Contribution of CmeG to antibiotic and oxidative stress resistance in Campylobacter jejuni

Journal of Antimicrobial Chemotherapy

Volumn 66, Issue 1, 2011, Pages 79-85

  Jeon, Byeonghwa ^a,d   Wang, Yang ^a,b   Hao, Haihong ^a,c   Barton, Yi Wen ^a   Zhang, Qijing ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b CHINA AGRICULTURAL UNIVERSITY   (China)

^c HUAZHONG AGRICULTURAL UNIVERSITY   (China)

^d UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

Author keywords

Antibiotic resistance; C. jejuni; Efflux pumps

Indexed keywords

CEFOTAXIME; CHOLIC ACID; CIPROFLOXACIN; ENROFLOXACIN; ERYTHROMYCIN; ETHIDIUM BROMIDE; GENTAMICIN; HYDROGEN PEROXIDE; LEVOFLOXACIN; MOXIFLOXACIN; NORFLOXACIN; POLYMYXIN B; RIFAMPICIN; STREPTOMYCIN; TETRACYCLINE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL MUTATION; BACTERIUM MUTANT; CAMPYLOBACTER JEJUNI; CMEG GENE; CONTROLLED STUDY; GENE INACTIVATION; GENE OVEREXPRESSION; GENE SEQUENCE; GENOME ANALYSIS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; MUTAGENESIS; NONHUMAN; OXIDATIVE STRESS; SHUTTLE VECTOR; WILD TYPE;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CAMPYLOBACTER JEJUNI; DRUG RESISTANCE, BACTERIAL; ETHIDIUM; GENE DELETION; GENE EXPRESSION; GENETIC VECTORS; HUMANS; HYDROGEN PEROXIDE; MEMBRANE TRANSPORT PROTEINS; MICROBIAL SENSITIVITY TESTS; MUTAGENESIS, INSERTIONAL; OXIDATIVE STRESS; STRESS, PHYSIOLOGICAL;

EID: 78650381828     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkq418     Document Type: Article

References (37)

