A case of late epidural hematoma in a patient on clopidogrel therapy postoperatively: When is it safe to resume antiplatelet agents?

Spine Journal

Volumn 11, Issue 1, 2011, Pages e1-

  Carragee, Eugene J ^a   Golish, S Raymond ^a   Scuderi, Gaetano J ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

anticoagulants; clopidogrel; Complications; epidural hematoma; spine surgery

Indexed keywords

CLOPIDOGREL;

ADULT; ARTICLE; CASE REPORT; DRUG WITHDRAWAL; EPIDURAL HEMATOMA; HUMAN; MALE; PATIENT MONITORING; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RADICULOPATHY; SPINAL CORD DECOMPRESSION; SPONDYLOLISTHESIS; STENT; STENT THROMBOSIS; VERTEBRAL CANAL STENOSIS;

EID: 78650265941     PISSN: 15299430     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.spinee.2010.10.013     Document Type: Article

References (27)

1. C.A. Polanczyk, E. Marcantonio, and J. Goldman Impact of age on perioperative complications and length of stay in patients undergoing noncardiac surgery Ann Intern Med 134 2001 637 643 (Pubitemid 32322241)
2. Antithrombotic Trialists' Collaboration Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients BMJ 324 2002 71 86
3. D.E. Spanier, and J.L. Stambough Delayed postoperative epidural hematoma formation after heparinization in lumbar spinal surgery J Spinal Disord 13 2000 46 49
4. A.A. Weber, M. Braun, and T. Hohlfeld Recovery of platelet function after discontinuation of clopidogrel treatment in healthy volunteers Br J Clin Pharmacol 52 2001 333 336 (Pubitemid 33796233)
5. J.Y. Tan, W.H. Shi, and J. He A clinical trial of using antiplatelet therapy to prevent restenosis following peripheral artery angioplasty and stenting Zhonghua Yi Xue Za Zhi 88 2008 812 815 (Pubitemid 351756799)
6. D.W. Park, S.W. Park, and S.W. Lee Frequency of coronary arterial late angiographic stent thrombosis (LAST) in the first six months: outcomes with drug-eluting stents versus bare metal stents Am J Cardiol 99 2007 774 778
7. The CURE Investigators Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation N Engl J Med 345 2001 494 502 (Pubitemid 32758501)
8. J.C. Merritt, and D.L. Bhatt The efficacy and safety of perioperative antiplatelet therapy J Thromb Thrombolysis 13 2002 97 103
9. J. Kou, J. Fischgrund, and A. Biddinger Risk factors for spinal epidural hematoma after spinal surgery Spine 27 2002 1670 1673 (Pubitemid 34839653)
10. I.G. McQuarrie Recovery from paraplegia caused by spontaneous spinal epidural hematoma Neurology 28 1978 224 228 (Pubitemid 8312867)
11. M. Miyazaki, M. Takasita, and H. Matsumoto Spinal epidural hematoma after removal of an epidural catheter. Case report review of the literature J Spinal Disord Tech 18 2005 547 551 (Pubitemid 44384051)
12. N.G. Rainov, V. Heidecke, and W.L. Burkert Spinal epidural hematoma: report of a case and review of the literature Neurosurg Rev 18 1995 53 60
13. S. Mirkovic, and M. Melany A thoracolumbar epidural hematoma simulating a disc syndrome J Spinal Disord 5 1992 112 115
14. J.N. Awad, K.M. Kebaish, and J. Donigan Analysis of the risk factors for the development of post-operative spinal epidural haematoma J Bone Joint Surg Br 87 2005 1248 1252 (Pubitemid 41387566)
15. R.J. Groen, and H. Ponssen The spontaneous spinal epidural hematoma. A study of the etiology J Neurol Sci 98 1990 121 138 (Pubitemid 20288807)
16. J. Uribe, K. Moza, and O. Jimenez Delayed postoperative spinal epidural hematomas Spine J 3 2003 125 129 (Pubitemid 38351762)
17. M.T. Lawton, R.W. Porter, and J.E. Heiserman Surgical management of spinal epidural hematoma: relationship between surgical timing and neurological outcome J Neurosurg 83 1995 1 7
18. R. Gerlach, A. Raabe, and J. Beck Postoperative nadroparin administration for prophylaxis of thromboembolic events is not associated with an increased risk of hemorrhage after spinal surgery Eur Spine J 13 2004 9 13 (Pubitemid 38269943)
19. M.J. Sokolowski, T.A. Garvey, and J. Perl Postoperative lumbar epidural hematoma. Does size really matter? Spine 33 2008 114 119
20. CAPRIE Steering Committee A randomised, blinded trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE) Lancet 348 1996 1329 1339
21. M.P. Glotzbecker, C.M. Bono, and M.B. Harris Surgeon practices regarding postoperative thromboembolic prophylaxis after high-risk spinal surgery Spine 33 2008 2915 2921
22. M.N. Di Minno, D. Prisco, and A.L. Ruocco Perioperative handling of patients on antiplatelet therapy with need for surgery Intern Emerg Med 4 2009 279 288
23. G.L. Kałuza, J. Joseph, and J.R. Lee Catastrophic outcomes of noncardiac surgery soon after coronary stenting J Am Coll Cardiol 35 2000 1288 1294 (Pubitemid 30206904)
24. A.K. Sharma, A.E. Ajani, and S.M. Hamwi Major noncardiac surgery following coronary stenting: when is it safe to operate? Catheter Cardiovasc Interv 63 2004 141 145
25. A. Assali, H. Vaknin-Assa, and E. Lev The risk of cardiac complications following noncardiac surgery in patients with drug eluting stents implanted at least six months before surgery Catheter Cardiovasc Interv 74 2009 837 843
26. K.K. Chia, J.J. Park, and J. Postle Frequency of late drug-eluting stent thrombosis with non-cardiac surgery Am J Cardiol 106 2010 1 3
27. A.T. Fuchs, A. Kuehnl, and J. Pelisek Meta-analysis shows similar risk of thrombosis after drug-eluting stent, bare-metal stent, or angioplasty Endothelium 15 2008 93 100 (Pubitemid 351894983)