Cell infiltration and growth in a low density, uncompressed three-dimensional electrospun nanofibrous scaffold

Biomaterials

Volumn 32, Issue 6, 2011, Pages 1583-1590

  Blakeney, Bryan A ^a   Tambralli, Ajay ^a   Anderson, Joel M ^a   Andukuri, Adinarayana ^a   Lim, Dong Jin ^a   Dean, Derrick R ^b   Jun, Ho Wook ^a  

^a and Radiation Oncology   (United States)

^b University of Alabama at Birmingham   (United States)

Author keywords

Biomimetic material; Extracellular matrix (ECM); Nanofibers; Scaffold; Tissue engineering

Indexed keywords

ASSEMBLY PROCESS; CELL INFILTRATION; COTTON BALLS; DENSE STRUCTURES; ELECTROSPUN NANOFIBERS; ELECTROSPUNS; EXTRACELLULAR MATRICES; FLAT-PLATE COLLECTOR; INTERCONNECTIVITY; LASER CONFOCAL MICROSCOPY; LIMITING FACTORS; LOW DENSITY; MICROFIBERS; NANOFIBROUS SCAFFOLDS; NEEDLE-LIKE PROBE; OPEN POROSITY; POROUS STRUCTURES; QUANTITATIVE ANALYSIS; SHEET-LIKE; THREE-DIMENSIONAL SCAFFOLDS; WATER-SOLUBLE FIBERS;

BIOMIMETICS; CONFOCAL MICROSCOPY; COTTON; NANOFIBERS; SCANNING ELECTRON MICROSCOPY; SEEPAGE; SOIL MECHANICS; SPHERES; THREE DIMENSIONAL; TISSUE ENGINEERING;

SCAFFOLDS;

BIOMIMETIC MATERIAL; NANOFIBER; NANOPARTICLE;

ANIMAL CELL; ARTICLE; BETA SHEET; BIOMIMETICS; CELL DENSITY; CELL GROWTH; CELL INFILTRATION; CELL PROLIFERATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTROSPINNING; EXTRACELLULAR MATRIX; GROWTH RATE; NONHUMAN; POROSITY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCANNING ELECTRON MICROSCOPY; SOLUBILITY; THREE DIMENSIONAL IMAGING; TISSUE ENGINEERING;

ANIMALS; CELL LINE; CELL PROLIFERATION; MICROSCOPY, ELECTRON, SCANNING; NANOFIBERS; RATS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

COTTON; ENGINEERING; SCAFFOLDS; SCANNING ELECTRON MICROSCOPY; SEEPAGE; SPHERES; THREE DIMENSIONAL DESIGN; TISSUE;

GOSSYPIUM HIRSUTUM;

EID: 78650294679     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.10.056     Document Type: Article

References (46)

