Identification and characterization of a phospholipase A2 from the venom of the Saw-scaled viper: Novel bactericidal and membrane damaging activities

Enfermedades Infecciosas y Microbiologia Clinica

Volumn 28, Issue SUPPL. 3, 2010, Pages 1854-1866

  Perumal Samy, Ramar ^a,b   Gopalakrishnakone, P ^a   Bow, Ho ^c   Puspharaj, Peter N ^d   Chow, Vincent T K ^c  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Bactericidal activity; Echis carinatus; Myotoxin; Phospholipase A2; Snake venom

Indexed keywords

AMINO ACID; CEFTAZIDIME; CHLORAMPHENICOL; ECHIS CARINATUS TOXIN 1 PROTEIN; PENICILLIN G; PHOSPHOLIPASE A2; STREPTOMYCIN; UNCLASSIFIED DRUG; VANCOMYCIN; VIPER VENOM; ECTX I ENZYME; SNAKE VENOM;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; BURKHOLDERIA PSEUDOMALLEI; CONTROLLED STUDY; CYTOTOXICITY; DISULFIDE BOND; ECHIS CARINATUS; ENTEROBACTER AEROGENES; ERYTHROCYTE; ESCHERICHIA COLI; HEMOLYSIS; HUMAN; IN VITRO STUDY; LIVER TOXICITY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MEMBRANE DAMAGE; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NEPHROTOXICITY; NEUROTOXICITY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEUS MIRABILIS; PROTEUS VULGARIS; PSEUDOMONAS AERUGINOSA; SKIN TOXICITY; SNAKE; STAPHYLOCOCCUS AUREUS; BACTERIAL CELL; DRUG ACTIVITY; DRUG ANALYSIS; DRUG IDENTIFICATION; DRUG ISOLATION; GEL FILTRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; HUMAN CELL; MALE;

AMINO ACID SEQUENCE; ANIMALS; ANTI-BACTERIAL AGENTS; BRAIN; BURKHOLDERIA PSEUDOMALLEI; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENTEROBACTER AEROGENES; HEMOLYSIS; HUMANS; LIVER; MALE; MICE; MICE, INBRED BALB C; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASES A2; SEQUENCE HOMOLOGY, AMINO ACID; SKIN; VIPER VENOMS; VIPERIDAE;

BURKHOLDERIA PSEUDOMALLEI; ECHIS CARINATUS; ENTEROBACTER AEROGENES; ESCHERICHIA COLI; MUS; NEGIBACTERIA; POSIBACTERIA; PROTEUS MIRABILIS; PROTEUS VULGARIS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

EID: 78650251343     PISSN: 0213005X     EISSN: 15781852     Source Type: Journal    
DOI: 10.1016/j.biochi.2010.07.012     Document Type: Article

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