1. Friedman CR, Neimann J, Wegener HC et al. Epidemiology of Campylobacter jejuni infections in the United States and other industrialized nations. In: Nachamkin I, Blaser MJ, eds. Campylobacter. Washington, DC, USA: ASM Press, 2000; 121-38.
2. Allos BM. Campylobacter jejuni infections: update on emerging issues and trends. Clin Infect Dis 2001; 32: 1201-6.
3. Engberg J, Aarestrup FM, Taylor DE et al. Quinolone and macrolide resistance in Campylobacter jejuni and C. coli: resistance mechanisms and trends in human isolates. Emerg Infect Dis 2001; 7: 24-34.
4. Gibreel A, Kos VN, Keelan M et al. Macrolide resistance in Campylobacter jejuni and Campylobacter coli: molecular mechanism and stability of the resistance phenotype. Antimicrob Agents Chemother 2005; 49: 2753-9.
5. Poole K. Efflux-mediated antimicrobial resistance. J Antimicrob Chemother 2005; 56: 20-51.
6. Putman M, van Veen HW, Konings WN. Molecular properties of bacterial multidrug transporters. Microbiol Mol Biol Rev 2000; 64: 672-93.
7. Poole K. Outer membranes and efflux: the path to multidrug resistance in Gram-negative bacteria. Curr Pharm Biotechnol 2002; 3: 77-98.
8. Chen H, Hu J, Chen PR et al. The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism. Proc Natl Acad Sci USA 2008; 105: 13586-91.
9. Palma M, Zurita J, Ferreras JA et al. Pseudomonas aeruginosa SoxR does not conform to the archetypal paradigm for SoxR-dependent regulation of the bacterial oxidative stress adaptive response. Infect Immun 2005; 73: 2958-66.
10. Ramon-Garcia S, Martin C, Thompson CJ et al. Role of the Mycobacterium tuberculosis P55 efflux pump in intrinsic drug resistance, oxidative stress responses, and growth. Antimicrob Agents Chemother 2009; 53: 3675-82.
11. Santiviago CA, Fuentes JA, Bueno SM et al. The Salmonella enterica sv. Typhimurium smvA, yddG and ompD (porin) genes are required for the efficient efflux of methyl viologen. Mol Microbiol 2002; 46: 687-98.
12. Akiba M, Lin J, Barton YW et al. Interaction of CmeABC and CmeDEF in conferring antimicrobial resistance and maintaining cell viability in Campylobacter jejuni. J Antimicrob Chemother 2006; 57: 52-60.
13. Lin J, Michel LO, Zhang Q. CmeABC functions as a multidrug efflux system in Campylobacter jejuni. Antimicrob Agents Chemother 2002; 46: 2124-31.
14. Lin J, Sahin O, Michel LO et al. Critical role of multidrug efflux pump CmeABC in bile resistance and in vivo colonization of Campylobacter jejuni. Infect Immun 2003; 71: 4250-9.
15. Parkhill J, Wren BW, Mungall K et al. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences. Nature 2000; 403: 665-8.
16. Ge B, McDermott PF, White DG et al. Role of efflux pumps and topoisomerase mutations in fluoroquinolone resistance in Campylobacter jejuni and Campylobacter coli. Antimicrob Agents Chemother 2005; 49: 3347-54.
17. Zhang Q, Plummer PJ. Mechanisms of antibiotic resistance in Campylobacter. In: Nachamkin I, Szymanski CM, Blaser MJ, eds. Campylobacter. Washington, DC, USA: ASM Press, 2008; 263-76.
18. Neyfakh AA, Borsch CM, Kaatz GW. Fluoroquinolone resistance protein NorA of Staphylococcus aureus is a multidrug efflux transporter. Antimicrob Agents Chemother 1993; 37: 128-9.
19. Ubukata K, Itoh-Yamashita N, Konno M. Cloning and expression of the norA gene for fluoroquinolone resistance in Staphylococcus aureus. Antimicrob Agents Chemother 1989; 33: 1535-9.
20. Kaatz GW, Seo SM, Ruble CA. Efflux-mediated fluoroquinolone resistance in Staphylococcus aureus. Antimicrob Agents Chemother 1993; 37: 1086-94.
21. Neyfakh AA, Bidnenko VE, Chen LB. Efflux-mediated multidrug resistance in Bacillus subtilis: similarities and dissimilarities with the mammalian system. Proc Natl Acad Sci USA 1991; 88: 4781-5.
22. Gill MJ, Brenwald NP, Wise R. Identification of an efflux pump gene, pmrA, associated with fluoroquinolone resistance in Streptococcus pneumoniae. Antimicrob Agents Chemother 1999; 43: 187-9.
23. Jonas BM, Murray BE, Weinstock GM. Characterization of emeA, a NorA homolog and multidrug resistance efflux pump, in Enterococcus faecalis. Antimicrob Agents Chemother 2001; 45: 3574-9.
24. Wösten MM, Boeve M, Koot MG et al. Identification of Campylobacter jejuni promoter sequences. J Bacteriol 1998; 180: 594-9.
25. Lin J, Cagliero C, Guo B et al. Bile salts modulate expression of the CmeABC multidrug efflux pump in Campylobacter jejuni. J Bacteriol 2005; 187: 7417-24.
26. Yao R, Alm RA, Trust TJ et al. Construction of new Campylobacter cloning vectors and a new mutational cat cassette. Gene 1993; 130: 127-30.
27. Miethke M, Klotz O, Linne U et al. Ferri-bacillibactin uptake and hydrolysis in Bacillus subtilis. Mol Microbiol 2006; 61: 1413-27.
28. Zhu M, Valdebenito M, Winkelmann G et al. Functions of the siderophore esterases IroD and IroE in iron-salmochelin utilization. Microbiology 2005; 151: 2363-72.
29. Kaatz GW, Seo SM. Inducible NorA-mediated multidrug resistance in Staphylococcus aureus. Antimicrob Agents Chemother 1995; 39: 2650-5.
30. Yoshida H, Bogaki M, Nakamura S et al. Nucleotide sequence and characterization of the Staphylococcus aureus norA gene, which confers resistance to quinolones. J Bacteriol 1990; 172: 6942-9.
31. Pumbwe L, Piddock LJ. Identification and molecular characterisation of CmeB, a Campylobacter jejuni multidrug efflux pump. FEMS Microbiol Lett 2002; 206: 185-9.
32. Palyada K, Sun YQ, Flint A et al. Characterization of the oxidative stress stimulon and PerR regulon of Campylobacter jejuni. BMC Genomics 2009; 10: 481.
33. Bingham-Ramos LK, Hendrixson DR. Characterization of two putative cytochrome c peroxidases of Campylobacter jejuni involved in promoting commensal colonization of poultry. Infect Immun 2008; 76: 1105-14.
34. Grant KA, Park SF. Molecular characterization of katA from Campylobacter jejuni and generation of a catalase-deficient mutant of Campylobacter coli by interspecific allelic exchange. Microbiology 1995; 141: 1369-76.
35. Wai SN, Nakayama K, Umene K et al. Construction of a ferritindeficient mutant of Campylobacter jejuni: contribution of ferritin to iron storage and protection against oxidative stress. Mol Microbiol 1996; 20: 1127-34.
36. Day WA Jr, Sajecki JL, Pitts TM et al. Role of catalase in Campylobacter jejuni intracellular survival. Infect Immun 2000; 68: 6337-45.
37. Palyada K, Threadgill D, Stintzi A. Iron acquisition and regulation in Campylobacter jejuni. J Bacteriol 2004; 186: 4714-29.