Dissolving oral clonazepam wafers in the acute treatment of prolonged seizures

Journal of Child Neurology

Volumn 25, Issue 12, 2010, Pages 1468-1472

  Troester, Matthew M ^a   Hastriter, Eric V ^a   Ng, Yu Tze ^a  

^a BARROW NEUROLOGICAL INSTITUTE   (United States)

Author keywords

clonazepam wafers; epilepsy; Klonopin; seizures

Indexed keywords

CLONAZEPAM; DIAZEPAM;

ADOLESCENT; ADULT; ARTICLE; ATONIC SEIZURE; CHILD; DRUG EFFICACY; FEMALE; FOCAL EPILEPSY; GRAND MAL SEIZURE; HUMAN; MAJOR CLINICAL STUDY; MALE; MYOCLONUS SEIZURE; PRESCHOOL CHILD; PRIORITY JOURNAL; QUESTIONNAIRE; SCHOOL CHILD; SEIZURE;

ACUTE DISEASE; ADMINISTRATION, ORAL; ADOLESCENT; ADULT; AGE FACTORS; ANTICONVULSANTS; CHILD; CHILD, PRESCHOOL; CLONAZEPAM; EPILEPSY; FEMALE; HUMANS; MALE; OUTCOME ASSESSMENT (HEALTH CARE); QUESTIONNAIRES; RETROSPECTIVE STUDIES; STATUS EPILEPTICUS; TIME FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 78650196794     PISSN: 08830738     EISSN: 17088283     Source Type: Journal    
DOI: 10.1177/0883073810368312     Document Type: Article

References (13)

1. Morgan HB, Miller GS Home management of breakthrough seizures. In: Maria BL, ed. Current Management in Child Neurology. 4th ed. Shelton, Connecticut: People's Medical Publishing House ; 2009: 148-152.
2. Shinnar S., Berg AT, Moshe SL How long do new-onset seizures in children last ? Ann Neurol. 2001 ; 49: 659-664.
3. PDR Network. Klonopin wafers. In: Physicians' Desk Reference. 64th ed. Montvale, New Jersey: PDR Network ; 2010: 2855-2856.
4. Lahat E., Goldman M., Barr J., et al. Intranasal midazolam for childhood seizures. Lancet. 1998 ; 352 (9128). 620.
5. Moolenaar F., Baker S., Visser J., et al. Comparative biopharmaceutics of diazepam after single rectal, oral, intramuscular and intravenous administration in man. Int J Pharm. 1980 ; 5: 127-137.
6. Kriel RL, Cloyd JC, Pellock JM, et al. Rectal diazepam gel for treatment of acute repetitive seizures. Pediatr Neurol. 1999 ; 20: 282-288.
7. Driefuss FE, Rosman NP, Cloyd JC, et al. A comparison of rectal diazepam gel and placebo for acute repetitive seizures. N Engl J Med. 1998 ; 338: 1869-1875.
8. Cereghino JJ, Cloyd JC, Kuzniecky RL, et al. Rectal diazepam gel for treatment of acute repetitive seizures in adults. Arch Neurol. 2002 ; 59: 1915-1920.
9. Diastat AcuDial™ package insert. Costa Mesa, California: Valeant Pharmaceuticals ; 2005.
10. VanLandingham KE Analysis of spontaneously reported adverse events with diazepam rectal gel. Epilepsia. 2003 ; 44 (Suppl 9): 280.
11. Holmes GL Partial complex seizures in children: an analysis of 69 seizures in 24 patients using EEG FM radiotelemetry and videotape recording. Electroencephalogr Clin Neurophysiol. 1984 ; 57 (1). 13-20.
12. Drugstore.com Inc. Home page. Available at: www.drugstore.com. Accessed January 1, 2010.
13. Ritter FJ, Frost MD, Karney VL, et al. Cost savings and effectiveness of rectal diazepam for treatment of prolonged or acute repetitive seizures in children 5 years and younger. Neurology. 2000 ; 54 (Suppl 3): A295.