRUG EFFICACY; EPILEPSY; HUMAN; MESENCHYMAL STEM CELL; PRIORITY JOURNAL; RNA INTERFERENCE; STEM CELL;

EID: 78650407542     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2010.02883.x     Document Type: Article

References (3)

1. Li T, Ren G, Lusardi T, Wilz A, Lan JQ, Iwasato T, Itohara S, Simon RP, Boison D,. (2008) Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice. J Clin Inv 118: 571-582.
2. Ren G, Li T, Lan JQ, Wilz A, Simon RP, Boison D,. (2007) Lentiviralrnai-induced downregulation of adenosine kinase in human mesenchymal stem cell grafts: a novel perspective for seizure control. Exp Neuro 208: 26-37.
3. Studer FE, Fedele DE, Marowsky A, Schwerdel C, Wernli K, Vogt K, Fritschy J-M, Boison D,. (2006) Shift of adenosine kinase expression from neurons to astrocytes during postnatal development suggests dual functionality of the enzyme. Neuroscience 142: 125-137.