The arcuate nucleus as a circumventricular organ in the mouse

Neuroscience Letters

Volumn 487, Issue 2, 2011, Pages 187-190

  Ciofi, Philippe ^a,b  

^a INSTITUT FRANÇOIS MAGENDIE   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

Arcuate nucleus; Blood brain barrier; Hormonal feedback; Hypothalamus; Median eminence; Permeability; Tanycytes

Indexed keywords

ANTIGEN MECA32; CELL ANTIGEN; IMMUNOGLOBULIN; MONOCLONAL ANTIBODY; PROTEIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARCUATE NUCLEUS; ARTICLE; BLOOD BRAIN BARRIER; BRAIN PERFUSION; BRAIN VENTRICLE; CELL MEMBRANE PERMEABILITY; CIRCUMVENTRICULAR ORGAN; CONTROLLED STUDY; DIAPHRAGM; ENDOTHELIUM CELL; MALE; MEDIAN EMINENCE; MICROVASCULATURE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; THALAMUS VENTRAL NUCLEUS; TISSUE FIXATION;

EID: 78650199265     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.10.019     Document Type: Article

References (20)

1. Ambach G., Palkovits M., Szentagothai J. Blood supply of the rat hypothalamus. IV. Retrochiasmatic area, median eminence, arcuate nucleus. Acta Morphol. Acad. Sci. Hung. 1976, 24:93-119.
2. Bearer E.L., Orci L. Endothelial fenestral diaphragms: a quick-freeze, deep-etch study. J. Cell Biol. 1985, 100:418-428.
3. Broadwell R.D., Balin B.J., Salcman M., Kaplan R.S. Brain-blood barrier? Yes and no. Proc. Natl. Acad. Sci. U.S.A. 1983, 80:7352-7356.
4. Broadwell R.D., Sofroniew M.V. Serum proteins bypass the blood-brain fluid barriers for extracellular entry to the central nervous system. Exp. Neurol. 1993, 120:245-263.
5. Ciofi P., Garret M., Lapirot O., Lafon P., Loyens A., Prévot V., Levine J.E. Brain-endocrine interactions: a microvascular route in the mediobasal hypothalamus. Endocrinology 2009, 150:5509-5519.
6. Ciofi P., Leroy D., Tramu G. Sexual dimorphism in the organization of the rat hypothalamic infundibular area. Neuroscience 2006, 141:1731-1745.
7. Duvernoy H.M., Risold P.Y. The circumventricular organs: an atlas of comparative anatomy and vascularization. Brain Res. Rev. 2007, 56:119-147.
8. Gross P.M. Circumventricular organ capillaries. Prog. Brain Res. 1992, 91:219-233.
9. Hallmann R., Mayer D.N., Berg E.L., Broermann R., Butcher E.C. Novel mouse endothelial cell surface marker is suppressed during differentiation of the blood brain barrier. Dev. Dyn. 1995, 202:325-332.
10. Kalimo H. The role of the blood-brain-barrier in perfusion fixation of the brain for electron microscopy. Histochem. J. 1976, 8:1-12.
11. Martinez J.L., Koda L. Penetration of fluorescein into the brain: a sex difference. Brain Res. 1988, 450:81-85.
12. Mullier A., Bouret S.G., Prévot V., Dehouck B. Differential distribution of tight junction proteins suggests a role for tanycytes in blood-hypothalamus barrier regulation in the adult mouse brain. J. Comp. Neurol. 2010, 518:943-962.
13. Page R.B. The anatomy of the hypothalamo-hypophyseal complex. The Physiology of Reproduction 1988, 1161-1233. Raven Press, New York. 1st ed. E. Knobil, J. Neill, L.L. Ewing, G.S. Greenwald, C.L. Markert, D.W. Pfaff (Eds.).
14. Palkovits M. Stress-induced activation of neurons in the ventromedial arcuate nucleus: a blood-brain-CSF interface of the hypothalamus. Ann. N.Y. Acad. Sci. 2008, 1148:57-63.
15. Rodríguez E.M., Blázquez J.L., Guerra M. The design of barriers in the hypothalamus allows the median eminence and the arcuate nucleus to enjoy private milieus: the former opens to the portal blood and the latter to the cerebrospinal fluid. Peptides 2010, 31:757-776.
16. Schulz M., Engelhardt B. The circumventricular organs participate in the immunopathogenesis of experimental autoimmune encephalomyelitis. Cerebrospinal Fluid Res. 2005, 2:8.
17. Shaver S.W., Pang J.J., Wainman D.S., Wall K.M., Gross P.M. Morphology and function of capillary networks in subregions of the rat tuber cinereum. Cell Tissue Res. 1992, 267:437-448.
18. Stan R.V., Kubitza M., Palade G.E. PV-1 is a component of the fenestral and stomatal diaphragms in fenestrated endothelia. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:13203-13207.
19. Tse D., Stan R.V. Morphological heterogeneity of endothelium. Semin. Thromb. Hemost. 2010, 36:236-245.
20. Wsniewski H., Olszewski J. Vascular permeability in the area postrema and the hypothalamus. A study using iodinated radioactive albumin. Neurology 1963, 13:885-894.