Presumptive Nocardia spp. Infection in a dog treated with cyclosporin and ketoconazole

New Zealand Veterinary Journal

Volumn 58, Issue 5, 2010, Pages 265-268

  Paul, A E H ^a   Mansfield, C S ^a   Thompson, M ^b  

^a MURDOCH UNIVERSITY   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Cyclosporin; Dog; Nocardia spp.; Spinal cord

Indexed keywords

ANTIFUNGAL AGENT; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; KETOCONAZOLE;

ANIMAL; ANIMAL DISEASE; ARTICLE; ATOPIC DERMATITIS; CASE REPORT; DOG; FEMALE; IMMUNOSUPPRESSIVE TREATMENT; ISOLATION AND PURIFICATION; MICROBIOLOGY; NOCARDIA; NOCARDIOSIS; OPPORTUNISTIC INFECTION;

ANIMALS; ANTIFUNGAL AGENTS; CYCLOSPORINE; DERMATITIS, ATOPIC; DOGS; FEMALE; IMMUNOSUPPRESSION; IMMUNOSUPPRESSIVE AGENTS; KETOCONAZOLE; NOCARDIA; NOCARDIA INFECTIONS; OPPORTUNISTIC INFECTIONS;

ANIMALIA; CANIS FAMILIARIS; NOCARDIA; POSIBACTERIA;

EID: 78650406498     PISSN: 00480169     EISSN: 11760710     Source Type: Journal    
DOI: 10.1080/00480169.2010.69301     Document Type: Article

References (41)

