RASSF1A polymorphism in familial breast cancer

Familial Cancer

Volumn 9, Issue 3, 2010, Pages 263-265

  Bergqvist, J ^a   Latif, A ^a   Roberts, S A ^a   Hadfield, K D ^a   Lalloo, F ^a   Howell, A ^a,b   Evans, D G ^a,b   Newman, W G ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b WYTHENSHAWE HOSPITAL   (United Kingdom)

Author keywords

BRCA1; BRCA2; Breast cancer; Familial; RASSF1A

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; PROTEIN BRCA; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BREAST CANCER; CANCER PATIENT; CANCER RISK; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; FAMILIAL CANCER; FEMALE; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GERM LINE; HISTOPATHOLOGY; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

BREAST NEOPLASMS; FEMALE; GENES, BRCA1; GENES, BRCA2; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HISTORY, 16TH CENTURY; HUMANS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; TUMOR SUPPRESSOR PROTEINS;

EID: 78650198947     PISSN: 13899600     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10689-010-9335-8     Document Type: Article

References (13)

1. Schagdarsurengin U, Seidel C, Ulbrich EJ et al (2005) A polymorphism at codon 133 of the tumor suppressor RASSF1A is associated with tumorous alteration of the breast. Int J Oncol 27:185-191
2. Gao B, Xie XJ, Huang C et al (2008) RASSF1A polymorphism A133S is associated with early onset breast cancer in BRCA1/2 mutation carriers. Cancer Res 68:22-25
3. Dammann R, Schagdarsurengin U, Seidel C et al (2005) The tumor suppressor RASSF1A in human carcinogenesis: an update. Histol Histopathol 20:645-663 (Pubitemid 40468282)
4. Fackler MJ, McVeigh M, Evron E et al (2003) DNA methylation of RASSF1A, HIN-1, RAR-beta, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma. Int J Cancer 107:970-975
5. Donninger H, Vos MD, Clark GJ (2007) The RASSF1A tumor suppressor. J Cell Sci 120:3163-3172
6. Latif A, Hadfield KD, Roberts SA et al. (2009) Breast cancer susceptibility variants alter risks in familial disease. J Med Genet 47:126-131
7. NICE clinical guideline 41(2006) Familial breast cancer. The classification and care of women at risk of familial breast cancer in primary, secondary and tertiary care
8. R Development Core Team (2007) R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0 URL http://www.R-project.org
9. Evans DG, Eccles DM, Rahman N et al (2004) A new scoring system for the chances of identifying a BRCA1/2 mutation outperforms existing models including BRCAPRO. J Med Genet 41:474-480
10. Antoniou AC, Hardy R, Walker L et al (2008) Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation: validation of BOADICEA, BRCAPRO, IBIS, Myriad and the Manchester scoring system using data from UK genetics clinics. J Med Genet 45:425-431
11. Ioannidis JP (2008) Why most discovered true associations are inflated. Epidemiology 19:640-648
12. Easton DF, Pooley KA, Dunning AM et al (2007) Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 447:1087-1095
13. Hunter DJ, Kraft P, Jacobs KB et al (2007) A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet 39:870-874