Impact of hypovitaminosis D and alfacalcidol therapy on survival of hemodialysis patients: Results from the French ARNOS study

Nephron - Clinical Practice

Volumn 118, Issue 2, 2011, Pages

  Jean, G ^a   Lataillade, D ^b   Genet, L ^c   Legrand, E ^d   Kuentz, F ^e   Moreau Gaudry, X ^e   Fouque, D ^c  

^a Centre de Rein Artificiel de Tassin   (France)

^b Centre de Néphrologie du Mont Blanc   (France)

^c UNIVERSITÉ LYON 1   (France)

^d CENTRE HOSPITALIER   (France)

^e AGDUC   (France)

Author keywords

Alfacalcidol; Hemodialysis; Mineral metabolism; Survival rate; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; ALFACALCIDOL; CALCIFEDIOL; CALCIUM; COLECALCIFEROL; PHOSPHORUS;

ADULT; AGED; ARTICLE; CALCIUM BLOOD LEVEL; CARDIOVASCULAR DISEASE; DIABETES MELLITUS; DRUG EFFECT; FEMALE; FRANCE; HAZARD RATIO; HEMODIALYSIS; HEMODIALYSIS PATIENT; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MORTALITY; PHOSPHATE BLOOD LEVEL; PREVALENCE; PRIORITY JOURNAL; SURVIVAL RATE; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; VITAMIN SUPPLEMENTATION;

AGED; AGED, 80 AND OVER; COHORT STUDIES; CROSS-SECTIONAL STUDIES; FEMALE; FRANCE; HUMANS; HYDROXYCHOLECALCIFEROLS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RENAL DIALYSIS; SURVIVAL RATE; VITAMIN D DEFICIENCY;

EID: 78650228639     PISSN: 16602110     EISSN: 16602110     Source Type: Journal    
DOI: 10.1159/000321507     Document Type: Article

References (34)

