Franklinolidesa A - C from an Australian marine sponge complex: Phosphodiesters strongly enhance polyketide cytotoxicity

Angewandte Chemie - International Edition

Volumn 49, Issue 51, 2010, Pages 9904-9906

  Zhang, Hua ^a   Conte, Melissa M ^a   Capon, Robert J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

cytotoxicity; franklinolides; natural products; phosphodiesters; polyketides

Indexed keywords

CYTOTOXIC; FRANKLINOLIDES; IN-VITRO; MARINE SPONGE; NATURAL PRODUCTS; PHOSPHODIESTERS; POLYKETIDES; STRUCTURE ACTIVITY RELATIONSHIPS;

CELL PROLIFERATION; ESTERS;

CYTOTOXICITY;

ALKENE; ANTINEOPLASTIC AGENT; FRANKLINOLIDE A; FRANKLINOLIDE B; FRANKLINOLIDE C; MACROLIDE; ORGANOPHOSPHATE; PYRONE DERIVATIVE;

ANIMAL; ARTICLE; AUSTRALIA; CELL DEATH; DRUG EFFECT; HUMAN; SPONGE (PORIFERA); SYNTHESIS; TUMOR CELL LINE;

ALKENES; ANIMALS; ANTINEOPLASTIC AGENTS; AUSTRALIA; CELL DEATH; CELL LINE, TUMOR; HUMANS; MACROLIDES; PHOSPHORIC ACID ESTERS; PORIFERA; PYRONES;

EID: 78650270803     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201005883     Document Type: Article

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