Microfluidic direct injection method for analysis of urinary 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) using molecularly imprinted polymers coupled on-line with LC-MS/MS

Journal of Pharmaceutical and Biomedical Analysis

Volumn 54, Issue 2, 2011, Pages 368-378

  Shah, Kumar A ^a   Peoples, Michael C ^b   Halquist, Matthew S ^a   Rutan, Sarah C ^a   Karnes, Thomas H ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b Pfizer Consumer Healthcare   (United States)

Author keywords

LC MS MS; Molecularly imprinted polymer; NNAL; On line microfluidic solid phase extraction; Tobacco specific nitrosamine

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANOL; POLYMER;

ACCURACY; ADULT; ARTICLE; CLINICAL ARTICLE; DRUG STRUCTURE; DRUG URINE LEVEL; ETHNICITY; EXTRACTION; FEMALE; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INJECTION; LIQUID CHROMATOGRAPHY; MALE; MICROFLUIDIC ANALYSIS; MOLECULAR IMPRINTING; PH; PRIORITY JOURNAL; QUALITY CONTROL; SMOKING; TANDEM MASS SPECTROMETRY; URINALYSIS; VALIDATION PROCESS;

ADULT; BUTANOLS; CALIBRATION; CHROMATOGRAPHY, LIQUID; FEMALE; GLUCURONATES; HUMANS; MALE; MICROFLUIDICS; MIDDLE AGED; MOLECULAR IMPRINTING; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; NITROSAMINES; ONLINE SYSTEMS; POLYMERS; PYRIDINES; QUALITY CONTROL; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY; TIME FACTORS;

EID: 78650223051     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.09.001     Document Type: Article

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