Obesity-related immunodeficiency in patients with pandemic influenza H1N1

The Lancet Infectious Diseases

Volumn 11, Issue 1, 2011, Pages 14-15

  Nave, Heike ^a   Beutel, Gernot ^a   Kielstein, Jan T ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE;

ADIPOCYTE; DIET; DISEASE ASSOCIATION; HUMAN; IMMUNE DEFICIENCY; INFLUENZA; INFLUENZA VIRUS A H1N1; LETTER; MOLECULAR INTERACTION; NONHUMAN; OBESITY; PANDEMIC; PRIORITY JOURNAL;

ADIPOCYTES; ADIPOKINES; ANIMALS; CRITICAL ILLNESS; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; KILLER CELLS, NATURAL; MACROPHAGES; OBESITY; RATS; SIGNAL TRANSDUCTION;

EID: 78650240393     PISSN: 14733099     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1473-3099(10)70304-2     Document Type: Letter

References (5)

1. Huttunen R, Syrjänen J Obesity and the outcome of infection. Lancet Infect Dis 2010, 10:442-443.
2. Dixit VD Adipose-immune interactions during obesity and caloric restriction: reciprocal mechanisms regulating immunity and health span. J Leukoc Biol 2008, 84:882-892.
3. Falagas ME, Kompoti M Obesity and infection. Lancet Infect Dis 2006, 6:438-446.
4. Nave H, Mueller G, Siegmund B, et al. Resistance of Janus kinase-2 dependent leptin signaling in natural killer (NK) cells: a novel mechanism of NK cell dysfunction in diet-induced obesity. Endocrinology 2008, 149:3370-3378.
5. Smith AG, Sheridan PA, Harp JB, Beck MA Diet-induced obese mice have increased mortality and altered immune responses when infected with influenza virus. J Nutr 2007, 137:1236-1243.