1. Adamo PF, H Rylander, Adams WM. Ciclosporin use in multi-drug therapy for meningoencephalomyelitis of unknown aetiology in dogs. Journal of Small Animal Practice 48, 486-96, 2007
2. Albengres E, Tillement JP. Cyclosporin and ketoconazole drug interaction or therapeutic association? International Journal of Clinical Pharmacology, Therapy and Toxicology 30, 555-70, 1992
3. Beaman BL. The possible role of L-phase variants of Nocardia in chronic infections. Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene Abstrakt 1 (Supplement 11), 221-7, 1981
4. Beaman BL. The cell wall as a determinant of pathogenicity in Nocardia: the role of L-forms in pathogenesis. In: Ortiz-Ortiz L, Bojalil LF, Yakoleff V (eds). Biological, Biochemical and Biomedical Aspects of Actinomycetes. Pp 89-105. Academic Press, Orlando FL, USA, 1984
5. Beaman BL. The biology of cell wall defective forms of Nocardia. In: Madoff S (ed). The Bacterial L-forms. Pp 203-27. Marcel Dekker Inc, New York, USA, 1986
6. Beaman BL, Beaman L. Nocardia species: host-parasite relationships. Clinical Microbiology Reviews 7, 213-64, 1994
7. Beaman BL, Smathers M. Interaction of Nocardia asteroides with cultured rabbit alveolar macrophages. Injection and Immunity 13, 1126-31, 1976
8. Beaman BL, Gershwin ME, Maslan S. Infectious agents in immunodeficient murine models: pathogenicity of Nocardia asteroides in congenitally athymic (nude) and hereditary asplenic (Dh/+) mice. Infection and Immunity 20, 381-7, 1978 a
9. Beaman BL, Goldstein BE, Gershwin ME, Maslan S, Lippert W. Lung response in congenitally athymic (nude) heterozygous and Swiss Webster mice to aerogenic and intranasal infection of Nocardia asteroides. Infection and Immunity 22, 867-77, 1978 b
10. Berkey P, Moore D, Rolston K. In vitro susceptibilities of Nocardia species to newer antimicrobial agents. Antimicrobial Agents and Chemotherapy 32, 1078-9, 1988
11. Bishop PJ, Neuman G. The history of the Ziehl-Neelson stain. Tubercle 51, 196-206, 1970
12. Bourgeois L, Beaman BL. Probable L-forms of Nocardia asteroides induced in cultured mouse peritoneal macrophages. Infection and Immunity 9, 576-90, 1974
13. Corti ME, Villafañe Fioti ME. Nocardiosis: a review. International Journal of Infectious Diseases 7, 243-50, 2003
14. Dahlinger J, Gregort C, Bea J. Effect of ketoconazole on cyclosporine A and ketoconazole treatment of anal furunculosis Veterinary Surgery 27, 64-8, 1998
15. Deem RL, Doughty FA, Beaman BL. Immunologically specific direct T lymphocyte-mediated killing of Nocardia asteroides. Journal of Immunology 130,2401-6, 1983
16. Domingue GJ, Woody HB. Bacterial persistence and expression of disease. Clinical Microbiology Reviews 10, 320-44, 1997
17. Durmaz R, Atasoy MA, Durmaz G, Adapinar B, Arslantas A, Aydinli A, Tel E. Multiple nocardial abscesses of cerebrum, cerebellum and spinal cord, causing quadriplegia. Clinical Neurology and Neurosurgery 103, 59-62, 2001
18. Fontaine J, Olivry T. Treatment of canine atopic dermatitis with cyclosporine: a pilot clinical study. Veterinary Record 148, 662-3, 2001
19. Greene CE, Cook JR, Mahaffey EA. Clindamycin for treatment of Toxoplasma polymyositis in a dog. Journal of the American Veterinary Medical Association 187, 631-3, 1985
20. Guagere E, Steffan J, Olivry T. Cyclosporin A: a new drug in the field of canine dermatology. Veterinary Dermatology 15, 61-74, 2004
21. Harari J, Lincoln J. Pharmacologic features of clindamycin in dogs and cats. Journal of the American Veterinary Medical Association 195, 124-125, 1989
22. Hay WH, Shell LG, Lindsay DS. Diagnosis and treatment of Neospora caninum infection in a dog. Journal of the American Veterinary Medical Association 197, 87-9, 1990
23. Kadar E, Sykes, JF, Kass PH, Bernsteen L, Gregory CR, Kyles AE. Evaluation of the prevalence of infections in cats after renal transplantation: 169 cases (1987-2003). Journal of the American Veterinary Medical Association 227, 948-53, 2005
24. Kobayashi T, Momoi Y, Iwasaki T. Cyclosporine A inhibits the mRNA expressions of IL-2, IL-4 and IFN-y, but not TNF-a, in canine mononuclear cells. Journal of Veterinary Medical Science 69, 887-92, 2007
25. Mok CC, Lau CS, Poon SP. Primary nocardial meningitis in systemic lupus erythematosus. British Journal of Rheumatology 34, 178-81, 1995
26. Mouatt JG. Cyclosporin and ketoconazole interaction for treatment of perianal fistulas in the dog. Australian Veterinary Journal 80, 207-11, 2002
27. Olivry T, Rivierre C, Jackson HA. Cyclosporine decreases skin lesions and pruritis in dogs with atopic dermatitis: a blinded randomized prednisolone-controlled trial. Veterinary Dermatology 13, 77-87, 2002 a
28. Olivry T, Steffan J, Fisch RD. Randomized controlled trial of the efficacy of cyclosporine in the treatment of atopic dermatitis in dogs. Journal of the American Veterinary Medical Association 221, 370-7, 2002 b
29. O’Neill T, Edwards GA, Holloway S. Efficacy of combined cyclosporine A and ketoconazole treatment on anal furunculosis. Journal of Small Animal Practice 45, 238-43 2004
30. Onuma K, Crespo MM, Dauber JH, Rubin JT, Sudilovsky D. Disseminated nocardiosis diagnosed by fine needle aspiration biopsy: Quick and accurate diagnostic approach. Diagnostic Cytopathology 34, 768-71, 2006
31. Radowicz SN, Power HT. Long-term use of cyclosporine in the treatment of canine atopic dermatitis. Veterinary Dermatology 16, 81-6, 2005
32. Robson D. Review of the pharmacokinetics, interactions and adverse reactions of cyclosporine in people, dogs and cats. Veterinary Record 152, 739-48, 2003
33. Rosenkrantz WS, Griffin CE, Barr RJ. Clinical evaluation of cyclosporine in animal models with cutaneous immune-mediated disease and epitheliotropic lymphoma. Journal of the American Animal Hospital Association 250, 377-84, 1989
34. Selby R, Ramirez CB, Singh R, Kleopoulos I, Kusne S, Starzl TE, Fung J. Brain abscess in solid organ transplant recipients receiving cyclosporine-based immunosuppresion. Archives of Surgery 132, 304-10, 1997
35. Shawar RM, Moore DG, LaRocco MT. Cultivation of Nocardia spp on chemically defined media for selective recovery of isolates from clinical specimens. Journal of Clinical Microbiology 28, 508-12, 1990
36. Siebel W Sundberg JP, Lesko LJ, Sauk JJ, McCleary LB, Hassell TM. Cutaneous papillomatous hyperplasia in cyclosporine-A-treated beagles. Journal of Investigative Dermatology 93, 224-30, 1989
37. Smith PM, Haughland SP, Jeffery ND. Brain abscess in a dog immunosuppressed using cyclosporin. Veterinary Journal 173, 675-8, 2007
38. Steffan J, Strehlau G, Maurer, M Rohlfs A. Cyclosporin A pharmacokinetics and efficacy in the treatment of atopic dermatitis in dogs. Journal ofVeterinary Pharmacology and Therapeutics 27, 231-8, 2004
39. Steffan J, Parks C, Seewald W. Clinical trial evaluating the efficacy and safety of cyclosporine in dogs with atopic dermatitis. Journal of the American Veterinary Medical Association 226, 1855-63, 2005
40. Venkatakrishnan K, Von Moltke LL, Greenblatt DJ. Effects of the antifungal agents on oxidative drug metabolism: clinical relevance. Clinical Pharmacokinetics 38, 111-80, 2000
41. Zaatreh M, Alabulkarim W. Images in clinical medicine: Disseminated central nervous system nocardiosis. New England Journal of Medicine 354, 2802, 2006