1. Gupta D., Venugopal J., Mitra S., Dev V.G., Ramakrishna S. Nanostructured biocomposite substrates by electrospinning and electrospraying for the mineralization of osteoblasts. Biomaterials 2009, 30(11):2085-2094.
2. Shin M., Yoshimoto H., Vacanti J. In vivo bone tissue engineering using mesenchymal stem cells on a novel electrospun nanofibrous scaffold. Tissue Eng 2004, 10(1-2):33-41.
3. Zhang Y., Venugopal J., El-Turki A., Tamakrishna S., Su B., Lim C. Electrospun biomimetic nanocomposite nanofibers of hydroxyapatite/chitosan for bone tissue engineering. Biomaterials 2008, 29(32):4314-4322.
4. Tortelli F., Cancedda R. Three-dimensional cultures of osteogenic and chondrogenic cells: a tissue engineering approach to mimic bone and cartilage in vitro. Eur Cells Mater 2009, 17:1-14.
5. Chen J., Xu J., Wang A., Zheng M. Scaffolds for tendon and ligament repair: review of the efficacy of commercial products. Expert Rev Med Devic 2009, 6(1):61-73.
6. Kumbar S., Nukavarapu S., James R., Nair L., Laurencin C. Electrospun poly(lactic acid-co-glycolic acid) scaffolds for skin tissue engineering. Biomaterials 2008, 29(30):4100-4107.
7. Zhu X., Cui W., Li X., Jin Y. Electrospun fibrous mats with high porosity as potential scaffolds for skin tissue engineering. Biomacromolecules 2008, 9(7):1795-1801.
8. Prabhakaran M., Venugopal J., Ramakrishna S. Mesenchymal stem cell differentiation to neuronal cells on electrospun nanofibrous substrates for nerve tissue engineering. Biomaterials 2009, 30(28):4996-5003.
9. Feng Z., Chu X., Huang N., Wang T., Wang Y., Shi X., et al. The effect of nanofibrous galactosylated chitosan scaffolds on the formation of rat primary hepatocyte aggregates and the maintenance of liver function. Biomaterials 2009, 30(14):2753-2763.
10. Venugopal J., Ma L.L., Yong T., Ramakrishna S. In vitro study of smooth muscle cells on polycaprolactone and collagen nanofibrous matrices. Cell Biol Int 2005, 29(10):861-867.
11. Jun I., Jeong S., Shin H. The stimulation of myoblast differentiation by electrically conductive sub-micron fibers. Biomaterials 2009, 30(11):2038-2047.
12. Shin M., Ishii O., Sueda T., Vacanti J.P. Contractile cardiac grafts using a novel nanofibrous mesh. Biomaterials 2004, 25(17):3717-3723.
13. Wray L., Orwin E. Recreating the microenvironment of the native cornea for tissue engineering applications. Tissue Eng Pt A 2009, 15(7):1463-1472.
14. Pham Q.P., Sharma U., Mikos A.G. Electrospinning of polymeric nanofibers for tissue engineering applications: a review. Tissue Eng 2006, 12(5):1197-1211.
15. Li W.J., Jiang Y.J., Tuan R.S. Chondrocyte phenotype in engineered fibrous matrix is regulated by fiber size. Tissue Eng 2006, 12(7):1775-1785.
16. Lowery J., Datta N., Rutledge G. Effect of fiber diameter, pore size and seeding method on growth of human dermal fibroblasts in electrospun poly(epsilon-caprolactone) fibrous mats. Biomaterials 2010, 31(3):491-504.
17. Patlolla A., Collins G., Arinzeh T.L. Solvent-dependent properties of electrospun fibrous composites for bone tissue regeneration. Acta Biomater 2010, 6(1):90-101.
18. Eichhorn S.J., Sampson W.W. Statistical geometry of pores and statistics of porous nanofibrous assemblies. J R Soc Interface 2005, 2(4):309-318.
19. Thorvaldsson A., Stenhamre H., Gatenholm P., Walkenstrom P. Electrospinning of highly porous scaffolds for cartilage regeneration. Biomacromolecules 2008, 9(3):1044-1049.
20. Kim T., Chung H., Park T. Macroporous and nanofibrous hyaluronic acid/collagen hybrid scaffold fabricated by concurrent electrospinning and deposition/leaching of salt particles. Acta Biomaterialia 2008, 4(6):1611-1619.
21. Nam J., Huang Y., Agarwai S., Lannutti J. Improved cellular infiltration in electrospun fiber via engineered porosity. Tissue Eng 2007, 13(9):2249-2257.
22. Wei H.-J., Chen C.-H., Lee W.-Y., Chiu I., Hwang S.-M., Lin W.-W., et al. Bioengineered cardiac patch constructed from multilayered mesenchymal stem cells for myocardial repair. Biomaterials 2008, 29(26):3547-3556.
23. Yang X., Shah J.D., Wang H. Nanofiber enabled layer-by-layer approach toward three-dimensional tissue formation. Tissue Eng Pt A 2009, 15(4):945-956.
