Novel staining pattern of p53 in Barrett's dysplasia - the absent pattern

Histopathology

Volumn 57, Issue 6, 2010, Pages 933-935

  Kaye, Philip V ^a   Haider, Syeda A ^a   James, Peter D ^a   Soomro, Irshad ^a   Catton, James ^a   Parsons, Simon L ^a   Ragunath, Krish ^a   Ilyas, Mohammad ^a  

^a NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

BARRETT ESOPHAGUS; DYSPLASIA; ESOPHAGEAL ADENOCARCINOMA; GENE MUTATION; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; LETTER; PRIORITY JOURNAL; STAINING;

BARRETT ESOPHAGUS; DISEASE PROGRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; TUMOR SUPPRESSOR PROTEIN P53;

EID: 78650251752     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/j.1365-2559.2010.03715.x     Document Type: Letter

References (8)

1. Haggitt RC. Barrett's esophagus, dysplasia and adenocarcinoma. Hum. Pathol. 1994; 24; 982-993.
2. Montgomery E, Bronner MP, Goldblum JR et al. Reproducibility of the diagnosis of dysplasia in Barrett esophagus: a reaffirmation. Hum. Pathol. 2001; 32; 368-378.
3. Kaye PV, Haider SA, Ilyas M et al. Barrett's dysplasia and the Vienna classification: reproducibility, prediction of progression and impact of consensus reporting and p53 immunohistochemistry. Histopathology 2009; 54; 699-712.
4. Skacel M, Petras RE, Rybicki LA et al. p53 expression in low grade dysplasia in Barrett's esophagus: correlation with interobserver agreement and disease progression. Am. J. Gastroenterol. 2002; 97; 2508-2513.
5. Murray L, Sedo A, Scott M et al. TP53 and progression from Barrett's metaplasia to oesophageal adenocarcinoma in a UK population cohort. Gut 2006; 55; 1390-1397.
6. Sikkema M, Kerkhof M, Steyerberg EW et al. Aneuploidy and overexpression of Ki67 and p53 as markers for neoplastic progression in Barrett's esophagus: a case-control study. Am. J. Gastroenterol. 2009; 104; 2673-2680.
7. J-F Fle'jou. Barrett's oesophagus: from metaplasia to dysplasia and cancer. Gut 2005; 54(Suppl. I); i6-i12.
8. Wongsurawat VJ, Finley JC, Galipeau PC. Genetic mechanisms of TP53 loss of heterozygosity in Barrett's esophagus: implications for biomarker validation. Cancer Epidemiol. Biomarkers Prev. 2006; 15; 509-516.