1. Mehrotra R, Kermah DA, Salusky IB, Wolf MS, Thadhani RI, Chiu Y-W, Martins D, Adler SG, Norris KC: Chronic kidney disease, hypovitaminosis D, and mortality in the United States. Kidney Int 2009; 76: 977-983.
2. Jean G, Charra B, Chazot C: Vitamin D deficiency and associated factors in hemodialysis patients. J Ren Nutr 2008; 18: 395-399.
3. Wolf M, Shah A, Gutierrez O, Ankers E, Monroy M, Tamez H, Steele D, Chang Y, Camargo CA Jr, Tonelli M, Thadhani R: Vitamin D levels and early mortality among incident hemodialysis patients. Kidney Int 2007; 72: 1004-1013. (Pubitemid 47530570)
4. Holick MF: Vitamin D deficiency. N Engl J Med 2007; 357: 266-281.
5. Dawson-Hughes B, Heaney RP, Holick MF, Lips P, Meunier PJ, Vieth R: Estimates of optimal vitamin D status. Osteoporos Int 2005; 16: 713-716. (Pubitemid 40933586)
6. Barreto DV, Barreto FC, Liabeuf S, Temmar M, Boitte F, Choukroun G, Fournier A, Massy ZA: Vitamin D affects survival independently of vascular calcification in chronic kidney disease. Clin J Am Soc Nephrol 2009; 4: 1128-1135.
7. Ravani P, Malberti F, Tripepi G, Pecchini P, Cutrupi S, Pizzini P, Mallamaci F, Zoccali C: Vitamin D levels and patient outcome in chronic kidney disease. Kidney Int 2008; 75: 88-95.
8. Shoji T, Shinohara K, Kimoto E, Emoto M, Tahara H, Koyama H, Inaba M, Fukumoto S, Ishimura E, Miki T, Tabata T, Nishizawa Y: Lower risk for cardiovascular mortality in oral 1alpha-hydroxy vitamin D 3 users in a haemodialysis population. Nephrol Dial Transplant 2004; 19: 179-184. (Pubitemid 38072630)
9. Teng M, Wolf M, Lowrie E, Ofsthun N, Lazarus JM, Thadhani R: Survival of patients undergoing hemodialysis with paricalcitol or calcitriol therapy. N Engl J Med 2003; 349: 446-456. (Pubitemid 36910023)
10. Kalantar-Zadeh K, Kuwae N, Regidor DL, Kovesdy CP, Kilpatrick RD, Shinaberger CS, McAllister CJ, Budoff MJ, Salusky IB, Kopple JD: Survival predictability of time-varying indicators of bone disease in maintenance hemodialysis patients. Kidney Int 2006; 70: 771-780. (Pubitemid 44215354)
11. Gurlek A, Pittelkow MR, Kumar R: Modulation of growth factor/cytokine synthesis and signaling by 1alpha,25-dihydroxyvitamin D 3 : Implications in cell growth and differentiation. Endocr Rev 2002; 23: 763-786. (Pubitemid 35454588)
12. Garland CF, Gorham ED, Mohr SB, Garland FC: Vitamin D for cancer prevention: Global perspective. Ann Epidemiol 2009; 19: 468-483.
13. Scragg R, Sowers M, Bell C: Serum 25-hydroxyvitamin D, diabetes, and ethnicity in the Third National Health and Nutrition Examination Survey. Diabetes Care 2004; 27: 2813-2818. (Pubitemid 39565042)
14. Scragg R, Jackson R, Holdaway IM, Lim T, Beaglehole R: Myocardial infarction is inversely associated with plasma 25-hydroxyvitamin D3 levels: A community-based study. Int J Epidemiol 1990; 19: 559-563. (Pubitemid 20331800)
15. Drinka PJ: The importance of parathyroid hormone and vitamin D status in the treatment of osteoporosis and renal insufficiency. J Am Med Dir Assoc 2006; 7:S5-S9, 4. (Pubitemid 43264466)
16. Bischoff-Ferrari HA, Dietrich T, Orav EJ, Hu FB, Zhang Y, Karlson EW, Dawson-Hughes B: Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged 6 60 years. The Am J Clin Nutr 2004; 80: 752-758. (Pubitemid 41115542)
17. Ruohola P: Association between serum 25(OH)D concentrations and bone stress fractures in Finnish young men. J Bone Miner Res 2006; 21: 1483-1488.
18. Bischoff-Ferrari HA, Giovannucci E, Willett WC, Dietrich T, Dawson-Hughes B: Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. Am J Clin Nutr 2006; 84: 18-28. (Pubitemid 44699167)
19. Eknoyan G, Levin A, Levin NW: Bone metabolism and disease in chronic kidney disease. Am J Kidney Dis 2003; 42: 1-201.
20. KDIGO C-M, Work Group KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease-mineral and bone disorder (CKD-MBD). Kidney Int 2009; 76:S1-S130.
21. Jean G, Terrat J-C, Vanel T, Hurot J-M, Lorriaux C, Mayor B, Chazot C: Daily oral 25-hydroxycholecalciferol supplementation for vitamin D deficiency in haemodialysis patients: Effects on mineral metabolism and bone markers. Nephrol Dial Transplant 2008; 23: 3670-3676.
22. Jean G, Souberbielle JC, Chazot C: Monthly cholecalciferol administration in haemodialysis patients: A simple and efficient strategy for vitamin D supplementation. Nephrol Dial Transplant 2009; 24: 3799-3805.
23. Jacob AI, Sallman A, Santiz Z, Hollis BW: Defective photoproduction of cholecalciferol in normal and uremic humans. J Nutr 1984; 114: 1313-1319.
24. Melamed ML, Michos ED, Post W, Astor B: 25-hydroxyvitamin D levels and the risk of mortality in the general population. Arch Intern Med 2008; 168: 1629-1637.
25. Ravani P, Malberti F, Tripepi G, Pecchini P, Cutrupi S, Pizzini P, Mallamaci F, Zoccali C: Vitamin D levels and patient outcome in chronic kidney disease. Kidney Int 2008; 75: 88-95.
26. Tentori F, Hunt WC, Stidley CA, Rohrscheib MR, Bedrick EJ, Meyer KB, Johnson HK, Zager PG: Mortality risk among hemodialysis patients receiving different vitamin D analogs. Kidney Int 2006; 70: 1858-1865. (Pubitemid 44684819)
27. Kovesdy CP, Ahmadzadeh S, Anderson JE, Kalantar-Zadeh K: Association of activated vitamin D treatment and mortality in chronic kidney disease. Arch Int Med 2008; 168: 397-403. (Pubitemid 351350586)
28. Kovesdy CP, Kalantar-Zadeh K: Vitamin D receptor activation and survival in chronic kidney disease. Kidney Int 2008; 73: 1355-1363. (Pubitemid 351770491)
29. Nordal KP, Dahl E, Halse J, Attramadal A, Flatmark A: Long-term low-dose calcitriol treatment in predialysis chronic renal failure: Can it prevent hyperparathyroid bone disease? Nephrol Dial Transplant 1995; 10: 203-206.
30. Sprague SM, Lerma E, McCormmick D, Abraham M, Batlle D: Suppression of parathyroid hormone secretion in hemodialysis patients: Comparison of paricalcitol with calcitriol. Am J Kidney Dis 2001; 38:S51-S56. (Pubitemid 33022206)
31. Gupta A, Kallenbach LR, Zasuwa G, Divine GW: Race is a major determinant of secondary hyperparathyroidism in uremic patients. J Am Soc Nephrol 2000; 11: 330-334. (Pubitemid 30064856)
32. Tentori F, Albert JM, Young EW, Blayney MJ, Robinson BM, Pisoni RL, Akiba T, Greenwood RN, Kimata N, Levin NW, Piera LM, Saran R, Wolfe RA, Port FK: The survival advantage for haemodialysis patients taking vitamin D is questioned: Findings from the dialysis outcomes and practice patterns study. Nephrol Dial Transplant 2009; 24: 963-972.
33. Naves-Diaz M, Alvarez-Hernandez D, Passlick- Deetjen J, Guinsburg A, Marelli C, Rodriguez- Puyol D, Cannata-Andia JB: Oral active vitamin D is associated with improved survival in hemodialysis patients. Kidney Int 2008: 1070-1078.
34. Shroff R, Egerton M, Bridel M, Shah V, Donald AE, Cole TJ, Hiorns MP, Deanfield JE, Rees L: A bimodal association of vitamin D levels and vascular disease in children on dialysis. J Am Soc Nephrol 2008; 19: 1239-1246.