A validated RP-HPLC method for quantitative determination of related impurities of ursodeoxycholic acid (API) by refractive index detection

Journal of Pharmaceutical and Biomedical Analysis

Volumn 54, Issue 4, 2011, Pages 845-849

  Peepliwal, Ashok ^a   Bonde, C G ^a   Bothara, K G ^a  

^a School of Pharmacy and Technology Management   (India)

Author keywords

HPLC; Impurities; Refractive index detector; Ursodeoxycholic acid

Indexed keywords

ACETIC ACID; CHENODEOXYCHOLIC ACID; CHOLIC ACID; DEOXYCHOLIC ACID; LITHOCHOLIC ACID; METHANOL; URSOCHOLIC ACID; URSODEOXYCHOLIC ACID;

ARTICLE; CORRELATION COEFFICIENT; DRUG ABSORPTION; DRUG DETERMINATION; DRUG IMPURITY; FLOW RATE; LINEAR SYSTEM; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REFRACTION INDEX; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY AND SPECIFICITY; TEMPERATURE; VALIDATION STUDY;

CHOLIC ACIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CONTAMINATION; GASTROINTESTINAL AGENTS; LIMIT OF DETECTION; MICROCHEMISTRY; REFRACTOMETRY; REPRODUCIBILITY OF RESULTS; SOLVENTS; TECHNOLOGY, PHARMACEUTICAL; URSODEOXYCHOLIC ACID;

EID: 78650238662     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.10.001     Document Type: Article

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