Temporally resolved cAMP monitoring in endothelial cells uncovers a thrombin-induced [cAMP] elevation mediated via the Ca2+-dependent production of prostacyclin

Journal of Physiology

Volumn 589, Issue 1, 2011, Pages 181-193

  Werthmann, R C ^a   Lohse, M J ^a   Bunemann M ^a,b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CALMODULIN; CYCLIC AMP; PHOSPHOLIPASE A2; PROSTACYCLIN; PROSTACYCLIN RECEPTOR; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; RECEPTOR BLOCKING AGENT; THROMBIN;

ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME IMMUNOASSAY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; INCUBATION TIME; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RECEPTOR UPREGULATION; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

BIOSENSING TECHNIQUES; CALCIUM; CAPILLARY PERMEABILITY; CELLS, CULTURED; CYCLIC AMP; ENDOTHELIAL CELLS; EPOPROSTENOL; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; PHOSPHOLIPASES A2; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RECEPTORS, PROSTAGLANDIN; SIGNAL TRANSDUCTION; THROMBIN; TIME FACTORS; UP-REGULATION;

EID: 78650314440     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2010.200121     Document Type: Article

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