24. Baker B.M., Gee A.O., Metter R.B., Nathan A.S., Marklein R.A., Burdick J.A., et al. The potential to improve cell infiltration in composite fiber-aligned electrospun scaffolds by the selective removal of sacrificial fibers. Biomaterials 2008, 29(15):2348-2358.
25. Ekaputra A., Prestwich G., Cool S., Hutmacher D. Combining electrospun scaffolds with electrosprayed hydrogels leads to three-dimensional cellularization of hybrid constructs. Biomacromolecules 2008, 9(8):2097-2103.
26. Baker S.C., Atkin N., Gunning P.A., Granville N., Wilson K., Wilson D., et al. Characterisation of electrospun polystyrene scaffolds for three-dimensional in vitro biological studies. Biomaterials 2006, 27(16):3136-3146.
27. Tambralli A., Blakeney B., Anderson J., Kushwaha M., Andukuri A., Dean D., et al. A hybrid biomimetic scaffold composed of electrospun polycaprolactone nanofibers and self-assembled peptide amphiphile nanofibers. Biofabrication 2009, 1(2):025001.
28. Murugan R., Ramakrishna S. Design strategies of tissue engineering scaffolds with controlled fiber orientation. Tissue Eng 2007, 13(8):1845-1866.
29. Yang S., Leong K.F., Du Z., Chua C.K. The design of scaffolds for use in tissue engineering: I. Traditional factors. Tissue Eng 2001, 7(6):679-689.
30. Choi J.S., Lee S.J., Chris G.J., Atala A., Yoo J.J. The influence of electrospun aligned poly(epsilon-caprolactone)/collagen nanofiber meshes on the formation of self-aligned skeletal muscle myotubes. Biomaterials 2008, 29(19):2899-2906.
31. Li W.J., Danielson K.G., Alexander P.G., Tuan R.S. Biological response of chondrocytes cultured in three-dimensional nanofibrous poly(epsilon-caprolactone) scaffolds. J Biomed Mater Res A 2003, 67(4):1105-1114.
32. Li W.J., Tuli R., Okafor C., Derfoul A., Danielson K.G., Hall D.J., et al. A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells. Biomaterials 2005, 26(6):599-609.
33. Ma Z., He W., Yong T., Ramakrishna S. Grafting of gelatin on electrospun poly(caprolactone) nanofibers to improve endothelial cell spreading and proliferation and to control cell orientation. Tissue Eng 2005, 11(7-8):1149-1158.
34. Yoshimoto H., Shin Y.M., Terai H., Vacanti J.P. A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering. Biomaterials 2003, 24(12):2077-2082.
35. Zhang Y.Z., Venugopal J., Huang Z.M., Lim C.T., Ramakrishna S. Characterization of the surface biocompatibility of the electrospun PCL-collagen nanofibers using fibroblasts. Biomacromolecules 2005, 6(5):2583-2589.
36. Asfari M., Janjic D., Meda P., Li G., Halban P.A., Wollheim C.B. Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology 1992, 130(1):167-178.
37. + channel-dependent and -independent glucose-stimulated insulin secretion. Diabetes 2000, 49(3):424-430.
38. Yang S., Fransson U., Fagerhus L., Holst L.S., Hohmeier H.E., Renstrom R., et al. Enhanced cAMP protein kinase A signaling determines improved insulin secretion in a clonal insulin-producing deta-cell line (INS-1 832/13). Mol Endocrinol 2004, 18(9):2312-2320.
39. Daley W.P., Peters S.B., Larsen M. Extracellular matrix dynamics in development and regenerative medicine. J Cell Sci 2008, 121(Pt 3):255-264.
40. Hubbell J.A. Materials as morphogenetic guides in tissue engineering. Curr Opin Biotechnol 2003, 14(5):551-558.
41. Kleinman H.K., Philip D., Hoffman M.P. Role of the extracellular matrix in morphogenesis. Curr Opin Biotechnol 2003, 14(5):526-532.
42. Streuli C. Extracellular matrix remodeling and cellular differentiation. Curr Opin Cell Biol 1999, 11(5):634-640.
43. Kwon I.K., Kidoaki S., Matsuda T. Electrospun nano- to microfiber fabrics made of biodegradable copolyesters: structural characteristics, mechanical properties and cell adhesion potential. Biomaterials 2005, 26(18):3929-3939.
44. Elsdale T., Bard J. Collagen substrata for studies on cell behavior. J Cell Biol 1972, 54(3):626-637.
45. Karageorgiou V., Kaplan D. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials 2005, 26(27):5474-5491.
46. Telemeco T.A., Ayres C., Bowlin G.L., Wnek G.E., Boland E.D., Cohen N., et al. Regulation of cellular infiltration into tissue engineering scaffolds composed of submicron diameter fibrils produced by electrospinning. Acta Biomater 2005, 1(4):377-385.